The Centre of Membrane Proteins and Receptors (COMPARE) is a unique collaboration between the Universities of Birmingham and Nottingham that formally started in August 2016 with a combined £10m investment over five years.
The Centre brings together world-leading experts across the two institutions in the study of G-protein-coupled receptors (GPCRs) and tyrosine kinase-linked receptors (TKRs) to develop new approaches to study these important cell surface proteins in health and disease.
Our cutting-edge development in powerful imaging techniques enables researchers to visualise what happens when a drug binds to a cell surface receptor or protein in real-time and thereby identify new mechanisms of therapeutic intervention.
COMPARE COVID-19 Facility Access
Find out more at the COMPARE website
COMPARE is a single institute across two universities which aims to achieve new insights into membrane proteins and drug development using cutting-edge technologies and through collaboration and career development. The cross-university collaboration, underpinned by infrastructure and cutting-edge technology, creates a critical mass of specialists with the breadth of knowledge and know-how for the study of GPCRs and TKRs.
COMPARE is positioned to produce significant research impacts in terms of publications, grant funding, recruitment and approaches to drug discovery.
Team Science is a fundamental part of COMPARE, enabling a collaborative approach to developing the next generation of internationally recognised research stars.
The aim is to develop a state-of-the-art infrastructure in imaging and complementary technology to provide an environment that will attract leading research scientists and achieve international recognition for COMPARE. As part of this, we will form alliances with other centres of excellence in academia and with industrial partners.
COMPARE has a formal collaboration with the Centre for Research in Energy and Materials (CNPEM), Campinas, Brazil. This collaboration enables COMPARE to access very specialist equipment dedicated to the study of membrane proteins, as well as providing access to a library of natural products that is only available in Brazil. The specialist equipment includes one of the first fourth-generation synchrotron light sources in the world (Sirius) and two cyro-electron microscopes.
Our technologies page details all microscopes and capabilities.
The diagram below shows the equipment that is available to researchers in the Universities of Birmingham and Nottingham, and to BHF-funded cardiovascular researchers across the UK.
Please contact firstname.lastname@example.org for further information.
COMPARE Bioimage Competition 2021
Are you a bioimaging enthusiast? Does your research involve light microscopy and are you sitting on some great images you can’t wait to show off?
If so, COMPARE are delighted to invite you to participate in our new Bioimage Competition!
We want to celebrate the beauty of your images and reward you for it: the 3 best entries will receive Amazon vouchers (£75, £50 and £25 for 1st, 2nd and 3rd place respectively) and 10 hours free imaging on your choice of COMPARE’s imaging systems in Birmingham.
There are no restrictions on research theme or type of image, you can submit raw, processed or analysed images or movies originating from any light microscopy system.
For your chance of winning all you need to do is choose your favourites (maximum of 3) and submit them to email@example.com with a brief description of your images.
The competition is now open and we will be accepting entries until 11th December.
Images will be assessed by a panel of imaging experts and winners will be announced on our website on the 18th
Dr Deidre Kavanagh
COMPARE Microscopy Officer (March 2017 - May 2021)
Now moved to the University of Oxford as a Facility Manager of MICRON
COMPARE is a Research Centre that has been initially funded for five years and research is ongoing. See our latest news page for updates.
All major COMPARE publications are listed on the web page.