Dr Tamara Miljus

Tamara Miljus

Institute of Metabolism and Systems Research
Postdoctoral Research Fellow

Contact details

Office 329, IBR
University of Birmingham
B15 2TT

Tamara is a postdoctoral research fellow in the group of Professor Davide Calebiro. She is using fluorescence-based single-molecule microscopy to study dynamics of interactions between G protein-coupled receptors (GPCRs) and arrestins.


  • Doctor of Sciences, ETH Zurich, Switzerland, 2018
  • MSc in Chemistry, fields biochemistry and organic chemistry, University of Zagreb, Croatia, 2015
  • BSs in Chemistry, University of Zagreb, Croatia, 2013


Prior to joining IMSR, Tamara completed her PhD at the Paul Scherrer Institute in Switzerland, investigating molecular mechanisms of biased signalling in cannabinoid CB2 receptor. During PhD, she spent 8 months in Professor Michel Bouvier’s lab at the University of Montreal using BRET-based biosensors in live cells to assess signalling of cannabinoid receptors, including high-throughput ligand and mutant screens.


Tippett DN, Hoare B, Miljus T, Sykes DA, Veprintsev DB. ThermoFRET: A novel nanoscale G protein coupled receptor thermostability assay functional in crude solubilised membrane preparations. BioRxiv Preprint (2020)

Miljus T, Sykes DA, Harwood CR, Vuckovic Z, Veprintev DB. GPCR Solubilization and Quality Control. Methods Mol Biol 2127 (2020) 105-127

Heydenreich FM*, Miljuš T*, Milić D, Veprintsev DB. High-throughput Site-directed Scanning Mutagenesis Using a Two-fragment PCR Approach. Bio-protocol 10 (2020) e3484

Sarott R, Westphal M, Pfaff P, Korn C, Sykes D, Thais G et al. Highly Specific, Fluorescent Cannabinoid Type 2 Receptor Probes Enable Applications in Microscopy, Flow Cytometry and FRET-based Binding Assays. ChemRxiv Preprint (2019)

Thais G, Brennecke B, Atz K, Korn C, Sykes D, Sarott R et al. Drug Derived Fluorescent Probes for the Specific Visualization of Cannabinoid Type 2 Receptor - A Toolbox Approach. ChemRxiv Preprint (2019)

Heydenreich FM*, Miljus T*, Benoit R, Jaussi R, Milic D, Veprintsev DB. High-throughput mutagenesis using a two-fragment PCR approach. Scientific Reports 7 (2017) 6787

Venkatakrishnan AJ, Deupi X, Lebon G, Heydenreich FM, Flock T, Miljus T, Balaji S, Bouvier M, Veprintsev DB, Tate CG, Schertler GFX, Babu MM. Diverse activation pathways in class A GPCRs converge near the G protein-coupling region. Nature 536 (2016) 484-487

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