Dr Alessio Alexiadis PhD

Dr Alessio Alexiadis

School of Chemical Engineering
Senior Lecturer

Contact details

University of Birmingham
B15 2TT

Dr Alexiadis is Lecturer in Chemical Engineering at the University of Birmingham. He has published over 70 research papers in international journals, the majority of which as first or only author. His career has a strong international dimension. He has worked in 11 institutions, 8 countries and 4 continents and still collaborates with many of his previous colleagues and institutions.


  •  PhD in Chemical Engineering, 2002
  • BSc in Chemical Engineering, 1998


Dr. Alessio Alexiadis is currently working as Senior Lecturer at the University of Birmingham on hybrid modelling and computer simulations. He accomplished his Ph.D. in 2001 at the Politecnico di Torino (Italy). Since then, he has worked at the École Nationale Supérieure des Mines de Paris (2001−2003), Max-Planck-Institut für Kohlenforschung (2003−2004), University of New South Wales (2004−2006), University of Cyprus (2006-2008), Washington University in St. Louis (2008-2010), KTH - Royal Institute of Technology (2010-2011) and University of Warwick (2012-2013).

He has been PI or co-I in various research projects supported by research councils and other funding bodies in UK, Australia, USA and EU. In 2008 he was awarded of the Outgoing International Fellowship by the European Commission within the Marie Curie programme.

His current research mainly focuses on Discrete Multiphysics and Deep Multiphysics. Past research activities include photocatalysis, computational fluid dynamics, bubbly flows, multiphase reactors, polymer dynamics, membrane science, global warming modelling, electrochemistry, micro- and nano-fluidics, and both classical and ab initio molecular simulations.


  • MCT – Modelling Concepts and Tools


Current research research grants/funding

  • Advanced in-vitro and in-silico models to predict and prevent deep venous thrombosis – NC/S001360/1 (co-I) funded by NC3Rs
  • Martian Geopolymers: from building materials to water-recycling membranes − RPG-2018-204 (PI) funded by the Leverhulme Trust
  • A computing framework for Discrete Multiphysics − EP/S019227/1 (PI) funded by EPSRC
  • Discrete Multi-physics modeling of hydrate blockage in pipelines − 841814-HYDROBLOCK (PI) funded by European Commission
  • DMHS computer simulations of cavitation-induced pressure waves and erosion of nearby solid surfaces − N0014-16-R-BA01, NICOP (PI) funded by US Office of Naval Research
  • A holistic framework for hybrid modelling of solid-liquid flows − EP/N033698/1 (co-I) funded by EPSRC
  • Investigating powder catalyst manufacturing processes to product quality and performances (PI) Eng. D. funded by EPSRC Centre for Doctoral Training in Formulation Engineering
  • Experimental and computational investigation of physical predictors of deep venous thrombosis (co-I) Ph.D. funded by EPSRC Centre for Physical Sciences for Health
  • Discrete computational modelling of twin screw granulation − EP/M02959X/1 (co-I) funded by EPSRC

Past research grants/funding

  • Feedback destabilising control of electrosmotic flow for reducing fouling and enhancing productivity of membrane systems − DP110101643 (co-I) funded by Australian Research Council
  • Next generation turbulent CFD modelling for the electrochemical process − CN 40877 (PI) funded by European Commission

Teaching grants/funding

  • Educational Enhancement Project: Engineering of the 21st century, from the classroom to the real world − CSLP009 funded by CLAD (University of Birmingham)

Other grants/funding

  • Computational and experimental analyses of factors promoting thrombosis in veins and heart (co-I) funded by EPSRC Institutional Sponsorship Fund (University of Birmingham)


  • Alexiadis A. (2019) From Discrete Multiphysics to Deep Multiphysics: a case study concerning the design of continuous microfluidic devices for cell separation Journal of Applied Sciences 9:5369
  • Alexiadis A. (2019) Deep Multiphysics: Coupling Discrete Multiphysics with Machine Learning to attain self-learning in-silico models replicating human physiology Artificial Intelligence in Medicine 98:27-34
  • Anagnostopoulos A., Alexiadis A., Ding Y. (2019) Molecular Dynamics Simulation of Solar Salt (NaNO3-KNO3) mixtures Solar Energy Materials and Solar Cells 200:109897
  • Rahmat A., Barigou M., Alexiadis A. (2019) Nucleated Cells under Shear: a Discrete Multiphysics Study Physics of Fluids 31:051903
  • Sahputra I., Alexiadis A., Adams M. (2019) Effects of Moisture on the Mechanical Properties of Microcrystalline Cellulose and the Mobility of the Water Molecules as Studied by the Hybrid Molecular Mechanics-Molecular Dynamics Simulation Method Journal of Polymer Science, Part B: Polymer Physics 57:454–464
  • Sahputra I., Alexiadis A., Adams M. (2018) Temperature dependence of the Young’s Modulus of Polymers calculated using a Hybrid Molecular-Mechanics/Molecular-Dynamics Method Journal of Physics: Condensed Matter 30:355901
  • Ariane M., Kassinos S., Velaga S., Alexiadis A. (2018) Discrete multi-physics simulations of diffusive and convective mass transfer in boundary layers containing motile cilia in lungs Computers in Biology and Medicine 95:34–42
  • Taylor L., Alberini F., Meyer M., Alexiadis A. (2018) Study of the rheological properties of water and Martian soil simulant mixtures for engineering applications on the red planet, Advances in Space Research 61:6 1490–1500
  • Ariane M., Wen W., Vigolo D., Brill A., Nash G. B., Barigou M., Alexiadis A. (2017) Modelling and simulation of flow and agglomeration in deep veins valves using Discrete Multi Physics. Computers in Biology and Medicine 89: 96–103
  • Alexiadis A., Alberini F., Meyer M. E. (2017) Geopolymers from lunar and Martian soil simulants, Advances in Space Research 59: 490–495.
  • Alexiadis A., Stamatopoulos K., Wen W., Bakalis S., Barigou M.,Simmons M. (2017) Using discrete multi-physics for detailed exploration of hydrodynamics in an in vitro colon system Computers in Biology and Medicine 81:188–198.
  • Geng Q., Lasfargues M., Alexiadis A., Yulong D. (2017) Simulation and Experimental Study of the Specific Heat Capacity of Molten Salt based Nanofluids Applied thermal engineering 111:25 1517–1522.
  • Alexiadis A., (2015) The Discrete Multi-Hybrid System for the simulation of solid-liquid flows PLoS ONE 10(5): e0124678
  • Alexiadis A., Lockerby D.A., Borg M.K. and Reese J.M. (2014), The atomistic-continuum hybrid taxonomy and the hybrid-hybrid approach, International Journal for Numerical Methods in Engineering 98: 534-546
  • Alexiadis A., Dudukovic M.P., Ramachandran P., Cornell A., Wanngård J. and Bokkers A. (2012), Transition to Pseudo-Turbulence in a Narrow Gas-Evolving Channel, Theoretical and Computational Fluid Dynamics, 26:551-564
  • Alexiadis A., Dudukovic M.P., Ramachandran P., Cornell A. (2012), On the stability of the flow in multichannel electrochemical systems, Journal of Applied Electrochemistry, 42:679-687
  • Alexiadis A., Dudukovic M.P., Ramachandran P., Cornell A., Wanngård J. and Bokkers A. (2011), On the electrode boundary conditions in the simulation of two phase flow in electrochemical cells, International Journal of Hydrogen Energy, 36:8557-8559
  • Alexiadis A. and Kassinos S. (2010), On the use of the BLYP functional for the DFT calculation of graphite-hydrogen systems, Journal of Nuclear Materials, 396:307-308
  • Yee K. W. K., Alexiadis A., Bao J. and Wiley D. E. (2009), Effects of recycle ratios on process dynamics and operability of a whey ultra-filtration stage, Desalination, 236:216-223
  • Alexiadis A. and Kassinos S. (2008), Molecular Dynamics of Water in Carbon Nanotubes, Chemical Reviews, 108:5014–5034
  • Alexiadis A. and Kassinos S.  (2008), Molecular dynamic simulations of carbon nanotubes in CO2 atmosphere, Chemical Physics Letters, 460:512-516
  • Alexiadis A., Gardin P. and Domgin J. F. (2007), Probabilistic Approach for Break-up and Coalescence in Bubbly-Flow and Coupling with CFD Codes, Applied Mathematical Modelling, 31:2051-2061
  • Alexiadis A. (2007), Global warming and human activity: A model for studying the potential instability of the carbon dioxide/temperature feedback mechanism, Ecological Modelling, 203:243-256
  • Alexiadis A. (2006), 2-D Radiation field in photocatalytic channels of square, rectangular, equilateral triangular and isosceles triangular sections, Chemical Engineering Science, 61:516-525
  • Alexiadis A., Bao J., Fletcher D. F., Wiley D. E. and Clements D. J. (2006), Dynamic Response of a Reverse Osmosis High-Pressure Membrane to Time Dependent Disturbances, Desalination, 191:397-403
  • Alexiadis A., Bao J., Fletcher D. F., Wiley D. E. and Clements D. J. (2005), Analysis of the Dynamic Response of a Reverse Osmosis Membrane to Time Dependent Transmembrane Pressure Variation, Industrial & Engineering Chemistry Research, 20:7823-7834
  • Alexiadis A. and Mazzarino I. (2005), Design Guidelines for Fixed Bed Photocatalytic Reactors, Chemical Engineering and Processing, 44:453-459
  • Alexiadis A., Gardin P. and Domgin J. F. (2004), Spot turbulence, Break-up and Coalescence of Bubbles released from a Porous Plug Injector into a Gas-Stirred Ladle, Metallurgical and Materials Transaction B, 35B:949-956
  • Alexiadis A., Andes C., Ferrari D., Korber K., Hauschild K., Bochmann M. and Fink G. (2004), Mathematical Modelling of Homo-Polymerization on Supported Metallocene Catalyst, Macromolecular Materials and Engineering, 289:457-466
  • Alexiadis A., Vanni M. and Gardin P. (2004), Extension of the Method of Moments for Population Balances Involving Fractional Moments and Application to a Typical Agglomeration Case, Journal of Colloid and Interface Science, 276:106-112
  • Raupp G. B., Alexiadis A., Moazzem Hossain M. M. and Changrani R. (2001), First-principles modeling, scaling laws and design of structured photocatalytic oxidation reactors for air purification, Catalysis Today, 69:41-49

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