Dr Chloe Thomas PhD

Dr Chloe Thomas

School of Biomedical Sciences
Post Doctoral Fellow

Contact details

Address
Institute of Clinical Sciences
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Chloe Thomas is a Post-Doctoral Researcher within the School of Biomedical Science, Institute of Clinical Sciences and her research interests are in ocular injury and disease and the development of novel therapeutics. She completed her PhD research on cell death mechanisms in the retina and optic nerve after blunt impact and explosive blast ocular trauma. She is currently researching topical therapies for the treatment of age-related macular degeneration.

Qualifications

  • PhD in Inflammation and Ageing, 2019
  • BMedSc, 2015

Biography

Chloe obtained her PhD at the University of Birmingham in 2019 and was supervised by Dr Zubair Ahmed and Lt Col Richard Blanch. Chloe’s PhD research investigated apoptotic and necroptotic cell death pathways in the retina and optic nerve after explosive blast ocular injuries and tested therapeutic agents. She is now a post-doctoral fellow with Dr Lisa Hill and Professor Alastair Denniston and is researching into topical therapies for Age-related Macular Degeneration.

Chloe is also a registered Science, Technology, Engineering and Mathematics (STEM) ambassador and is interested in public engagement and science communication.

Teaching

Research

Research interests

  • Traumatic ocular injury, particular from blast injury.
  • Delivery of therapeutics for ocular disease, including age-related macular degeneration.
  • Cell death pathways.

Other activities

  • Chloe is actively involved in public and patient events such as Brain Awareness Week and Macular Society patient groups and is a Science, Technology, Engineering and Maths ambassador. She was a mentee on ARVO Global Mentorship Programme (2018) and is currently an ARVO Science Communication training fellow (2018-2019) and partakes in the Letters to a Pre-Scientist initiative.
  • Chloe currently holds memberships for The Association of Research in Vision and Ophthalmology (ARVO) (2015-present) and Women in Vision UK (2018-present).
  • Chloe is the Institute of Clinical Sciences representative for Postdoctoral / Early Researcher Career Development and Training (PERCAT) committee at College of Medical and Dental Sciences, University of Birmingham.

Publications

  • Thomas CN, Thompson A, McCance E, Berry M, Logan A, Blanch RJ, Ahmed Z (2018). Caspase-2 mediates site-specific retinal ganglion cell death after blunt ocular injury. Investigative Ophthalmology and Visual Sciences, 59 (11): 4453 DOI: 10.1167/iovs.18-24045
  • Hill LJ, Mead B, Thomas CN, Foale S, Feinstein E, Berry M, Blanch RJ, Ahmed Z and Logan, (2018), TGF-β-induced IOP elevations are mediated by RhoA in the early but not the late fibrotic phase of open angle glaucoma. Molecular Vision, vol. 24, pp. 712-726.
  • Thomas CN, Berry M, Logan A, Blanch RJ, Ahmed Z, (2017). Caspases in retinal ganglion cell death and axon regeneration. Cell Death Discovery 3, 17032. doi:10.1038/cddiscovery.2017.32

View all publications in research portal