Recent publications
Article
Foster, PA & Mueller, JW 2023, 'New structural insights provide a different angle on steroid sulfatase action', The Journal of Steroid Biochemistry and Molecular Biology, vol. 232, 106353. https://doi.org/10.1016/j.jsbmb.2023.106353
Eissa, AG, Powell, L, Gee, J, Foster, P & Simons, C 2023, 'Pyridine based dual binding site aromatase (CYP19A1) inhibitors', RSC Medicinal Chemistry. https://doi.org/10.1039/D2MD00352J
Dohle, W, Asiki, H, Gruchot, W, Foster, P, Sahota, H, Bai, R, Kirsten, C, Hamel, E & Potter, BVL 2022, '2-difluoromethoxy-substituted estratriene sulfamates: synthesis, antiproliferative SAR, antitubulin activity, and steroid sulfatase inhibition', ChemMedChem. https://doi.org/10.1002/cmdc.202200408
Eissa, AG, Barrow, D, Gee, J, Powell, L, Foster, P & Simons, C 2022, '4th Generation nonsteroidal aromatase inhibitors: An iterative SAR-guided design, synthesis, and biological evaluation towards picomolar dual binding inhibitors', European Journal of Medicinal Chemistry, vol. 240, 114569. https://doi.org/10.1016/j.ejmech.2022.114569
Barnard, L, Schiffer, L, Du-Toit, RL, Tamblyn, J, Chen, S, Africander, D, Arlt, W, Foster, P & Storbeck, K-H 2021, '11-oxygenated estrogens are a novel class of human estrogens but do not contribute to the circulating estrogen pool', Endocrinology, vol. 162, no. 3, bqaa231. https://doi.org/10.1210/endocr/bqaa231
Powell, L & Foster, P 2021, 'Protein disulphide isomerase inhibition as a potential cancer therapeutic strategy', Cancer Medicine, vol. 10, no. 8, pp. 2812-2825. https://doi.org/10.1002/cam4.3836
Mueller, JW, Vogg, N, Lightning, TA, Weigand, I, Ronchi, C, Foster, P & Kroiss, M 2021, 'Steroid sulfation in adrenal tumors', Journal of Clinical Endocrinology and Metabolism, vol. 2021, no. 00, dgab182, pp. 3385-3397. https://doi.org/10.1210/clinem/dgab182
El-gamal, MI, Zaraei, S, Foster, PA, Anbar, HS, El-gamal, R, El-awady, R & Potter, BVL 2020, 'A new series of aryl sulfamate derivatives: design, synthesis, and biological evaluation', Bioorganic & Medicinal Chemistry, vol. 28, no. 8, 115406. https://doi.org/10.1016/j.bmc.2020.115406
Grienke, U, Foster, P, Zwirchmayr, J, Tahir, A, Rollinger, JM & Mikros, E 2019, '1H NMR-MS-based heterocovariance as a drug discovery tool for fishing bioactive compounds out of a complex mixture of structural analogues.', Scientific Reports, vol. 9, 11113. https://doi.org/10.1038/s41598-019-47434-8
Grienke, U, Kaserer, T, Kirchweger, B, Lambrinidis, G, Kandel, RT, Foster, P, Schuster, D, Mikros, E & Rollinger, JM 2019, 'Steroid sulfatase inhibiting lanostane triterpenes – structure activity relationship and in silico insights', Bioorganic Chemistry, vol. 95, 103495. https://doi.org/10.1016/j.bioorg.2019.103495
Moi, D, Foster, P, Rimmer, L, Jaffri, A, Deplano, A, Balboni, G, Onnis, V & Potter, BVL 2019, 'Synthesis and in vitro evaluation of piperazinyl-ureido sulfamates as steroid sulfatase inhibitors', European Journal of Medicinal Chemistry, vol. 182, 111614. https://doi.org/10.1016/j.ejmech.2019.111614
Meimaridou, E, Goldsworthy, M, Chortis, V, Fragouli, E, Foster, PA, Arlt, W, Cox, R & Metherell, LA 2018, 'NNT is a key regulator of adrenal redox homeostasis and steroidogenesis in male mice', Journal of Endocrinology, vol. 236, pp. 13-28. https://doi.org/10.1530/JOE-16-0638
Chortis, V, Taylor, A, Doig, C, Walsh, M, Meimaridou, E, Jenkinson, C, Rodriguez Blanco, G, Ronchi, C, Jaffri, A, Metherell, LA, Hebenstreit, D, Dunn, W, Arlt, W & Foster, P 2018, 'Nicotinamide nucleotide transhydrogenase as a novel treatment target in adrenocortical carcinoma', Endocrinology, vol. 159, no. 8, pp. 2836–2849. https://doi.org/10.1210/en.2018-00014
Review article
Banibakhsh, A, Sidhu, D, Khan, S, Haime, H & Foster, PA 2023, 'Sex steroid metabolism and action in colon health and disease', The Journal of Steroid Biochemistry and Molecular Biology, vol. 233, 106371. https://doi.org/10.1016/j.jsbmb.2023.106371
Foster, P 2021, 'Steroid sulphatase and its inhibitors: past, present and future', Molecules, vol. 26, no. 10, 2852. https://doi.org/10.3390/molecules26102852
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