Mr Sivesh Kathir Kamarajah BMedSci, MBChB, MRCS

Mr Sivesh Kathir Kamarajah

Institute of Applied Health Research
NIHR Doctoral Fellow

Contact details

Institute of Applied Health Research
University of Birmingham
B15 2TT

Sivesh is a NIHR Doctoral Fellow and General Surgery Registrar in the West Midlands. He is undertaking a mixed methods PhD on developing and testing complex interventions for multimorbidity in surgical patients. His PhD is based on utilising principles of the NIHR / MRC Complex Intervention framework and includes methodologies such as data science and implementation science.

ORCiD iD: 0000-0002-2748-0011

Google Scholar profile 

ResearchGate profile 

PubMed profile


Diploma of Membership of the Royal College of Surgeons (MRCS), RCS England 2021

MBChB in Medicine, University of Birmingham, 2018

BMedSci in Liver Immunology, University of Birmingham, 2016


Sivesh Kamarajah is from Malaysia and read medicine at University of Birmingham. He completed the academic foundation programme in Newcastle upon Tyne Hospitals NHS Trust & University of Newcastle from 2018 - 2020.

Sivesh then moved back to University of Birmingham as a NIHR Academic Clinical Fellow (2020 - 2023) as a General Surgery Trainee. Following a competitive application process, he was successfully awarded the NIHR Doctoral Fellowship to undertake a clinical PhD on “Learning to develop randomised trials for people with multiple long-term health conditions undergoing major surgery”.

Sivesh has delivered national and international cohort studies in surgery and perioperative care. He was Chief Investigator of an international cohort study assessing postoperative cardiac complications after major abdominal surgery (CASCADE), including >24,000 patients across 446 hospitals from 29 countries in Europe. He is currently co-leading the GECKO GlobalSurg-4 cohort study including >53,000 patients from >1,200 hospital from 108 countries.


Intercalated BSc project supervisor (Anatomy)

BMedSci project supervisor

Other activities

Current Membership of Committees:

  • Senior Lead, Student Audit & Research in Surgery (STARSurg) collaborative
  • Audit & Research Lead, Roux Group

Past Membership of Committees:

  • SRS Academic Representative (2020 - 2022)


STARSurg Collaborative; EuroSurg Collaborative, Kamarajah SK. Impact of postoperative cardiovascular complications on 30-day mortality after major abdominal surgery: an international prospective cohort study. Anaesthesia. 2024 Feb 2. doi: 10.1111/anae.16220.

NIHR Global Health Unit on Global Surgery. Evaluation of a quality improvement intervention to reduce anastomotic leak following right colectomy (EAGLE): pragmatic, batched stepped-wedge, cluster-randomized trial in 64 countries. British Journal of Surgery. Jan 3;111(1). doi: 10.1093/bjs/znad370.

Lof S, Claassen L, Hannink G, Al-Sarireh B, Björnsson B, Boggi U, Burdio F, Butturini G, Capretti G, Casadei R, Dokmak S, Edwin B, Esposito A, Fabre JM, Ferrari G, Fretland AA, Ftériche FS, Fusai GK, Giardino A, Groot Koerkamp B, D'Hondt M, Jah A, Kamarajah SK, Kauffmann EF, Keck T, van Laarhoven S, Manzoni A, Marino MV, Marudanayagam R, Molenaar IQ, Pessaux P, Rosso E, Salvia R, Soonawalla Z, Souche R, White S, van Workum F, Zerbi A, Rosman C, Stommel MWJ, Abu Hilal M, Besselink MG Learning Curves of Minimally Invasive Distal Pancreatectomy in Experienced Pancreatic Centers. JAMA Surg. 2023 Sep 1;158(9):927-933. doi: 10.1001/jamasurg.2023.2279.

GreenSurg Collaborative, 2023, 'Elective surgical services need to start planning for summer pressures', British Journal of Surgery, vol. 110, no. 4, pp. 508-510.

Moore JL, Green M, Santaolalla A, Deere H, Evans RPT, Elshafie M, Lavery A, McManus DT, McGuigan A, Douglas R, Horne J, Walker R, Mir H, Terlizzo M, Kamarajah SK, Van Hemelrijck M, Maisey N, Sita-Lumsden A, Ngan S, Kelly M, Baker CR, Kumar S, Lagergren J, Allum WH, Gossage JA, Griffiths EA, Grabsch HI, Turkington RC, Underwood TJ, Smyth EC, Fitzgerald RC, Cunningham D, Davies AR; ‘Pathologic Lymph Node Regression After Neoadjuvant Chemotherapy Predicts Recurrence and Survival in Esophageal Adenocarcinoma: A Multicenter Study in the United Kingdom.’J Clin Oncol. 2023 Oct 1;41(28):4522-4534. doi: 10.1200/JCO.23.00139. Epub 2023 Jul 27.  PMID: 37499209

Kamarajah SK, Markar SR, Low D, Phillips AW (2023). Prognostic implications of the extent of downstaging after neoadjuvant therapy for oesophageal adenocarcinoma and oesophageal squamous cell carcinoma. BJS Open. 7(3):zrad042. doi: 10.1093/bjsopen/zrad042. PMID: 37341158

Oesophago-Gastric Anastomotic Audit (OGAA) Collaborative, Kamarajah SK. Postoperative and Pathological Outcomes of CROSS and FLOT as Neoadjuvant Therapy for Esophageal and Junctional Adenocarcinoma: An International Cohort Study From the Oesophagogastric Anastomosis Audit (OGAA). Ann Surg. 2023 May 1;277(5):e1026-e1034. doi: 10.1097/SLA.0000000000005394.

National Institute of Health Research Unit on Global Surgery, Kamarajah SK (2022). Alcoholic chlorhexidine skin preparation or triclosan-coated sutures to reduce surgical site infection: a systematic review and meta-analysis of high-quality randomised controlled trials. Lancet Infect Dis. 2022 Aug;22(8):1242-1251. doi: 10.1016/S1473-3099(22)00133-5. Epub 2022 May 26.

STARSurg Collaborative and TASMAN Collaborative, Kamarajah SK. Evaluation of prognostic risk models for postoperative pulmonary complications in adult patients undergoing major abdominal surgery: a systematic review and international external validation cohort study. Lancet Digit Health. 2022 Jul;4(7):e520-e531. doi: 10.1016/S2589-7500(22)00069-3.

NIHR Global Health Research Unit on Global Surgery, COVIDSurg Collaborative, 2022, 'Elective surgery system strengthening: development, measurement, and validation of the surgical preparedness index across 1632 hospitals in 119 countries', The Lancet, vol. 400, no. 10363, pp. 1607-1617.

STARSurg Collaborative and TASMAN Collaborative 2022, 'Evaluation of prognostic risk models for postoperative pulmonary complications in adult patients undergoing major abdominal surgery: a systematic review and international external validation cohort study', The Lancet Digital Health, vol. 4, no. 7, pp. e520-e531.

STARSurg Collaborative 2022, 'Impact of postoperative acute kidney injury in patients undergoing major gastrointestinal surgery on 1-year survival and renal outcomes: a national multicentre cohort study', BJS Open, vol. 5, no. 6, zrab134.

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