Recent publications
Article
Haroon, S, Nirantharakumar, K, Hughes, S, Subramanian, A, Aiyegbusi, OL, Davies, EH, Myles, PR, Williams, T, Turner, G, Chandan, J, McMullan, C, Lord, J, Wraith, D, McGee, K, Denniston, A, Taverner, T, Jackson, L, Sapey, E, Gkoutos, G, Gokhale, K, Leggett, E, Iles, C, Frost, C, McNamara, G, Bamford, A, Marshall, T, Zemedikun, D, Price, G, Marwaha, S, Simms-Williams, N, Brown, K, Walker, A, Jones, K, Matthews, K, Camaradou, J, Saint-Cricq , M, Kumar, S, Alder , Y, Stanton, DE, Agyen , L, Baber , M, Blaize , H & Calvert, M 2022, 'Therapies for Long COVID in non-hospitalised individuals: from symptoms, patient-reported outcomes and immunology to targeted therapies (The TLC Study)', BMJ open, vol. 12, no. 4, e060413. https://doi.org/10.1136/ bmjopen-2021-060413
Richardson, N & Wraith, DC 2021, 'Advancement of antigen-specific immunotherapy: knowledge transfer between allergy and autoimmunity', Immunotherapy Advances, vol. 1, no. 1, ltab009. https://doi.org/10.1093/immadv/ltab009
Elliot, T, Jennings, E, Lecky, D, Thawait, N, Flores-Langarica, A, Copland, A, Maslowski, K, Wraith, D & Bending, D 2021, 'Antigen and checkpoint receptor engagement recalibrates T cell receptor signal strength', Immunity, vol. 54, no. 11, pp. 2481-2496.e6. https://doi.org/10.1016/j.immuni.2021.08.020
Faustini, S, Jossi, S, Perez-Toledo, M, Shields, A, Allen, JD, Watanabe, Y, Newby, ML, Cook, A, Willcox, C, Salim, M, Goodall, M, Heaney, J, Marcial-Juarez, E, Morley, G, Torlinska, B, Wraith, D, Veenith, T, Harding, S, Jolles, S, Mark, PJ, Plant, T, Huissoon, A, O’Shea, MK, Willcox, B, Drayson, M, Crispin, M, Cunningham, A & Richter, A 2021, 'Development of a high-sensitivity ELISA detecting IgG, IgA and IgM antibodies to the SARS-CoV-2 spike glycoprotein in serum and saliva', Immunology. https://doi.org/10.1111/imm.13349
Richter, AG, Shields, AM, Karim, A, Birch, D, Faustini, SE, Steadman, L, Ward, K, Plant, T, Reynolds, G, Veenith, T, Cunningham, AF, Drayson, MT & Wraith, DC 2021, 'Establishing the prevalence of common tissue-specific autoantibodies following severe acute respiratory syndrome coronavirus 2 infection', Clinical and Experimental Immunology, vol. 205, no. 2, pp. 99-105. https://doi.org/10.1111/cei.13623
Shields, AM, Faustini, SE, Perez-Toledo, M, Jossi, S, Allen, JD, Al-Taei, S, Backhouse, C, Dunbar, LA, Ebanks, D, Emmanuel, B, Faniyi, AA, Garvey, M, Grinbergs, A, McGinnell, G, O'Neill, J, Watanabe, Y, Crispin, M, Wraith, DC, Cunningham, AF, Drayson, MT & Richter, AG 2021, 'Serological responses to SARS-CoV-2 following non-hospitalised infection: clinical and ethnodemographic features associated with the magnitude of the antibody response', BMJ Open Respiratory Research, vol. 8, no. 1, e000872. https://doi.org/10.1136/bmjresp-2020-000872
Shepard, ER, Wegner, A, Hill, EV, Burton, BR, Aerts, S, Schurgers, E, Hoedemaekers, B, Ng, STH, Streeter, HB, Jansson, L & Wraith, DC 2021, 'The Mechanism of Action of Antigen Processing Independent T Cell Epitopes Designed for Immunotherapy of Autoimmune Diseases', Frontiers in immunology, vol. 12, 654201. https://doi.org/10.3389/fimmu.2021.654201
Richardson, N, Ng, S & Wraith, D 2020, 'Antigen-specific immunotherapy for treatment of autoimmune liver diseases', Frontiers in immunology, vol. 11, 1586. https://doi.org/10.3389/fimmu.2020.01586
Bevington, SL, Ng, STH, Britton, GJ, Keane, P, Wraith, DC & Cockerill, PN 2020, 'Chromatin priming renders T cell tolerance-associated genes sensitive to activation below the signaling threshold for immune response genes', Cell Reports, vol. 31, no. 10, 107748. https://doi.org/10.1016/j.celrep.2020.107748
Faustini, SE, Jossi, SE, Perez-Toledo, M, Shields, A, Allen, JD, Watanabe, Y, Newby, ML, Cook, A, Willcox, CR, Salim, M, Goodall, M, Heaney, JL, Marcial-Juarez, E, Morley, GL, Torlinska, B, Wraith, DC, Veenith, T, Harding, S, Jolles, S, Mark, PJ, Plant, T, Huissoon, A, O'Shea, MK, Willcox, BE, Drayson, MT, Crispin, M, Cunningham, AF & Richter, AG 2020, 'Detection of antibodies to the SARS-CoV-2 spike glycoprotein in both serum and saliva enhances detection of infection', medRxiv. https://doi.org/10.1101/2020.06.16.20133025
Jennings, E, Elliot, T, Thawait, N, Kanabar, S, Yam-Puc, JC, Ono, M, Toellner, K-M, Wraith, DC, Anderson, G & Bending, D 2020, 'Nr4a1 and Nr4a3 reporter mice are differentially sensitive to T cell receptor signal strength and duration', Cell Reports, vol. 33, no. 5, 108328. https://doi.org/10.1016/j.celrep.2020.108328, https://doi.org/10.1016/j.celrep.2020.108328
Preprint
Lamerton, RE, Juarez, EM, Faustini, SE, Perez-Toledo, ME, Goodall, M, Jossi, SE, Newby, ML, Chapple, I, Dietrich, T, Veenith, T, Shields, AM, Harper, L, Henderson, IR, Rayes, J, Wraith, DC, Watson, SP, Crispin, M, Drayson, MT, Richter, AG & Cunningham, AF 2021 'In vitro, classical complement activation differs by disease severity and between SARS-CoV-2 antigens' medRxiv. https://doi.org/10.1101/2021.11.22.21266681
Review article
Schurgers, E & Wraith, DC 2021, 'Induction of Tolerance to Therapeutic Proteins With Antigen-Processing Independent T Cell Epitopes: Controlling Immune Responses to Biologics', Frontiers in immunology, vol. 12, 742695. https://doi.org/10.3389/fimmu.2021.742695
Wraith, DC & Krishna, MT 2021, 'Peptide allergen-specific immunotherapy for allergic airway diseases-State of the art', Clinical and Experimental Allergy . https://doi.org/10.1111/cea.13840
Working paper
Elliot, TAE, Jennings, EK, Lecky, DAJ, Thawait, N, Flores-Langarica, A, Wraith, DC & Bending, D 2021 'Antigen and checkpoint receptor recalibration of T cell receptor signal strength' bioRxiv, pp. 1-48. https://doi.org/10.1101/2021.03.02.431957
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