Dr Dhruv Parekh BMedSci (Hons) MBBS(Hons) PhD MRCP

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Institute of Inflammation and Ageing
Clinical Lecturer in Respiratory Medicine

Contact details

Address
Institute of Inflammation and Ageing
College of Medical and Dental Sciences
Centre for Translational and Inflammatory Research
1st Floor, New Queen Elizabeth Hospital
Mindelsohn Way
Birmingham, B15 2WB

Dr Dhruv Parekh is a Clinical Lecturer in Respiratory Medicine at the University of Birmingham and advanced trainee in Intensive Care Medicine in the final stages of clinical training within the West Midlands Deanery. His research interests are developing novel therapies in ARDS, perioperative inflammation, sepsis and critical care.

Qualifications

  • PhD (Health Sciences), University of Warwick, 2016
  • MRCP (UK), Royal College of Physicians, 2007
  • MBBS (Hons), St Bartholomew’s and the Royal London School of Medicine, 2003
  • BMedSci (Hons), St Bartholomew’s and the Royal London School of Medicine, 2002

Biography

Dr Dhruv Parekh completed his medical training at St Bartholomew’s and the Royal London School of Medicine in 2003. He gained a 1st class honours intercalated bachelor in medical sciences and won numerous prizes and award during his undergraduate training. After initial training and successful completion of his post-graduate exams he commenced clinical training in Respiratory, General Internal and Intensive Care Medicine.

Dhruv was awarded a highly competitive MRC Clinical Research Training Fellowship and his PhD investigated if vitamin D deficiency is a mechanistic driver of ARDS, which was completed in collaboration with the Universities of Birmingham and Warwick and the West Midlands ARDS network. 

He is currently a Clinical Lecturer in Respiratory Medicine at the University of Birmingham and also a member of the Perioperative, Anaesthesia, Critical Care and Trauma Trials (PACCT) group. He is currently in the final stages of his specialist training.

Dhruv has contributed to clinical trials and translational studies of vitamin D to prevent ARDS and statins in pneumonia and sepsis. He contributes to supervising BMedSci students and teaching respiratory modules on the MBChB course at the University. He has presented at many national and international meetings and has been the holder of the American Thoracic Society International Trainee Scholarship in 2014.

Teaching

Teaching Programmes

  • MBChB
    • 1st Year MBChB Respiratory (IRM) Module
    • Tutor and Lecturer for the Written Professional Communication module year 5
    • Research tasters for students
  • BMedSc student supervision
  • Offers Personal Interest Projects: Respiratory and ICM

Postgraduate supervision

Dhruv is interested in supervising doctoral research students who are interested in research in the field of respiratory, peri-operative medicine and critical care.

If you are interested in studying any of these subject areas please contact Dhruv on the contact details above, or for any general doctoral research enquiries, please email: dr@contacts.bham.ac.uk or call +44 (0)121 414 5005.

For a full list of available Doctoral Research opportunities, please visit our Doctoral Research programme listings.

Research

Dhruv has translational research interests in respiratory, peri-operative and intensive care medicine. He is passionate about bringing the bench to bedside and his main research focuses on investigating novel therapeutic targets and increasing the understanding of the mechanisms of injury involved in sepsis and ARDS. His cellular interests have developed in the area of innate immunity and specifically macrophage and monocyte biology and function.

Publications

Muthuri SG, Venkatesan S, Myles PR, Leonardi-Bee J, Lim WS, Mamun AA, Anovadiya AP, Araújo WN, Azziz-Baumgartner E, Báez C, Bantar C, Barhoush MM, Bassetti M, Beovic B, Bingisser R, Bonmarin I, Borja-Aburto VH, Cao B, Carratala J, Cuezzo MR, Denholm JT, Dominguez SR, Duarte PA, Dubnov-Raz G, Echavarria M, Fanella S, Fraser J, Gao Z, Gérardin P, Giannella M, Gubbels S, Herberg J, Iglesias AL, Hoeger PH, Hoffmann M, Hu X, Islam QT, Jiménez MF, Kandeel A, Keijzers G, Khalili H, Khandaker G, Knight M, Kusznierz G, Kuzman I, Kwan AM, Amine IL, Langenegger E, Lankarani KB, Leo YS, Linko R, Liu P, Madanat F, Manabe T, Mayo-Montero E, McGeer A, Memish ZA, Metan G, Mikić D, Mohn KG, Moradi A, Nymadawa P, Ozbay B, Ozkan M, Parekh D, Paul M, Poeppl W, Polack FP, Rath BA, Rodríguez AH, Siqueira MM, Skręt-Magierło J, Talarek E, Tang JW, Torres A, Törün SH, Tran D, Uyeki TM, van Zwol A, Vaudry W, Velyvyte D, Vidmar T, Zarogoulidis P; PRIDE Consortium Investigators and Nguyen-Van-Tam JS (2016) Impact of neuraminidase inhibitors on influenza A(H1N1)pdm09-related pneumonia: an IPD meta-analysis. Influenza Other Respir Viruses 10(3):192-204

Dancer RC, Parekh D, Lax S, D'Souza V, Zheng S, Bassford CR, Park D, Bartis DG, Mahida R, Turner AM, Sapey E, Wei W, Naidu B, Stewart PM, Fraser WD, Christopher KB, Cooper MS, Gao F, Sansom DM, Martineau AR, Perkins GD and Thickett DR (2015) Vitamin D deficiency contributes directly to the acute respiratory distress syndrome (ARDS). Thorax 70(7):617-24

Glasgow AM, Small DM, Scott A, McLean DT, Camper N, Hamid U, Hegarty S, Parekh D, O'Kane C, Lundy FT, McNally P, Elborn JS, McAuley DF, Weldon S and Taggart CC (2015) A role for whey acidic protein four-disulfide-core 12 (WFDC12) in the regulation of the inflammatory response in the lung. Thorax 70(5):426-32

Johnstone J, Hobbins S, Parekh D and O'Hickey S (2015) Excess subcutaneous tissue may preclude intramuscular delivery when using epinephrine autoinjectors in patients with anaphylaxis. Allergy 70(6):703-6

Greenwood H, Patel J, Mahida R, Wang Q, Parekh D, Dancer RC, Khiroya H, Sapey E and Thickett DR (2014) Simvastatin to modify neutrophil function in older patients with septic pneumonia (SNOOPI): study protocol for a randomised placebo-controlled trial. Trials 15:332

Parekh D, Dancer RC and Thickett DR (2104) Alternatives to animal research in acute lung injury. BMJ 349:g4171

Muthuri SG, Venkatesan S, Myles PR, Leonardi-Bee J, Al Khuwaitir TS, Al Mamun A, Anovadiya AP, Azziz-Baumgartner E, Báez C, Bassetti M, Beovic B, Bertisch B, Bonmarin I, Booy R, Borja-Aburto VH, Burgmann H, Cao B, Carratala J, Denholm JT, Dominguez SR, Duarte PA, Dubnov-Raz G, Echavarria M, Fanella S, Gao Z, Gérardin P, Giannella M, Gubbels S, Herberg J, Iglesias AL, Hoger PH, Hu X, Islam QT, Jiménez MF, Kandeel A, Keijzers G, Khalili H, Knight M, Kudo K, Kusznierz G, Kuzman I, Kwan AM, Amine IL, Langenegger E, Lankarani KB, Leo YS, Linko R, Liu P, Madanat F, Mayo-Montero E, McGeer A, Memish Z, Metan G, Mickiene A, Mikić D, Mohn KG, Moradi A, Nymadawa P, Oliva ME, Ozkan M, Parekh D, Paul M, Polack FP, Rath BA, Rodríguez AH, Sarrouf EB, Seale AC, Sertogullarindan B, Siqueira MM, Skręt-Magierło J, Stephan F, Talarek E, Tang JW, To KK, Torres A, Törün SH, Tran D, Uyeki TM, Van Zwol A, Vaudry W, Vidmar T, Yokota RT, Zarogoulidis P; PRIDE Consortium Investigators and Nguyen-Van-Tam JS (2014) Effectiveness of neuraminidase inhibitors in reducing mortality in patients admitted to hospital with influenza A H1N1pdm09 virus infection: a meta-analysis of individual participant data. Lancet Respir Med 2(5):395-404

Parekh D, Lax S, Dancer RCA, Perkins GD and Thickett DR (2014) Vitamin D deficiency and bacterial load in a murine model of sepsis-induced lung injury. The Lancet 383:S15

Parekh D, Thickett DR and Turner AM (2013) Vitamin D Deficiency and Acute Lung Injury. Inflamm Allergy Drug Targets 12(4):253-61

Parekh D, Dancer RC, Lax S, Cooper MS, Martineau AR, Fraser WD, Tucker O, Alderson D, Perkins GD, Gao-Smith F and Thickett DR (2013) Vitamin D to prevent acute lung injury following oesophagectomy (VINDALOO): study protocol for a randomised placebo controlled trial. Trials 14(1):100

Parekh D, Dancer RC and Thickett DR (2011) Acute Lung Injury. Clin Med (Lond) 11(6):615–8

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