Recent publications
Article
Barnard, L, Schiffer, L, Du-Toit, RL, Tamblyn, J, Chen, S, Africander, D, Arlt, W, Foster, P & Storbeck, K-H 2021, '11-oxygenated estrogens are a novel class of human estrogens but do not contribute to the circulating estrogen pool', Endocrinology, vol. 162, no. 3, bqaa231. https://doi.org/10.1210/endocr/bqaa231
El-gamal, MI, Zaraei, S, Foster, PA, Anbar, HS, El-gamal, R, El-awady, R & Potter, BVL 2020, 'A new series of aryl sulfamate derivatives: design, synthesis, and biological evaluation', Bioorganic & Medicinal Chemistry, vol. 28, no. 8, 115406. https://doi.org/10.1016/j.bmc.2020.115406
Grienke, U, Foster, P, Zwirchmayr, J, Tahir, A, Rollinger, JM & Mikros, E 2019, '1H NMR-MS-based heterocovariance as a drug discovery tool for fishing bioactive compounds out of a complex mixture of structural analogues.', Scientific Reports, vol. 9, 11113. https://doi.org/10.1038/s41598-019-47434-8
Grienke, U, Kaserer, T, Kirchweger, B, Lambrinidis, G, Kandel, RT, Foster, P, Schuster, D, Mikros, E & Rollinger, JM 2019, 'Steroid sulfatase inhibiting lanostane triterpenes – structure activity relationship and in silico insights', Bioorganic Chemistry, vol. 95, 103495. https://doi.org/10.1016/j.bioorg.2019.103495
Moi, D, Foster, P, Rimmer, L, Jaffri, A, Deplano, A, Balboni, G, Onnis, V & Potter, BVL 2019, 'Synthesis and in vitro evaluation of piperazinyl-ureido sulfamates as steroid sulfatase inhibitors', European Journal of Medicinal Chemistry, vol. 182, 111614. https://doi.org/10.1016/j.ejmech.2019.111614
Meimaridou, E, Goldsworthy, M, Chortis, V, Fragouli, E, Foster, PA, Arlt, W, Cox, R & Metherell, LA 2018, 'NNT is a key regulator of adrenal redox homeostasis and steroidogenesis in male mice', Journal of Endocrinology, vol. 236, pp. 13-28. https://doi.org/10.1530/JOE-16-0638
Chortis, V, Taylor, A, Doig, C, Walsh, M, Meimaridou, E, Jenkinson, C, Rodriguez Blanco, G, Ronchi, C, Jaffri, A, Metherell, LA, Hebenstreit, D, Dunn, W, Arlt, W & Foster, P 2018, 'Nicotinamide nucleotide transhydrogenase as a novel treatment target in adrenocortical carcinoma', Endocrinology, vol. 159, no. 8, pp. 2836–2849. https://doi.org/10.1210/en.2018-00014
Gibson, DA, Foster, P, Simitsidellis, I, Critchley, HOD, Kelepouri, O, Collins, F & Saunders, PTK 2018, 'Sulfation pathways: a role for steroid sulfatase in intracrine regulation of endometrial decidualisation', Journal of Molecular Endocrinology, vol. 61, no. 2, pp. M57-M65. https://doi.org/10.1530/JME-18-0037
Gilligan, L, Rahman, H, Hewitt, A-M, Sitch, A, Gondal, A, Arvaniti, A, Taylor, A, Read, M, Morton, D & Foster, P 2017, 'Estrogen activation by steroid sulfatase increases colorectal cancer proliferation via GPER', Journal of Clinical Endocrinology and Metabolism, vol. 102, no. 12, pp. 4435-4447. https://doi.org/10.1210/jc.2016-3716
Gilligan, L, Gondal, A, Tang, V, Hussain, MT, Arvaniti, A, Hewitt, A-M & Foster, PA 2017, 'Estrone sulfate transport and steroid sulfatase activity in colorectal cancer: implications for Hormone Replacement Therapy', Frontiers in Pharmacology, vol. 8, 103. https://doi.org/10.3389/fphar.2017.00103
Dohle, W, Jourdan, FL, Menchon, G, Prota, AE, Foster, PA, Mannion, P, Hamel, E, Thomas, MP, Kasprzyk, PG, Ferrandis, E, Steinmetz, MO, Leese, MP & Potter, BVL 2017, 'Quinazolinone-based Anticancer Agents: Synthesis, Anti-proliferative SAR, Anti-tubulin Activity and Tubulin Co-crystal Structure', Journal of Medicinal Chemistry. https://doi.org/10.1021/acs.jmedchem.7b01474
El-Gamal, M, Semreen, M, Foster, P & Potter, B 2016, 'Design, synthesis, and biological evaluation of new arylamide derivatives possessing sulfonate or sulfamate moieties as steroid sulfatase enzyme inhibitors', Bioorganic & Medicinal Chemistry, vol. 24, no. 12. https://doi.org/10.1016/j.bmc.2016.04.040
Rahman, H-U, Hofland, J & Foster, P 2016, 'In Touch with your Feminine Side: How Oestrogen Metabolism Impacts Prostate Cancer', Endocrine-related cancer. https://doi.org/10.1530/ERC-16-0118
Editorial
Mueller, J & Foster, P 2018, 'Steroid Sulfation Research has come a long way', Journal of Molecular Endocrinology, vol. 61, no. 2, pp. E1-E2. https://doi.org/10.1530/JME-18-0109
Review article
Foster, P & Mueller, JW 2018, 'Sulfation pathways: Insights into steroid sulfation and desulfation pathways', Journal of Molecular Endocrinology, vol. 61, no. 2, pp. T271–T283. https://doi.org/10.1530/JME-18-0086
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