Dr Chloe Thomas PhD

Dr Chloe Thomas

School of Biomedical Sciences
Post Doctoral Fellow

Contact details

Telephone
+44 (0)121 414 8859
Email
c.thomas.4@bham.ac.uk
Twitter
@ChloeThomas_Dr
View my research portal
Address
Institute of Clinical Sciences
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Chloe Thomas is a Post-Doctoral Researcher within the School of Biomedical Science, Institute of Clinical Sciences and her research interests are in ocular injury and disease and the development of novel therapeutics. She completed her PhD research on cell death mechanisms in the retina and optic nerve after blunt impact and explosive blast ocular trauma. She is currently researching topical therapies for the treatment of age-related macular degeneration.

Qualifications

  • PhD in Inflammation and Ageing, 2019
  • BMedSc, 2015

Teaching

Other activities

  • Chloe is actively involved in public and patient events such as Brain Awareness Week and Macular Society patient groups and is a Science, Technology, Engineering and Maths ambassador. She was a mentee on ARVO Global Mentorship Programme (2018) and is currently an ARVO Science Communication training fellow (2018-2019) and partakes in the Letters to a Pre-Scientist initiative.
  • Chloe currently holds memberships for The Association of Research in Vision and Ophthalmology (ARVO) (2015-present) and Women in Vision UK (2018-present).
  • Chloe is the Institute of Clinical Sciences representative for Postdoctoral / Early Researcher Career Development and Training (PERCAT) committee at College of Medical and Dental Sciences, University of Birmingham.

Publications

Recent publications

Article

Thomas, C, Alfahad, N, Capewell, N, Cowley, J, Hickman, E, Fernandez, A, Harrison, N, Qureshi, O, Bennett, N, Barnes, N, Dick, A, Chu, C, Liu, X, Denniston, A, Vendrell, M & Hill, LJ 2022, 'Triazole-derivatized near-infrared cyanine dyes enable local functional fluorescent imaging of ocular inflammation', Biosensors and Bioelectronics , vol. 216, 114623. https://doi.org/10.1016/j.bios.2022.114623

Thomas, C, Bernardo-Colón, A, Courtie, E, Essex, G, Rex, TS, Blanch, R & Ahmed, Z 2021, 'Effects of intravitreal injection of siRNA against caspase‑2 on retinal and optic nerve degeneration in air blast induced ocular trauma', Scientific Reports, vol. 11, no. 1, 16839. https://doi.org/10.1038/s41598-021-96107-y

Thomas, CN, Courtie, E, Bernardo-Colón, A, Essex, G, Rex, TS, Ahmed, Z & Blanch, RJ 2020, 'Assessment of necroptosis in the retina in a repeated primary ocular blast injury mouse model', Experimental Eye Research, vol. 197, 108102. https://doi.org/10.1016/j.exer.2020.108102

Thomas, CN, Thompson, AM, Ahmed, Z & Blanch, RJ 2019, 'Retinal Ganglion Cells Die by Necroptotic Mechanisms in a Site-Specific Manner in a Rat Blunt Ocular Injury Model', Cells, vol. 8, no. 12, 1517. https://doi.org/10.3390/cells8121517

Thomas, C, Thompson, A, McCance, E, Berry, M, Logan, A, Blanch, R & Ahmed, Z 2018, 'Caspase-2 mediates site-specific retinal ganglion cell death after blunt ocular injury', Investigative Ophthalmology & Visual Science (IOVS), vol. 59, no. 11, pp. 4453-4462. https://doi.org/10.1167/iovs.18-24045

Hill, LJ, Mead, B, Thomas, CN, Foale, S, Feinstein, E, Berry, M, Blanch, RJ, Ahmed, Z & Logan, A 2018, 'TGF-β-induced IOP elevations are mediated by RhoA in the early but not the late fibrotic phase of open angle glaucoma', Molecular Vision, vol. 24, pp. 712-726. <http://www.molvis.org/molvis/v24/712/>

Review article

Thomas, CN, Sim, DA, Lee, WH, Alfahad, N, Dick, AD, Denniston, A & Hill, LJ 2022, 'Emerging therapies and their delivery for treating age-related macular degeneration', British Journal of Pharmacology, vol. 179, no. 9, pp. 1908-1937. https://doi.org/10.1111/bph.15459

Thomas, C, Berry, M, Logan, A, Blanch, R & Ahmed, Z 2017, 'Caspases in retinal ganglion cell death and axon regeneration', Cell Death Discovery, vol. 3, 17032. https://doi.org/10.1038/cddiscovery.2017.32

View all publications in research portal