Clinical Immunology Service

The Clinical Immunology Service (CIS), in the Institute of Immunology and Immunotherapy, provides a comprehensive range of laboratory services. In particular the CIS is a major testing centre for multiple myeloma, leukaemia/lymphoma, immunodeficiency, autoimmunity, renal and rheumatic diseases and allergy. The CIS laboratory liaises closely with other local laboratories, particularly histopathology, genetics and haematology.


We offer a range tests to facilitate the diagnosis of autoimmune and neuroimmunological disease, blood cancers, primary and secondary immunodeficiency, infections and allergy. This section of our website also contains our Laboratory Handbook, describing our range of tests and their interpretation.

Educational Content

Pictures of immunofluorescence, flow cytometry profiles and cytology for blood cancers, flow cytometry for immune deficiency, electrophoresis and paraprotein analysis and other exciting content, relevant to FRCPath, STP and HSTP examinations.

The Clinical Immunology Service is playing a pivotal role in our COVID-19 research.

Antibodies are formed as part of the normal immune response following natural infection by SARS-CoV-2 virus or following vaccination.

We offer a range of antibody testing against different components of the SARS-CoV-2 virus, and can provide guidance on the correct test to use depending on the intended clinical application, for example seroprevalence studies, determining response to vaccination and differentiating that from response to natural infection.

We are also developing quantitative tests that will help determine to what extent and duration an individual is protected from re-infection. Our antibody tests can be run from standard venous blood draws or using self-sampled dried blood spots.

Two hands in purple Latex gloves working with a tray of samples in a lab

Read the QUEST article SARS-CoV-2 Antibody ELISA Test FAQ's for participants on COCO and PREVENT studies See more COVID-19 Research