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Whittle, R, Riley, RD, Archer, L, Collins, GS, Legha, A, Snell, KIE & Ensor, J 2026, 'A decomposition of Fisher’s information to inform sample size for developing or updating fair and precise clinical prediction models – part 3: continuous outcomes', Diagnostic and Prognostic Research, vol. 10, no. 1, 11. https://doi.org/10.1186/s41512-026-00228-9
Riley, RD, Collins, GS, Whittle, R, Archer, L, Snell, KIE, Dhiman, P, Kirton, L, Legha, A, Liu, X, Denniston, AK, Harrell, FE, Wynants, L, Martin, GP & Ensor, J 2025, 'A decomposition of Fisher's information to inform sample size for developing or updating fair and precise clinical prediction models for individual risk-part 1: binary outcomes', Diagnostic and Prognostic Research, vol. 9, no. 1, 14. https://doi.org/10.1186/s41512-025-00193-9
Riley, RD, Collins, GS, Archer, L, Whittle, R, Legha, A, Kirton, L, Dhiman, P, Sadatsafavi, M, Adderley, NJ, Alderman, J, Martin, GP & Ensor, J 2025, 'A decomposition of Fisher’s information to inform sample size for developing or updating fair and precise clinical prediction models - Part 2: time-to-event outcomes', Diagnostic and Prognostic Research, vol. 9, no. 1, 33. https://doi.org/10.1186/s41512-025-00204-9
Whittle, R, Ensor, J, Archer, L, Collins, GS, Dhiman, P, Denniston, A, Alderman, J, Legha, A, van Smeden, M, Moons, KG, Cazier, J-B, Riley, RD & Snell, KIE 2025, 'Extended sample size calculations for evaluation of prediction models using a threshold for classification', BMC Medical Research Methodology, vol. 25, no. 1, 170. https://doi.org/10.1186/s12874-025-02592-4
Legha, A, Ensor, J, Whittle, R, Archer, L, Van Calster, B, Christodoulou, E, Snell, KIE, Sadatsafavi, M, Collins, GS & Riley, R 2025, 'Sequential sample size calculations and learning curves safeguard the robust development of a clinical prediction model for individuals', Journal of Clinical Epidemiology. https://doi.org/10.1016/j.jclinepi.2025.112117
Martin, J, Scandrett, K, Easter, C, Whittle, R, Legha, A, Hillier, B, Thompson, J & Archer, L 2025, 'The Role of Generative AI in Data Analysis Assessments', Education in Practice, vol. 6, no. 1, pp. 107-116. <https://education-in-practice.co.uk/education-in-practice-issue-6-spring-2025/>
Legha, A, Bailey, J, Welsh, VK, Jordan, KP, Holdsworth, C & Wynne-Jones, G 2025, 'Trajectories of work absence in England due to a Musculoskeletal or Mental Health condition: An electronic health record cohort study', Journal of Occupational Rehabilitation. https://doi.org/10.1007/s10926-025-10342-y
The STEER OA Patient Advisory Group & The OA Trial Bank Exercise Collaborative 2023, 'Moderators of the effect of therapeutic exercise for knee and/or hip osteoarthritis: a systematic review and individual participant data meta-analysis with the OA trial bank', The Lancet Rheumatology, vol. 5, no. 7, pp. e386-e400. https://doi.org/10.1016/S2665-9913(23)00122-4
Riley, RD, Legha, A, Jackson, D, Morris, TP, Ensor, J, Snell, KIE, White, IR & Burke, DL 2020, 'One-stage individual participant data meta-analysis models for continuous and binary outcomes: Comparison of treatment coding options and estimation methods', Statistics in Medicine, vol. 39, no. 19, pp. 2536-2555. https://doi.org/10.1002/sim.8555
Legha, A, Riley, RD, Ensor, J, Snell, KIE, Morris, TP & Burke, DL 2018, 'Individual participant data meta-analysis of continuous outcomes: A comparison of approaches for specifying and estimating one-stage models', Statistics in Medicine, vol. 37, no. 29, pp. 4404-4420. https://doi.org/10.1002/sim.7930, https://doi.org/10.1002/sim.v37.29
Preprint
Riley, RD, Collins, GS, Whittle, R, Archer, L, Snell, KIE, Dhiman, P, Kirton, L, Legha, A, Liu, X, Denniston, A, Harrell Jr, FE, Wynants, L, Martin, GP & Ensor, J 2025 'A decomposition of Fisher's information to inform sample size for developing fair and precise clinical prediction models -- part 1: binary outcomes' arXiv. https://doi.org/10.48550/arXiv.2407.09293
Riley, RD, Collins, GS, Archer, L, Whittle, R, Legha, A, Kirton, L, Dhiman, P, Sadatsafavi, M, Adderley, NJ, Alderman, J, Martin, GP & Ensor, J 2025 'A decomposition of Fisher's information to inform sample size for developing fair and precise clinical prediction models -- Part 2: time-to-event outcomes' arXiv. <https://arxiv.org/abs/2501.14482>
Whittle, R, Riley, RD, Archer, L, Collins, GS, Legha, A, Snell, KIE & Ensor, J 2025 'A decomposition of Fisher's information to inform sample size for developing or updating fair and precise clinical prediction models -- Part 3: continuous outcomes' arXiv. https://doi.org/10.48550/arXiv.2507.23548
Legha, A, Ensor, J, Whittle, R, Archer, L, Van Calster, B, Christodoulou, E, Snell, KIE, Sadatsafavi, M, Collins, GS & Riley, RD 2025 'Sequential sample size calculations and learning curves safeguard the robust development of a clinical prediction model for individuals' arXiv. https://doi.org/10.48550/arXiv.2509.15134
Whittle, R, Ensor, J, Archer, L, Collins, GS, Dhiman, P, Denniston, A, Alderman, J, Legha, A, van Smeden, M, Moons, KG, Cazier, J-B, Riley, RD & Snell, KIE 2024 'Extended sample size calculations for evaluation of prediction models using a threshold for classification' arXiv. https://doi.org/10.48550/arXiv.2406.19673
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