Dr Majid Malboubi BSc, MSc, PhD, FHEA

Dr Majid Malboubi

Dubai Campus
Head of Quality Assurance
Assistant Professor of Mechanical Engineering

Contact details

Email
m.malboubi@bham.ac.uk
View my research portal
Address
University of Birmingham Dubai
Dubai International Academic City
PO Box 341799
Dubai, UAE

Dr Majid Malboubi is an assistant professor in Mechanical Engineering.

Inspired by the workings of nature, Dr Malboubi applies the principles of mechanics and design micro-tools to unravel the physics underlying cellular processes and to understand how cells interact with their surroundings. Dr Malboubi completed his PhD at the University of Birmingham and worked on the interaction of biological membranes with solid substrates, and published several articles on this subject, as well as a book (Gigaseal formation in patch clamping, Springer, 2014).

Upon moving to the London Centre of Nanotechnology at UCL, Dr Malboubi worked on the poroelasticity and pressure propagation in cells to explain cells’ ability to sustain transient and prolonged pressure gradients across their cytoplasm in response to extrinsic and intrinsic mechanical stresses. Dr Malboubi also developed several microfluidic devices for cancer metastasis and drug screening. Subsequently, Dr Malboubi moved to the University of Oxford to investigate the effects of mechanical loadings, such as compression or stretch on neural electrophysiological responses and the ability of neurons to fire action potentials after trauma.

Qualifications

  • 2019 – 2021 - Postgraduate Certificate in Higher Education, University of Birmingham
  • 2020 - Fellow of the Higher Education Academy (FHEA)
  • 2007 – 2011 - PhD in Mechanical Engineering, University of Birmingham

Biography

  • 02/2020 – Present          Head of Quality Assurance, University of Birmingham Dubai
  • 06/2018 – Present          Assistant Professor, Department of Mechanical Engineering, University of Birmingham
  • 05/2016 – 05/2018         Researcher Co-Investigator, Department of Engineering Science, University of Oxford
  • 07/2014 – 05/2016         Postdoctoral Researcher, Institute of Biomedical Engineering, University of Oxford
  • 10/2011 – 07/2014         Postdoctoral Researcher,London Centre for Nanotechnology, University College London

Teaching

  • Mechanics
  • Fluid Mechanics
  • Energy Transfer and Thermodynamics
  • Mechanical Design
  • Manufacturing
  • Mechanics Laboratory
  • Fluid Mechanics Laboratory

Research

  • Gigaseal formation
  • Microfluidics
  • Cell and tissue mechanics
  • Substrate-Membrane interactions
  • 3D Printing

Funding

EPSRC Healthcare Technologies Challenge Awards. Electrophysiological-mechanical coupled pulses in neural membranes: a new paradigm for clinical therapy of SCI and TBI (NeuroPulse), £991,283, [EP/N020987/1], Co-Investigator.

Other activities

Memberships

  • Member of Advance HE
  • Member of Biophysical Society
  • Member of International Association of Engineers
  • Member of The Marine Biological Association (2016 – 2018)
  • Member of The Royal Microscopical Society (2010 – 2016)

Reviewer

  • Member of Topical Advisory Panel of Micromachines journal

Publications

Recent publications

Book

Malboubi, M & Jiang, K 2014, Gigaseal formation in patch clamping with applications of nanotechnology. Springer.

Article

Malboubi, M, Jerusalem , A & Bianchi, F 2019, '3D finite element formulation for mechanical–electrophysiological coupling in axonopathy', Computer Methods in Applied Mechanics and Engineering.

Malboubi, M, Jerusalem , A & Contera, S 2019, 'Electrophysiological-mechanical coupling in the neuronal membrane and its role in ultrasound neuromodulation and general anaesthesia', Acta Biomaterialia.

Malboubi, M, Jerusalem, A & Bianchi, F 2019, 'Engineering a uniaxial substrate-stretching device for simultaneous electrophysiological measurements and imaging of strained peripheral neurons', Medical Engineering & Physics.

Malboubi, M, Bianchi, F & Jerusalem, A 2019, 'Ion current and action potential alterations in peripheral neurons subject to uniaxial strain', Journal of Neuroscience Research.

Malboubi, M 2018, 'Fascin regulates nuclear movement and plasticity in migrating cells', Developmental Cell.

Malboubi, M 2018, 'Rapid and efficient differentiation of functional motor neurons from human iPSC for neural injury modelling', Stem Cell Research.

Malboubi, M, Gu, Y & Jiang, K 2011, 'Characterization of surface properties of glass micropipettes using SEM stereoscopic technique', Microelectronic Engineering, vol. 88, no. 8, pp. 2666-2670. https://doi.org/10.1016/j.mee.2011.02.029

Mohammadkhani, A, Malboubi, M, Anthony, C & Jiang, K 2011, 'Characterization of surface properties of ordered nanostructures using SEM stereoscopic technique', Microelectronic Engineering, vol. 88, no. 8, pp. 2687-2690. https://doi.org/10.1016/j.mee.2010.12.039

Chapter

Saadat, M, Hughes, A, Jungclaussen, A, Hajiyavand, A, Poologasundarampillai, G, Moetazedian, A & Malboubi, M 2024, Performance and Optimisation of Microfluidic Channels with Acute Angles and Serpentine Curvatures. in M-R Alam & M Fathi (eds), Integrated Systems: Data Driven Engineering. 1 edn, Springer, pp. 83-100. https://doi.org/10.1007/978-3-031-53652-6_5

Malboubi, M, Charras, G, Parsons, M & Jayo, A 2018, Microfluidic devices for examining the physical limits of migration in confined environments. in Cell Migration . Springer.

Malboubi, M & Jiang, K 2014, Development of patch clamping. in SpringerBriefs in Applied Sciences and Technology. 9783642391279 edn, SpringerBriefs in Applied Sciences and Technology, no. 9783642391279, Springer Verlag, pp. 3-16. https://doi.org/10.1007/978-3-642-39128-6_2

Malboubi, M & Jiang, K 2014, Effect of roughness on gigaseal formation. in SpringerBriefs in Applied Sciences and Technology. 9783642391279 edn, SpringerBriefs in Applied Sciences and Technology, no. 9783642391279, Springer Verlag, pp. 29-47. https://doi.org/10.1007/978-3-642-39128-6_4

Malboubi, M & Jiang, K 2014, Study of glass micropipettes from tip formation to characterization. in SpringerBriefs in Applied Sciences and Technology. 9783642391279 edn, SpringerBriefs in Applied Sciences and Technology, no. 9783642391279, Springer Verlag, pp. 75-94. https://doi.org/10.1007/978-3-642-39128-6_7

Special issue

Malboubi, M, Jayo, A, Parsons, M & Charras, G 2015, 'An open access microfluidic device for the study of the physical limits of cancer cell deformation during migration in confined environments', Microelectronic Engineering, vol. 144, pp. 42-45. https://doi.org/10.1016/j.mee.2015.02.022

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