Recent publications
Article
Armitage, MN, Aishah, AZ, Huntley, C, Lasserson, D & Newnham, M 2022, 'A multicentre observational study of the prevalence, management, and outcomes of subsegmental pulmonary embolism', Journal of thrombosis and thrombolysis. https://doi.org/10.1007/s11239-022-02714-5
Hadinnapola , CM, Southwood, M, Hernandez-Sanchez, J, Bunclark, K, Newnham, M, Swietlik, EM, Cannon, J, Preston , SD, Sheares, K, Taboada, D, Screaton, N, Jenkins, DP, Morrell, NW, Toshner, M & Pepke-Zaba, J 2022, 'Angiopoietin 2 and hsCRP are associated with pulmonary haemodynamics and long-term mortality respectively in CTEPH - results from a prospective discovery and validation biomarker study', The Journal of Heart and Lung Transplantation. https://doi.org/10.1016/j.healun.2022.08.021
Loo, J, Spittle, D & Newnham, M 2021, 'COVID-19, immunothrombosis and venous thromboembolism: biological mechanisms', Thorax, vol. 76, no. 4, pp. 412-420. https://doi.org/10.1136/thoraxjnl-2020-216243
Bunclark, K, Newnham, M, Chiu, Y-D, Ruggiero, A, Villar, SS, Cannon, JE, Coghlan, G, Corris, PA, Howard, L, Jenkins, D, Johnson, M, Kiely, DG, Ng, C, Screaton, N, Sheares, K, Taboada, D, Tsui, S, Wort, SJ, Pepke-Zaba, J & Toshner, M 2020, 'A multicenter study of anticoagulation in operable chronic thromboembolic pulmonary hypertension', Journal of Thrombosis and Haemostasis, vol. 18, no. 1, pp. 114-122. https://doi.org/10.1111/jth.14649
Newnham, M, Bunclark, K, Abraham, N, Ali, S, Amaral-Almeida, L, Cannon, JE, Doughty, N, Ng, C, Ponnaberanam, A, Sheares, K, Speed, N, Taboada, D, Toshner, M, Tsui, S, Jenkins, DP & Pepke-Zaba, J 2020, 'CAMPHOR score: patient-reported outcomes are improved by pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension (CTEPH)', The European respiratory journal, vol. 56, no. 4, 1902096. https://doi.org/10.1183/13993003.02096-2019
Newnham, M, South, K, Bleda, M, Auger, W, Barberà, J, Bogaard, H, Bunclark, K, Cannon, J, Delcroix, M, Hadinnapola, C, Howard, L, Jenkins, D, Mayer, E, Ng, C, Rhodes, C, Screaton, N, Sheares, K, Simpson, M, Southwood, M, Su, L, Taboada, D, Traylor, M, Trembath, R, Villar, S, Wilkins, M, Wharton, J, Gräf, S, Pepe-Zaba, J, Laffan, M, Lane, D, Morrell, N & Toshner, M 2019, 'The ADAMTS13-VWF axis is dysregulated in chronic thromboembolic pulmonary hypertension.', European Respiratory Journal, vol. 53, no. 3, 1801805. https://doi.org/10.1183/13993003.01805-2018
Sofianopoulou, E, Kaptoge, S, Graf, S, Hadinnapola, C, Treacy, CM, Church, C, Coghlan, G, Gibbs, JSR, Haimel, M, Howard, L, Johnson, M, Kiely, DG, Lawrie, A, Lordan, J, MacKenzie Ross, RV, Martin, JM, Moledina, S, Newnham, M, Peacock, AJ, Price, L, Rhodes, CJ, Suntharalingam, J, Swietlik, EM, Toshner, MR, Wharton, J, Wilkins, MR, Wort, SJ, Pepke-Zaba, J, Condliffe, R, Corris, PA, Di Angelantonio, E, Provencher, S & Morrell, NW 2019, 'Traffic exposures, air pollution and outcomes in pulmonary arterial hypertension: a UK cohort study analysis', The European respiratory journal, vol. 53, no. 5, 1801429. https://doi.org/10.1183/13993003.01429-2018
Rhodes, CJ, K, B, Bleda, M, Haimel, M, Southgate, L, Germain, M, Pauciulo, MW, Hadinnapola, C, Aman, J, Girerd, B, Arora, A, Knight, J, Hanscombe, KB, Karnes, JH, Kaakinen, M, Gall, H, Ulrich, A, Harbaum, L, Cebola, I, Ferrer, J, Lutz, K, Swietlik, EM, Ahmad, F, Amouyel, P, Archer, SL, Argula, R, Austin, ED, Badesch, D, Bakshi, S, Barnett, C, Benza, R, Bhatt, N, Bogaard, HJ, Burger, CD, Chakinala, M, Church, C, Coghlan, JG, Condliffe, R, Corris, PA, Danesino, C, Debette, S, Elliot, CG, Elwing, J, Eyries, M, Fortin, T, Franke, A, Frantz, RP, Frost, A, Garcia, JGN, Ghio, S, Ghofrani, HA, Gibbs, JSR, Harley, J, He, H, Hill, NS, Hirsch, R, Houweling, AC, Howard, LS, Ivy, D, Kiely, DG, Klinger, J, Kovacs, G, Lahm, T, Laudes, M, Machado, RD, MacKenzie Ross, RV, Marsolo, K, Martin, LJ, Moledina, S, Montani, D, Nathan, SD, Newnham, M, Olschewski, A, Olschewski, H, Oudiz, RJ, Ouwehand, WH, Peacock, AJ, Pepke-Zaba, J, Rehman, Z, Robbins, I, Roden, DM, Rosenzweig, EB, Saydain, G, Scelsi, L, Schilz, R, Seeger, W, Shaffer, CM, Simms, RW, Simon, M, Sitbon, O, Suntharalingam, J, Tang, H, Tchourbanov, AY, Thenappen, T, Torres, F, Toshner, MR, Treacy, CM, Vonk Noordegraaf, A, Waisfisz, Q, Walsworth, AK, Walter, RE, Wharton, J, White, RJ, Wilt, J, Wort, SJ, Yung, D, Lawrie, A, Humbert, M, Humbert, M, Soubrier, F, Tregouet, DA, Prokopenko, I, Kittles, R, Graf, S, Nichols, WC, Trembath, RC, Desai, AA, Morrell, NW & Wilkins, MR 2018, 'Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis.', Lancet Respir Med, vol. 7, no. 3, pp. 227-238. https://doi.org/10.1016/S2213-2600(18)30409-0
Gräf, S, Haimel, M, Bleda, M, Hadinnapola, C, Southgate, L, Li, W, Hodgson, J, Liu, B, Salmon, RM, Southwood, M, Machado, RD, Martin, JM, Treacy, CM, Yates, K, Daugherty, LC, Shamardina, O, Whitehorn, D, Holden, S, Aldred, M, Bogaard, HJ, Church, C, Coghlan, G, Condliffe, R, Corris, PA, Danesino, C, Eyries, M, Gall, H, Ghio, S, Ghofrani, H, Gibbs, JSR, Girerd, B, Houweling, AC, Howard, L, Humbert, M, Kiely, DG, Kovacs, G, Mackenzie Ross, RV, Moledina, S, Montani, D, Newnham, M, Olschewski, A, Olschewski, H, Peacock, AJ, Pepke-zaba, J, Prokopenko, I, Rhodes, CJ, Scelsi, L, Seeger, W, Soubrier, F, Stein, DF, Suntharalingam, J, Swietlik, EM, Toshner, MR, Van Heel, DA, Vonk Noordegraaf, A, Waisfisz, Q, Wharton, J, Wort, SJ, Ouwehand, WH, Soranzo, N, Lawrie, A, Upton, PD, Wilkins, MR, Trembath, RC & Morrell, NW 2018, 'Identification of rare sequence variation underlying heritable pulmonary arterial hypertension', Nature Communications, vol. 9, no. 1, 1416. https://doi.org/10.1038/s41467-018-03672-4
Hadinnapola, C, Bleda, M, Haimel, M, Screaton, N, Swift, A, Dorfmuller, P, Preston, SD, Southwood, M, Hernandez-Sanchez, J, Martin, J, Treacy, C, Yates, K, Bogaard, H, Church, C, Coghlan, G, Condliffe, R, Corris, PA, Gibbs, S, Girerd, B, Holden, S, Humbert, M, Kiely, DG, Lawrie, A, Machado, R, MacKenzie Ross, R, Moledina, S, Newnham, M, Peacock, A, Pepke-Zaba, J, Rayner-Matthews, P, Shamardina, O, Soubrier, F, Southgate, L, Suntharalingam, J, Toshner, M, Trembath, R, Vonk Noordegraaf, A, Wilkins, MR, Wort, SJ, Wharton, J, Graf, S & Morrell, NW 2017, 'Phenotypic characterization of EIF2AK4 mutation carriers in a large cohort of patients diagnosed clinically with pulmonary arterial hypertension', Circulation, vol. 136, no. 21, pp. 2022-2033. https://doi.org/10.1161/CIRCULATIONAHA.117.028351
Letter
Guo, J, Lodge, K, Newnham, M, Bunclark, K, Toshner, M, Morrell, NW & Li, W 2018, 'Increased antielastase activity in idiopathic pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension', American Journal of Respiratory Cell and Molecular Biology, vol. 59, no. 5, pp. 652-655. https://doi.org/10.1165/rcmb.2018-0060LE
Newnham, M, Hernandez-Sanchez, J, Dunning, J, Ng, C, Tsui, S, Bunclark, K, Sheares, K, Taboada, D, Toshner, M, Pepke-Zaba, J, Jenkins, D & Cannon, J 2017, 'Age should not be a barrier for pulmonary endarterectomy in carefully selected patients', European Respiratory Journal, vol. 50, no. 6, 1701804. https://doi.org/10.1183/13993003.01804-2017
Review article
Balbirsingh, V, Mohammed, AS, Turner, A & Newnham, M 2022, 'Cardiovascular disease in chronic obstructive pulmonary disease: a narrative review', Thorax, vol. 77, no. 9, pp. 939-945. https://doi.org/10.1136/thoraxjnl-2021-218333
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