Recent publications
Article
Elsworthy, R, Crowe, J, King, M, Dunleavy, C, Fisher, E, Ludlam, A, Parri, R, Hill, EJ & Aldred, S 2022, 'The effect of citalopram treatment on amyloid-β precursor protein processing and oxidative stress in human hNSC-derived neurons', Translational Psychiatry, vol. 12, no. 1, 285. https://doi.org/10.1038/s41398-022-02050-5
Balter, LJT, Raymond, JE, Aldred, S, Higgs, S & Bosch, JA 2021, 'Age, BMI, and inflammation: associations with emotion recognition', Physiology and Behavior, vol. 232, 113324. https://doi.org/10.1016/j.physbeh.2021.113324
Elsworthy, R, King, M, Grainger, A, Fisher, E, Crowe, J, Alqattan, S, Ludlam, A, Hill, EJ & Aldred, S 2021, 'Amyloid-β precursor protein processing and oxidative stress are altered in human iPSC-derived neuron and astrocyte co-cultures carrying presenillin-1 gene mutations following spontaneous differentiation', Molecular and Cellular Neuroscience, vol. 114, 103631. https://doi.org/10.1016/j.mcn.2021.103631
Fisher, E, Wood, S, Upthegrove, R & Aldred, S 2020, 'Designing a feasible exercise intervention in first-episode psychosis: exercise quality, engagement and effect', Psychiatry Research, vol. 286, 112840. https://doi.org/10.1016/j.psychres.2020.112840
Fisher, E, Wood, S, Elsworthy, R, Upthegrove, R & Aldred, S 2020, 'Exercise as a protective mechanism against the negative effects of oxidative stress in first-episode psychosis: a biomarker led study.', Translational Psychiatry, vol. 10, no. 1, 254. https://doi.org/10.1038/s41398-020-00927-x
Kasim, NF, Veldhuijzen van Zanten, J & Aldred, S 2020, 'Tai Chi is an effective form of exercise to reduce markers of frailty in older age', Experimental gerontology, vol. 135, 110925. https://doi.org/10.1016/j.exger.2020.110925
Elsworthy, R & Aldred, S 2020, 'The effect of age and obesity on platelet amyloid precursor protein processing and plasma markers of oxidative stress and inflammation', Experimental gerontology, vol. 132, 110838. https://doi.org/10.1016/j.exger.2020.110838
Balter, L, Higgs, S, Aldred, S, Bosch, J & Raymond, J 2019, 'Inflammation Mediates Body Weight and Ageing Effects on Psychomotor Slowing', Scientific Reports, vol. 9, no. 1, 15727, pp. 1-13. https://doi.org/10.1038/s41598-019-52062-3
Balter, LJT, Raymond, JE, Aldred, S, Drayson, MT, Veldhuijzen van Zanten, JJCS, Higgs, S & Bosch, JA 2019, 'Loneliness in healthy young adults predicts inflammatory responsiveness to a mild immune challenge in vivo', Brain, Behavior, and Immunity, vol. 82, pp. 298-301. https://doi.org/10.1016/j.bbi.2019.08.196
Chapter
Elsworthy, R & Aldred, S 2022, Ageing, neurodegeneration and Alzheimer’s disease: the underlying role of oxidative distress. in J Cobley & G Davison (eds), Oxidative Eustress in Exercise Physiology. 1st edn, Oxidative Stress and Disease, CRC Press, pp. 193-207. https://doi.org/10.1201/9781003051619-16
Review article
Elsworthy, R, Dunleavy, C, Whitham, M & Aldred, S 2022, 'Exercise for the prevention of Alzheimer's disease: multiple pathways to promote non-amyloidogenic AβPP processing', Aging and Health Research, vol. 2, no. 3, 100093. https://doi.org/10.1016/j.ahr.2022.100093
Dunleavy, C, Elsworthy, RJ, Upthegrove, R, Wood, SJ & Aldred, S 2022, 'Inflammation in first-episode psychosis: The contribution of inflammatory biomarkers to the emergence of negative symptoms, a systematic review and meta-analysis', Acta Psychiatrica Scandinavica, vol. 146, no. 1, pp. 6-20. https://doi.org/10.1111/acps.13416
Elsworthy, R, Hill, EJ, Dunleavy, C & Aldred, S 2022, 'The role of ADAM10 in astrocytes: implications for Alzheimer’s disease', Frontiers in Aging Neuroscience, vol. 14, 1056507. https://doi.org/10.3389/fnagi.2022.1056507
Elsworthy, RJ, Hill, EJ, Dunleavy, C & Aldred, S 2022, 'The role of ADAM10 in astrocytes: Implications for Alzheimer's disease', Frontiers in Aging Neuroscience, vol. 14, 1056507. https://doi.org/10.3389/fnagi.2022.1056507
Elsworthy, R & Aldred, S 2019, 'Depression in Alzheimer's disease: an alternative role for selective serotonin reuptake inhibitors?', Journal of Alzheimer's Disease, vol. 69, no. 3, pp. 651-661. https://doi.org/10.3233/JAD-180780
View all publications in research portal