This module will provide an in-depth understanding of cutting-edge technologies currently used in both basic science laboratories and clinical diagnostic laboratories for translational genetic, epigenetic and transcriptomic research. The module will cover both classical techniques such as Sanger sequencing and new technologies including semi-conductor-based sequencing (as observed in the Ion Torrent). It will illustrate how the understanding of genomics provides insights into cancer diagnosis, stratification and treatment. It will evaluate the latest information on current drug developments and stratified medicine initiatives, and how these research themes are being translated in the clinic.
20 Masters level credits
Module attendance required
Module taken over 2 weeks.
18/10/21 - 29/10/21
Assessment of this module comprises two components:
Essay - 3000 words (60% of overall mark)
Exam - 8 short answer questions (40% of overall mark)
Academics involved in the delivery of this module
The leads of this module are Dr Maarten Hoogenkamp and Dr Marco Saponaro, with lecturers drawn from both the University of Birmingham and the National Health Service in order to deliver a module that teaches
both the basics of the technologies and their clinical relevance. Lectures will also be provided by bioinformaticians within the University, who will illustrate how dataset analyses can unpick the relevant biology of a disease.