Recent publications
Article
Richardson, N, Ng, S & Wraith, D 2020, 'Antigen-specific immunotherapy for treatment of autoimmune liver diseases', Frontiers in immunology, vol. 11, 1586. https://doi.org/10.3389/fimmu.2020.01586
Jennings, E, Elliot, T, Thawait, N, Kanabar, S, Yam-Puc, JC, Ono, M, Toellner, K-M, Wraith, DC, Anderson, G & Bending, D 2020, 'Nr4a1 and Nr4a3 reporter mice are differentially sensitive to T cell receptor signal strength and duration', Cell Reports, vol. 33, no. 5, 108328. https://doi.org/10.1016/j.celrep.2020.108328, https://doi.org/10.1016/j.celrep.2020.108328
Shields, A, Faustini, SE, Perez-Toledo, M, Jossi, S, Aldera, E, Allen, JD, Al-Taei, S, Backhouse, C, Bosworth, A, Dunbar, LA, Ebanks, D, Emmanuel, B, Garvey, M, Gray, J, Kidd, IM, McGinnell, G, McLoughlin, DE, Morley, G, O'Neill, J, Papakonstantinou, D, Pickles, O, Poxon, C, Richter, M, Walker, EM, Wanigasooriya, K, Watanabe, Y, Whalley, C, Zielinska, AE, Crispin, M, Wraith, DC, Beggs, AD, Cunningham, AF, Drayson, MT & Richter, AG 2020, 'SARS-CoV-2 seroprevalence and asymptomatic viral carriage in healthcare workers: a cross-sectional study', Thorax, vol. 75, no. 12, pp. 1089-1094. https://doi.org/10.1136/thoraxjnl-2020-215414
Chataway, J, Martin, K, Barrell, K, Sharrack, B, Stolt, P, Wraith, D & ATX-MS1467 Study Group 2018, 'Effects of ATX-MS-1467 immunotherapy over 16 weeks in relapsing multiple sclerosis', Neurology, vol. 90, no. 11, pp. e955-e962. https://doi.org/10.1212/WNL.0000000000005118
Jansson, L, Vrolix, K, Jahraus, A, Martin, KF, Wraith, DC & Wraith, D 2018, 'Immunotherapy with apitopes blocks the immune response to TSH receptor in HLA-DR transgenic mice', Endocrinology, vol. 159, no. 9, pp. 3446-3457. https://doi.org/10.1210/en.2018-00306
Burton, BR, Tennant, RK, Love, J, Titball, RW, Wraith, DC & White, HN 2018, 'Variant proteins stimulate more IgM+ GC B-cells revealing a mechanism of cross-reactive recognition by antibody memory', Elife, vol. 7, e26832. https://doi.org/10.7554/eLife.26832
Şelli, ME, Thomas, AC, Wraith, D, Newby, AC & Wraith, D 2017, 'A humanized HLA-DR4 mouse model for autoimmune myocarditis', Journal of Molecular and Cellular Cardiology, vol. 107, pp. 22-26. https://doi.org/10.1016/j.yjmcc.2017.04.003
Şelli, ME, Wick, G, Wraith, D & Newby, AC 2017, 'Autoimmunity to HSP60 during diet induced obesity in mice', International Journal of Obesity, vol. 41, no. 2, pp. 348-351. https://doi.org/10.1038/ijo.2016.216
Mitchell, RE, Hassan, M, Burton, BR, Britton, G, Hill, EV, Verhagen, J, Wraith, DC & Wraith, D 2017, 'IL-4 enhances IL-10 production in Th1 cells: implications for Th1 and Th2 regulation', Scientific Reports, vol. 7, no. 1, 11315. https://doi.org/10.1038/s41598-017-11803-y
Wegner, A, Verhagen, J & Wraith, D 2017, 'Myeloid-derived suppressor cells mediate tolerance induction in autoimmune disease', Immunology. https://doi.org/10.1111/imm.12718
Britton, GJ, Ambler, R, Clark, DJ, Hill, EV, Tunbridge, HM, McNally, KE, Burton, BR, Butterweck, P, Sabatos-Peyton, C, Hampton-O'Neil, LA, Verkade, P, Wuelfing, C & Wraith, D 2017, 'PKCθ links proximal T cell and Notch signaling through localized regulation of the actin cytoskeleton', Elife, vol. 6, e20003. https://doi.org/10.7554/eLife.20003
Britton, GJ, Mitchell, RE, Burton, BR & Wraith, D 2017, 'Protein kinase C theta is required for efficient induction of IL-10-secreting T cells', PLoS ONE, vol. 12, no. 2, e0171547. https://doi.org/10.1371/journal.pone.0171547
Kishore, M, Cheung, KCP, Fu, H, Bonacina, F, Wang, G, Coe, D, Ward, EJ, Colamatteo, A, Jangani, M, Baragetti, A, Matarese, G, Smith, DM, Haas, R, Mauro, C, Wraith, D, Okkenhaug, K, Catapano, AL, De Rosa, V, Norata, GD & Marelli-Berg, FM 2017, 'Regulatory T cell migration is dependent on glucokinase-mediated glycolysis', Immunity, vol. 47, no. 5, pp. 875-889.e10. https://doi.org/10.1016/j.immuni.2017.10.017
Wraith, D 2017, 'The Future of Immunotherapy: A 20-Year Perspective', Frontiers in immunology, vol. 8, 01668. https://doi.org/10.3389/fimmu.2017.01668
Review article
Wraith, D 2018, 'Designing antigens for the prevention and treatment of autoimmune diseases', Current Opinion in Chemical Engineering, vol. 19, pp. 35-42. https://doi.org/10.1016/j.coche.2017.12.004
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