Recent publications
Article
Rauber, S, Mohammadian, H, Schmidkonz, C, Atzinger, A, Soare, A, Treutlein, C, Kemble, S, Mahony, CB, Geisthoff, M, Angeli, MR, Raimondo, MG, Xu, C, Yang, K-T, Lu, L, Labinsky, H, Saad, MSA, Gwellem, CA, Chang, J, Huang, K, Kampylafka, E, Knitza, J, Bilyy, R, Distler, JHW, Hanlon, MM, Fearon, U, Veale, DJ, Roemer, FW, Bäuerle, T, Maric, HM, Maschauer, S, Ekici, AB, Buckley, CD, Croft, AP, Kuwert, T, Prante, O, Cañete, JD, Schett, G & Ramming, A 2024, 'CD200+ fibroblasts form a pro-resolving mesenchymal network in arthritis', Nature Immunology. https://doi.org/10.1038/s41590-024-01774-4
Baruah, P, Mahony, C, Marshall, JL, Smith, CG, Monksfield, P, Irving, RI, Dumitriu, IE, Buckley, CD & Croft, AP 2024, 'Single-cell RNA sequencing analysis of vestibular schwannoma reveals functionally distinct macrophage subsets', British Journal of Cancer. https://doi.org/10.1038/s41416-024-02646-2
Murillo-Saich, JD, Coras, R, Ramirez, J, Quesada-Masachs, E, Sala-Climent, M, Eschelbach, K, Mahony, CB, Celis, R, Armando, A, Quehenberger, O, Croft, AP, Kavanaugh, A, Chang, E, Cañete, JD, Guma, M & Singh, A 2024, 'Synovial 5-LOX-derived oxylipins define a lympho-myeloid-enriched synovium', Arthritis & Rheumatology (Hoboken). https://doi.org/10.1002/art.42848
Ahmed, S, Mahony, CB, Torres, A, Murillo-Saich, J, Kemble, S, Cedeno, M, John, P, Bhatti, A, Croft, AP & Guma, M 2023, 'Dual inhibition of glycolysis and glutaminolysis for synergistic therapy of rheumatoid arthritis', Arthritis Research & Therapy, vol. 25, no. 1, 176. https://doi.org/10.1186/s13075-023-03161-0
Khan, AO, Rodriguez-Romera, A, Reyat, JS, Olijnik, AA, Colombo, M, Wang, G, Wen, WX, Sousos, N, Murphy, LC, Grygielska, B, Perrella, G, Mahony, CB, Ling, RE, Elliott, NE, Karali, CS, Stone, AP, Kemble, S, Cutler, EA, Fielding, AK, Croft, AP, Bassett, D, Poologasundarampillai, G, Roy, A, Gooding, S, Rayes, J, Machlus, KR & Psaila, B 2023, 'Human Bone Marrow Organoids for Disease Modeling, Discovery, and Validation of Therapeutic Targets in Hematologic Malignancies', Cancer Discovery, vol. 13, no. 2, pp. 364-385. https://doi.org/10.1158/2159-8290.CD-22-0199
Reyat, JS, di Maio, A, Grygielska, B, Pike, J, Kemble, S, Rodriguez-Romero, A, Simoglou Karali, C, Croft, AP, Psaila, B, Simões, F, Rayes, J & Khan, AO 2023, 'Modelling the pathology and treatment of cardiac fibrosis in vascularised atrial and ventricular cardiac microtissues', Frontiers in cardiovascular medicine, vol. 10. https://doi.org/10.3389/fcvm.2023.1156759
Torres, A, Kang, S, Mahony, CB, Cedeño, M, Oliveira, PG, Fernandez-Bustamante, M, Kemble, S, Laragione, T, Gulko, PS, Croft, AP, Sanchez-Lopez, E, Miyamoto, S & Guma, M 2023, 'Role of mitochondria-bound HK2 in rheumatoid arthritis fibroblast-like synoviocytes', Frontiers in immunology, vol. 14, 1103231. https://doi.org/10.3389/fimmu.2023.1103231
Korsunsky, I, Wei, K, Pohin, M, Kim, EY, Barone, F, Major, T, Taylor, E, Ravindran, R, Kemble, S, Watts, GFM, Jonsson, AH, Jeong, Y, Athar, H, Windell, D, Kang, JB, Friedrich, M, Turner, J, Nayar, S, Fisher, BA, Raza, K, Marshall, JL, Croft, AP, Tamura, T, Sholl, LM, Vivero, M, Rosas, IO, Bowman, SJ, Coles, M, Frei, AP, Lassen, K, Filer, A, Powrie, F, Buckley, CD, Brenner, MB & Raychaudhuri, S 2022, 'Cross-tissue, single-cell stromal atlas identifies shared pathological fibroblast phenotypes in four chronic inflammatory diseases', Med, vol. 3, no. 7, pp. 481-518. https://doi.org/10.1016/j.medj.2022.05.002
Fenton, C, Martin, C, Jones, R, Croft, A, Campos, J, Naylor, A, Taylor, A, Chimen, M, Cooper, M, Lavery, G, Raza, K & Hardy, R 2021, 'Local steroid activation is a critical mediator of the anti-inflammatory actions of therapeutic glucocorticoids', Annals of the Rheumatic Diseases, vol. 80, no. 2, pp. 250-260. https://doi.org/10.1136/annrheumdis-2020-218493
Comment/debate
Bolton, C & Croft, AP 2024, 'All fibroblasts are equal, but some are more equal than others', Nature Reviews Rheumatology. https://doi.org/10.1038/s41584-024-01097-6
Hackland, A & Croft, AP 2023, 'Are the origins of adult arthritis seeded during embryonic development?', Nature Reviews Rheumatology, vol. 19, no. 3, pp. 132-133. https://doi.org/10.1038/s41584-023-00911-x
Editorial
Alegria, GC & Croft, AP 2022, 'Fibroblasts, a target for imaging and therapeutics in rheumatoid arthritis', Rheumatology, vol. 61, no. 7. https://doi.org/10.1093/rheumatology/keab845
Review article
CLUSTER Consortium, Wedderburn, LR, Ramanan, AV, Croft, AP, Hyrich, KL & Dick, AD 2022, 'Towards molecular-pathology informed clinical trials in childhood arthritis to achieve precision medicine in juvenile idiopathic arthritis', Annals of the Rheumatic Diseases. https://doi.org/10.1136/ard-2022-222553
Kemble, S & Croft, AP 2021, 'Critical Role of Synovial Tissue-Resident Macrophage and Fibroblast Subsets in the Persistence of Joint Inflammation', Frontiers in immunology, vol. 12, 715894. https://doi.org/10.3389/fimmu.2021.715894
Marsh, L-J, Kemble, S, Reis Nisa, P, Singh, R & Croft, AP 2021, 'Fibroblast pathology in inflammatory joint disease', Immunological Reviews, vol. 302, no. 1, pp. 163-183. https://doi.org/10.1111/imr.12986
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