Recent publications
Article
Logan, A, Nagy, Z, Barnes, N, Belli, T, Di Pietro, V, Tavazzi, B, Lazzarino, G, Lazzarino, G, Bruce, L & Persson, LI 2022, 'A phase II open label clinical study of the safety, tolerability and efficacy of ILB® for amyotrophic lateral sclerosis', PLOS One, vol. 17, no. 5, e0267183. <http://10.1371/journal.pone.0267183>
Lazzarino, G, Mangione, R, Belli, A, Di Pietro, V, Nagy, Z, Barnes, NM, Bruce, L, Ropero, BM, Persson, LI, Manca, B, Saab, MW, Amorini, AM, Tavazzi, B, Lazzarino, G & Logan, A 2021, 'ILB® attenuates clinical symptoms and serum biomarkers of oxidative/nitrosative stress and mitochondrial dysfunction in patients with Amyotrophic Lateral Sclerosis', Journal of Personalized Medicine, vol. 11, no. 8, 794. https://doi.org/10.3390/jpm11080794
Robinson, J, Whitworth, K, Jinks, E, Nagy, Z, Bicknell, R & Lee, S 2020, 'An evaluation of the tumour endothelial marker CLEC14A as a therapeutic target in solid tumours', Journal of Pathology: Clinical Research, vol. 6, no. 4, pp. 308-319. https://doi.org/10.1002/cjp2.176
Zhuang, X, Maione, F, Robinson, J, Bentley, M, Kaul, B, Whitworth, K, Jumbu, N, Jinks, E, Bystrom, J, Gabriele, P, Garibaldi, E, Delmastro, E, Nagy, Z, Gilham, D, Giraudo, E, Bicknell, R & Lee, S 2020, 'CAR T-cells targeting tumor endothelial marker CLEC14A inhibit tumor growth', JCI Insight, vol. 5, no. 19, e138808. https://doi.org/10.1172/jci.insight.138808
Frumento, G, Verma, K, Croft, W, White, A, Zuo, J, Nagy, Z, Kissane, S, Anderson, G, Moss, P & Chen, FE 2020, 'Homeostatic Cytokines Drive Epigenetic Reprogramming of Activated T Cells into a "Naive-Memory" Phenotype', iScience, vol. 23, no. 4, 100989. https://doi.org/10.1016/j.isci.2020.100989
Lazzarino, G, Amorini, AM, Barnes, NM, Bruce, L, Mordente, A, Lazzarino, G, Pietro, VD, Tavazzi, B, Belli, A, Logan, A & Nagy, Z 2020, 'Low molecular weight dextran sulfate (ILB®) administration restores brain energy metabolism following severe traumatic brain injury in the rat', Antioxidants, vol. 9, no. 9, 850. https://doi.org/10.3390/antiox9090850
Trevino, V, Cassese, A, Nagy, Z, Zhuang, X, Herbert, J, Antzack, P, Clarke, K, Davies, N, Rahman, A, Campbell, MJ, Guindani, M, Bicknell, R, Vannucci, M & Falciani, F 2016, 'A Network Biology Approach Identifies Molecular Cross-Talk between Normal Prostate Epithelial and Prostate Carcinoma Cells', PLoS Computational Biology, vol. 12, no. 4, e1004884. https://doi.org/10.1371/journal.pcbi.1004884
Zhuang, X, Ahmed, F, Zhang, Y, Ferguson, H, Steele, JC, Steven, NM, Nagy, Z, Heath, VL, Toellner, K-M & Bicknell, R 2015, 'Robo4 vaccines induce antibodies that retard tumor growth', Angiogenesis, vol. 18, no. 1, pp. 83-95. https://doi.org/10.1007/s10456-014-9448-z
Yates, SC, Zafar, A, Rabai, EM, Foxall, JB, Morrison, K, Nagy, S, Clarke, C, Esiri, MM, Christie, S, Smith, AD & Nagy, Z 2015, 'The effects of two polymorphisms on p21cip1 function and their association with Alzheimer's disease in a population of European descent', PLoS ONE, vol. 10, no. 1, e0114050. https://doi.org/10.1371/journal.pone.0114050
Lu, X, Boora, U, Seabra, L, Rabai, EM, Fenton, J, Reiman, A, Nagy, Z & Maher, ER 2014, 'Knockdown of Slingshot 2 (SSH2) serine phosphatase induces Caspase3 activation in human carcinoma cell lines with the loss of the Birt-Hogg-Dubé tumour suppressor gene (FLCN)', Oncogene, vol. 33, no. 8, pp. 956-65. https://doi.org/10.1038/onc.2013.27
Tull, S, Verissimo, A, Heath, V, Yates, S, Nagy, Z & Bicknell, R 2014, 'The potential role of ECSCR in vessel development and tumour progression', Angiogenesis, vol. 17, no. 3, pp. 772-772.
Abstract
Zhuang, X, Kaul, B, Bentley, M, Nagy, Z, Giraudo, E, Bendle, G, Gilham, D, Bicknell, R & Lee, SP 2014, 'Immunotherapy using genetically modified T lymphocytes to target CLEC14A on the tumor vasculature', Cancer Research, vol. 74, no. 19 Suppl. https://doi.org/10.1158/1538-7445.AM2014-LB-256
Other contribution
Barrett, T & Nagy, Z 2015, Sodium Valproate for the treatment of Wolfram syndrome EU/3/14/1428..
Patent
Tucker, J, Pikramenou, Z, Beggs, A, Nagy, Z & Chakrabarti, P May. 07 2019, Sensor WO2019043353A1: WO2019043353A1, Patent No. WO2019043353A1.
Nagy, Z & Barrett, T Mar. 03 2014, TREATMENT OF WOLFRAM SYNDROME-RELATED NEURODEGENERATION, Patent No. WO2014/049366.
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