NMDAR antibody is associated with treatable limbic encephalitis and its target is the NMDA receptor which comprises four NR units, with each of the subunit has a molecular size of 100 kDa and together they form an ion channel/receptor. NMDAR antibody binds to the neuropils in the molecular layer of the hippocampus as well as the granular layer of the cerebellum
MDAR antibodies can also be determined using commercially available NR1 transfected cells.
Tumours: Ovarian teratoma (56%, young women).
Syndrome: Limbic encephalitis