Genomics and genome-based therapeutics

Module overview

This module will provide an in-depth understanding of cutting-edge technologies currently used in both basic science laboratories and clinical diagnostic laboratories for translational genetic, epigenetic and transcriptomic research. The module will cover both classical techniques such as Sanger sequencing and new technologies including semi-conductor-based sequencing (as observed in the Ion Torrent). It will illustrate how the understanding of genomics provides insights into cancer diagnosis, stratification and treatment. It will evaluate the latest information on current drug developments and stratified medicine initiatives, and how these research themes are being translated in the clinic.

Credits

20 Masters level credits

Module attendance required

Module taken over 2 weeks.

Module dates

21 October – 1 November 2019

Assesment

Summatively assessed with a 10 short answer question (SAQ) exam (2h) (60%) and with a 3000 word essay (40%).

Academics involved in the delivery of this module 

Professor Jo Morris and Dr Clare Davies, with lecturers drawn from both the University of Birmingham and the National Health Service in order to deliver a module that teaches
both the basics of the technologies and their clinical relevance. Lectures will also be provided by bioinformaticians within the University, who will illustrate how dataset analyses can unpick the relevant biology of a disease.