Recent publications
Article
Riley, RD, Collins, GS, Whittle, R, Archer, L, Snell, KIE, Dhiman, P, Kirton, L, Legha, A, Liu, X, Denniston, AK, Harrell, FE, Wynants, L, Martin, GP & Ensor, J 2025, 'A decomposition of Fisher's information to inform sample size for developing or updating fair and precise clinical prediction models for individual risk-part 1: binary outcomes', Diagnostic and Prognostic Research, vol. 9, no. 1, 14. https://doi.org/10.1186/s41512-025-00193-9
Riley, R, Collins, G, Archer, L, Whittle, R, Legha, A, Kirton, L, Dhiman, P, Sadatsafavi, M, Adderley, N, Alderman, J, Martin, GP & Ensor, J 2025, 'A decomposition of Fisher’s information to inform sample size for developing or updating fair and precise clinical prediction models - Part 2: time-to-event outcomes', Diagnostic and Prognostic Research.
Whittle, R, Ensor, J, Archer, L, Collins, GS, Dhiman, P, Denniston, A, Alderman, J, Legha, A, van Smeden, M, Moons, KG, Cazier, J-B, Riley, RD & Snell, KIE 2025, 'Extended sample size calculations for evaluation of prediction models using a threshold for classification', BMC Medical Research Methodology, vol. 25, no. 1, 170. https://doi.org/10.1186/s12874-025-02592-4
Martin, J, Scandrett, K, Easter, C, Whittle, R, Legha, A, Hillier, B, Thompson, J & Archer, L 2025, 'The Role of Generative AI in Data Analysis Assessments', Education in Practice, vol. 6, no. 1, pp. 107-116. <https://bham.sharepoint.com/sites/aseddev/Shared%20Documents/EiP%20Journal%20Vol%206.1/10_Martin_EIP_6.1%20Spring%202025.pdf?csf=1&web=1&e=zOUylv>
Legha, A, Bailey, J, Welsh, VK, Jordan, KP, Holdsworth, C & Wynne-Jones, G 2025, 'Trajectories of work absence in England due to a Musculoskeletal or Mental Health condition: An electronic health record cohort study', Journal of Occupational Rehabilitation. https://doi.org/10.1007/s10926-025-10342-y
The STEER OA Patient Advisory Group & The OA Trial Bank Exercise Collaborative 2023, 'Moderators of the effect of therapeutic exercise for knee and/or hip osteoarthritis: a systematic review and individual participant data meta-analysis with the OA trial bank', The Lancet Rheumatology, vol. 5, no. 7, pp. e386-e400. https://doi.org/10.1016/S2665-9913(23)00122-4
Riley, RD, Legha, A, Jackson, D, Morris, TP, Ensor, J, Snell, KIE, White, IR & Burke, DL 2020, 'One-stage individual participant data meta-analysis models for continuous and binary outcomes: Comparison of treatment coding options and estimation methods', Statistics in Medicine, vol. 39, no. 19, pp. 2536-2555. https://doi.org/10.1002/sim.8555
Legha, A, Riley, RD, Ensor, J, Snell, KIE, Morris, TP & Burke, DL 2018, 'Individual participant data meta-analysis of continuous outcomes: A comparison of approaches for specifying and estimating one-stage models', Statistics in Medicine, vol. 37, no. 29, pp. 4404-4420. https://doi.org/10.1002/sim.7930, https://doi.org/10.1002/sim.v37.29
Preprint
Riley, RD, Collins, GS, Whittle, R, Archer, L, Snell, KIE, Dhiman, P, Kirton, L, Legha, A, Liu, X, Denniston, A, Harrell Jr, FE, Wynants, L, Martin, GP & Ensor, J 2025 'A decomposition of Fisher's information to inform sample size for developing fair and precise clinical prediction models -- part 1: binary outcomes' arXiv. https://doi.org/10.48550/arXiv.2407.09293
Riley, RD, Collins, GS, Archer, L, Whittle, R, Legha, A, Kirton, L, Dhiman, P, Sadatsafavi, M, Adderley, NJ, Alderman, J, Martin, GP & Ensor, J 2025 'A decomposition of Fisher's information to inform sample size for developing fair and precise clinical prediction models -- Part 2: time-to-event outcomes' arXiv. <https://arxiv.org/abs/2501.14482>
Whittle, R, Riley, RD, Archer, L, Collins, GS, Legha, A, Snell, KIE & Ensor, J 2025 'A decomposition of Fisher's information to inform sample size for developing or updating fair and precise clinical prediction models -- Part 3: continuous outcomes' arXiv. https://doi.org/10.48550/arXiv.2507.2354
Legha, A, Ensor, J, Whittle, R, Archer, L, Van Calster, B, Christodoulou, E, Snell, KIE, Sadatsafavi, M, Collins, GS & Riley, RD 2025 'Sequential sample size calculations and learning curves safeguard the robust development of a clinical prediction model for individuals' arXiv. https://doi.org/10.48550/arXiv.2509.15134
Whittle, R, Ensor, J, Archer, L, Collins, GS, Dhiman, P, Denniston, A, Alderman, J, Legha, A, van Smeden, M, Moons, KG, Cazier, J-B, Riley, RD & Snell, KIE 2024 'Extended sample size calculations for evaluation of prediction models using a threshold for classification' arXiv. https://doi.org/10.48550/arXiv.2406.19673
Review article
Holden, MA, Burke, DL, Runhaar, J, Van der windt, D, Riley, RD, Dziedzic, K, Legha, A, Evans, AL, Abbott, JH, Baker, K, Brown, J, Bennell, KL, Bossen, D, Brosseau, L, Chaipinyo, K, Christensen, R, Cochrane, T, De rooij, M, Doherty, M, French, HP, Hickson, S, Hinman, RS, Hopman-Rock, M, Hurley, MV, Ingram, C, Knoop, J, Krauss, I, Mccarthy, C, Messier, SP, Patrick, DL, Sahin, N, Talbot, LA, Taylor, R, Teirlinck, CH, Van middelkoop, M, Walker, C & Foster, NE 2017, 'Subgrouping and TargetEd Exercise pRogrammes for knee and hip OsteoArthritis (STEER OA): a systematic review update and individual participant data meta-analysis protocol', BMJ open, vol. 7, no. 12, e018971. https://doi.org/10.1136/bmjopen-2017-018971
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