Real-time Electrolytic Oxygen Sensing
It is currently impossible to monitor O2 metabolism down to a single cell. Current oxygen demand measurements systems can lack sensitivity and are not biocompatible. Some are expensive and do not operate in real time. Our solution; A biocompatible oxygen demand assay (BOAD) utilising the unique behaviour of ferrocene carboxylic acid (FcA).
A new production method for boron carbide
Conventional processing of boron carbide powders involves the melting of boron oxide in an electric arc furnace with a graphite electrode at temperature in excess of 2500C. The interaction between the molten boron oxide and the carbon leads to the formation of boron carbide in a large solid ingot. This ingot has then to be ground down to powders with size below 10 microns. As boron carbide is the third hardest material in the world grinding is difficult. Our solution; A low temperature synthesis route which offers the potential to reduce energy requirements and labour costs.
The speed of mechanical shutters and modulators currently used in devices such as infra-red cameras is limited, these devices can also be bulky and noisy. Electro-optical modulation is an attractive alternative as it simplifies operation, provides significantly improved speed, shrinks dimensions and is silent.
Visual Meal Creator
The much publicised obesity epidemic continues to worsen in economically developed countries. There has been an increased interest in possible acute and long term weight management intervention strategies. The investigation of appetite regulation has been a popular avenue for those addressing the energy balance equation. Various methods have been employed to measure appetite e.g. accurate weighing of food consumed and food diaries. No one method is considered completely accurate. Our solution; The Visual Meal Creator (VIMEC) enables users to create a meal they would wish to consume using photographic images of food items in an extensive menu. Each selected item is placed on a dinner plate and the portion size selected. The program then automatically calculates the nutrient composition of the meal
Removal of rare earth magnets during repairs
Rare earth magnets are used in a wide range of industrial devices. Many of these devices, especial those employed in large scale applications need to be repaired or maintained and the rare earth magnet replaced. This is currently difficult and time consuming. Our new method overcomes these problems by using hydrogen decrepitation.
Simple 3D Surface Capture
The digitisation of 3d objects is an important tool used in a wide range of applications, including archaeology, the generation of CAD models from real objects, object reproduction using 3d printing, industrial quality control, biometrics, computer games and many others. The best quality systems use a laser beam to scan across an object, and measurements of the reflection of the beam allow the profile of the surface of the object to be computed. Current laser-based systems are costly and can be time-consuming to set up and use. These systems also require either multiple cameras or a rotating stage to fully profile the object. Our solution; A system which can be constructed from a small number of off the shelf components, namely a camera, beam projectors and mirrors. The system uses the projectors to project a number of carefully chosen light patterns onto the object. For each pattern, the camera acquires an image of the surface of the object. Multiple projectors and mirrors can be used to achieve all-round scanning by imaging the object from multiple viewpoints at the same time.
Quantification of therapeutic antibodies with R10Z8E9
R10Z8E9 is a murine monoclonal antibody for quantification of therapeutic antibodies in non human primate trials.
Ruthenium nano-particles for tissue, cell and materials imaging
Ruthenium nano-particles are attractive as luminescent probes. However it is difficult to form noble metal nano-particles. Our new method of bonding probes overcomes these problems.
Self-structuring nutritional products for controlled energy release
Liquid and soft-food nutritional formulations are highly palatable to consumers. However, their rapid emptying from the stomach and absorption can result in large fluctuations in blood glucose levels and limited satiating power. Such effects are detrimental to cognitive performance, physical performance and potentially long-term health. The consumption of liquid or soft foods that restructure in the stomach into gels offers one way slow down energy release from nutritional products and provide sustained feelings of fullness for consumers. To date, lack of effective technologies has limited progress in this exciting area of self-structuring nutritional products. Our solution; Gellan gum formulations which transform liquid and soft-food formulations into nutritional products that self-structure in the acidic environment of the stomach.
Long-lasting antibacterial stainless steel surfaces
A novel plasma surface alloying technique to harden stainless steel surfaces by co-alloying with N and/or C to form a hard, wearing resistant phase and at the same time introduce bacteria-killing agents, such as Ag or Cu, into a stainless steel surface.
A compact laser interferometric measuring device
Robotic hands are typically designed and made to perform a limited number of actions which have either been learnt or for which the hand is specifically designed. Current hands have a very limited ability to learn a grasp for a novel object which has not been encountered before; Our solution; A robotic hand which from one learned example can determine the optimal spatial relationship between each part of the hand and the surface contours of the object to maximize the likelihood of a grasp being effective.
Scanning probe energy loss spectroscopy
A novel technique developed and patented by the University of Birmingham combines the imaging capabilities of scanning tunnelling microscopy (STM) with the spectral information provided by electron energy loss spectroscopy (EELS) in reflection mode.
PRH/HHEX as a Novel Marker for Tumour Metastasis
PRH/HHEX has been shown to be a novel biomarker that allows differentiation between benign and metastatic breast and prostate tumours employing a novel antibody for PRH/HHEX (Proline rich homeodomain human haematopoetically expressed).
For further information - Datasheet from our collaborators at University of Bristol