Smith J, Read ML, Hoffman J, Brown R, Bradshaw B, Campbell C, Cole T, Navas JD, Eatock F, Gundara JS, Lian E, Mcmullan D, Morgan NV, Mulligan L, Morrison PJ, Robledo M, Simpson MA, Smith VE, Stewart S, Trembath RC, Sidhu S, Togneri FS, Wake NC, Wallis Y, Watkinson JC, Maher ER, McCabe CJ, Woodward ER. Germline ESR2 mutation predisposes to medullary thyroid carcinoma and causes up-regulation of RET expression. Human Molecular Genetics. 2016 Mar 3. pii: ddw057. [Epub ahead of print]
Read ML, Seed RI, Kwan PP, Sharma N, Smith VE, Watkins RJ, Stratford AL, Kim DS, Ward S, Boelaert K, Franklyn JA, Turnell AS, McCabe CJ. The Proto-oncogene PBF Binds p53 and is Associated with Prognostic Features in Colorectal Cancer.
Molecular Carcinogenesis. 2016 Jan;55(1):15-26.
Garcia-Rendueles ME, Ricarte-Filho JC, Untch BR, Landa I, Knauf JA, Voza F, Smith VE, Ganly I, Taylor BS, Persaud Y, Oler G, Fang Y, Jhanwar SC, Viale A, Heguy A, Huberman KH, Giancotti F, Ghossein R, Fagin JA. NF2 Loss Promotes Oncogenic RAS-Induced Thyroid Cancers via YAP-Dependent Transactivation of RAS Proteins and Sensitizes Them to MEK Inhibition. Cancer Discovery. 2015 Nov;5(11):1178-93.
Okosieme O, Gilbert J, Abraham P, Boelaert K, Dayan C, Gurnell M, Leese G, McCabe C, Perros P, Smith V, Williams G, Vanderpump M. Management of primary hypothyroidism: statement by the British Thyroid Association Executive Committee. Clinical Endocrinology. 2015 May 23. [Epub ahead of print]
Read ML, Seed RI, Fong JC, Modasia B, Ryan GA, Watkins RJ, Gagliano T, Smith VE, Stratford AL, Kwan PK, Sharma N, Dixon OM, Watkinson JC, Boelaert K, Franklyn JA, Turnell AS, McCabe CJ. The PTTG1-Binding Factor (PBF/PTTG1IP) regulates p53 activity in thyroid cells. Endocrinology. 2014 Apr;155(4):1222-34
Lewy GD, Ryan GA, Read ML, Fong JCW, Seed RI, Sharma N, Smith VE, Kwan PP, Stewart SL, Warfield A, Melmed S, Eggo MC, Franklyn JA, McCabe CJ, Boelaert K. Regulation of Pituitary Tumor Transforming Gene (PTTG) expression and phosphorylation in thyroid cells. Endocrinology. 2013 Nov;154(11):4408-22.
Smith VE, Sharma N, Watkins RJ, Read ML, Ryan GA, Kwan PP, Martin A, Watkinson JC, Boelaert K, Franklyn JA, McCabe CJ. Manipulation of PBF/PTTG1IP phosphorylation status; a new therapeutic strategy for improving radioiodine uptake in thyroid and other tumors. Journal of Clinical Endocrinology & Metabolism.2013 Jul;98(7):2876-86
Featured in News and Views in Nature Reviews Endocrinology. 9, 508-509 (September 2013)Smith VE, Read ML, Turnell AS, Sharma N, Lewy GD, Fong JCW, Seed RI, Kwan P, Ryan G, Mehanna H, Chan SY, Darras VM, Boelaert K, Franklyn JA, McCabe CJ. PTTG-binding factor (PBF) is a novel regulator of the thyroid hormone transporter MCT8. Endocrinology. 2012 Jul;153(7):3526-36.
Research Highlight for Basic Research in Nature Reviews Endocrinology 8, 384 (July 2012)
Read ML, Lewy GD, Fong JC, Sharma N, Seed RI, Smith VE, Gentilin E, Warfield A, Eggo MC, Knauf JA, Leadbeater WE, Watkinson JC, Franklyn JA, Boelaert K, McCabe CJ. Proto-oncogene PBF/PTTG1IP regulates thyroid cell growth and represses radioiodide treatment. Cancer Research. 2011 Oct 1;71(19):6153-64.
Smith VE, Franklyn JA, McCabe CJ. Expression and function of the novel proto-oncogene PBF in thyroid cancer - a new target for augmenting radioiodine uptake. Journal of Endocrinology. 2011 Aug;210(2):157-63.
Smith VE, Franklyn JA, McCabe CJ. Pituitary tumor-transforming gene and its binding factor in endocrine cancer. Expert Reviews in Molecular Medicine. 2010 Dec 3;12:e38.
Watkins RJ, Read ML, Smith VE, Sharma N, Reynolds GM, Buckley L, Doig C, Campbell MJ, Lewy G, Eggo MC, Loubiere LS, Franklyn JA, Boelaert K, McCabe CJ. Pituitary tumor transforming gene binding factor: a new gene in breast cancer. Cancer Research, 2010 May 1;70(9):3739-49.
Smith VE, Read ML, Turnell AS, Watkins RJ, Watkinson JC, Lewy GD, Fong JC, James SR, Eggo MC, Boelaert K, Franklyn JA, McCabe CJ. A novel mechanism of sodium iodide symporter repression in differentiated thyroid cancer. Journal of Cell Science, 2009 Sep 15;122(Pt 18):3393-402.
James SR, Franklyn JA, Reaves BJ, Smith VE, Chan SY, Barrett TG, Kilby MD, McCabe CJ. Monocarboxylate transporter 8 in neuronal cell growth. Endocrinology. 2009 Apr;150(4):1961-9.
Smith VE*, Boelaert K*, Stratford AL, Kogai T, Tannahill LA, Watkinson JC, Eggo MC, Franklyn JA, McCabe CJ. *Joint First Author. PTTG and PBF repress the human sodium iodide symporter. Oncogene. 2007 Jun 28;26(30):4344-56.
Aulchenko YS, Pullen J, Kloosterman WP, Yazdanpanah M, Hofman A, Vaessen N, Snijders PJLM, Mackay I, Olavesen M, Sidhu B, Smith VE, Carey A, Berezikov E, Uittenlinden AG, Plasterk RHA, Oostra BA, van Duijn CM. LPIN2 is associated with type 2 diabetes, glucose metabolism and body composition. Diabetes. 2007 Dec;56(12):3020-6.
Kim DS, Franklyn JA, Smith VE, Stratford AL, Pemberton HN, Warfield A, Watkinson JC, Ishmail T, Wakelam MJ, McCabe CJ. Securin induces genetic instability in colorectal cancer by inhibiting double-stranded DNA repair activity. Carcinogenesis. 2007. 28(3):749-59
Treloar SA, Wicks J, Nyholt DR, Montgomery GW, Bahlo M, Smith V, Dawson G, Mackay IJ, Weeks DE, Bennett ST, Carey A, Ewen-White KR, Duffy DL, O'connor DT, Barlow DH, Martin NG, Kennedy SH. Genomewide linkage study in 1,176 affected sister pair families identifies a significant susceptibility locus for endometriosis on chromosome 10q26. American Journal of Human Genetics. 2005 Sep;77(3):365-76
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