Dr Majid Malboubi is a lecturer in the Department of Mechanical Engineering in the School of Engineering.
Inspired by the workings of nature, he applies the principles of mechanics and design micro-tools to unravel the physics underlying cellular processes and to understand how cells interact with their surroundings. For his PhD at the University of Birmingham, he worked on the interaction of biological membranes with solid substrates, and published several articles on this subject, as well as a book (Gigaseal formation in patch clamping, Springer, 2014).
Upon moving to the London Centre of Nanotechnology at UCL, he worked on the poroelasticity and pressure propagation in cells to explain cells’ ability to sustain transient and prolonged pressure gradients across their cytoplasm in response to extrinsic and intrinsic mechanical stresses. He also developed several microfluidic devices for cancer metastasis and drug screening. Dr Malboubi subsequently moved to the University of Oxford to investigate the effects of mechanical loadings, such as compression or stretch on neural electrophysiological responses and the ability of neurons to fire action potentials after trauma.