Dr Majid Malboubi PhD

Dr Majid Malboubi

Department of Mechanical Engineering
Lecturer

Contact details

Address
Department of Mechanical Engineering
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Dr Majid Malboubi is a lecturer in the Department of Mechanical Engineering in the School of Engineering.

Inspired by the workings of nature, he applies the principles of mechanics and design micro-tools to unravel the physics underlying cellular processes and to understand how cells interact with their surroundings. For his PhD at the University of Birmingham, he worked on the interaction of biological membranes with solid substrates, and published several articles on this subject, as well as a book (Gigaseal formation in patch clamping, Springer, 2014).

Upon moving to the London Centre of Nanotechnology at UCL, he worked on the poroelasticity and pressure propagation in cells to explain cells’ ability to sustain transient and prolonged pressure gradients across their cytoplasm in response to extrinsic and intrinsic mechanical stresses. He also developed several microfluidic devices for cancer metastasis and drug screening. Dr Malboubi subsequently moved to the University of Oxford to investigate the effects of mechanical loadings, such as compression or stretch on neural electrophysiological responses and the ability of neurons to fire action potentials after trauma.

Qualifications

  • Lecturer, Department of Mechanical Engineering, University of Birmingham (2018)
  • Postdoctoral Researcher, Department of Engineering Science, University of Oxford (2014 – 2018)
  • Postdoctoral Researcher, London Centre for Nanotechnology, University College London (2011 – 2014)
  • PhD in Mechanical Engineering, University of Birmingham (2007 – 2011)

Teaching

  •   Mechanics
  • Fluid Mechanics
  • Energy Transfer and Thermodynamics
  • Mechanics Laboratory
  • Fluid Mechanics Laboratory

Research

  • Cell and tissue mechanics
  • Microfluidics for life sciences
  • Patch clamp electrophysiology
  • Substrate-Membrane interactions

Publications

For a full list of publications, please visit Majid's google scholar page:

Book

Book Chapter

Peer Reviewed Journal Articles

Peer Reviewed Conference Papers

  • Malboubi M, Ostadi H, Wang S, Gu Y, Jiang K. The effect of pipette tip roughness on gigaseal formation. The 2009 International Conference of Systems Biology and Bioengineering, World Congress on Engineering. 1-3 July 2009 London. 1849-1852.
  • Malboubi M, Shakeri M, Bakhshi M. Design and fabrication of a prototype two-component strain gauge based grinding dynamometer. International Conference on Advances in Materials and Processing Technologies, 30 July - 01 August 2006 Las Vegas
  • Malboubi M, and Shakeri M. Machine tools with parallel structure and their calibration methods. The 13th International Conference on Mechanical Engineering, 17-19 May 2005 Esfahan
  • Malboubi M, Jerusalem A. Experimental multi-physics measurement of neuronal responses under trauma, Biophysical Journal, 110(2), 149a, 2016
  • Malboubi M, Jayo A, Parsons M, Charras M. An open access microfluidic device for the study of cancer cell deformation during migration. 40th International Conference on Micro Nano Engineering, 22 – 26 September 2014, Lausanne
  • Bove A, Malboubi M, Lowe A, Charras G. A microfluidic device for studying cancer cells competition under controlled conditions. 40th International Conference on Micro Nano Engineering, 22 – 26 September 2014, Lausanne
  • Davies J, Malboubi M, Ivetic A, Charras G. A microfluidic chip to model leukocyte inflammatory responses. 40th International Conference on Micro Nano Engineering, 22-26 September 2014, Lausanne
  • Malboubi M, Behroozi M, Bowen J, Chizari M, Charras G, Jiang K. The effect of aperture size on gigaseal formation. Biophysical Journal, 104(2), 673a, 2013
  • Malboubi M, Gu Y, Jiang K. Surface property characterization of glass micropipettes using SEM stereoscopic technique. 36th International Conference on Micro Nano Engineering, 19-22 September 2010 Genoa
  • Mohammadkhani M, Malboubi M, Anthony C, Jiang K. 3D-reconstruction of nanostructures made by nanosphere lithography using SEM stereoscopic technique. 36th International Conference on Micro Nano Engineering, 19-22 September 2010 Genoa
  • Malboubi M, Gu Y, Jiang K. Investigation of pipette roughness effects on seal formation in patch clamping. 35th International Conference on Micro Nano Engineering, 28 September - 01 October 2009 Ghent
  • Ostadi H, Malboubi M, Jiang K, Prewett P. FIB/SEM Nano-Tomography of a micropipette. 34th International Conference on Micro Nano Engineering, 15-18 September 2008 Athens

View all publications in research portal