Dr Anita Pye

Dr Anita Pye

Institute of Applied Health Research
Post-doctoral Research Fellow
Clinical Trials Co-ordinator

Contact details

University of Birmingham
B15 2TT

Anita Pye works predominantly in respiratory research and Phase 1 to 3 clinical trials looking at new treatments for alpha-1 antitrypsin deficiency and chronic obstructive pulmonary disease. She also has considerable experience of assessment of bacteria in chronic lung disease.


  • PhD, University of Birmingham, 1994
  • BSc (Hons) in Applied Biology, Trent Polytechnic, Nottingham, 1989
  • Level 2 Certificate in Leadership and Management


Anita has worked at the University of Birmingham since 1993 after completing a PhD looking at the assessment and characterisation of bacterial load in chronic lung disease. 

Since 2003 Anita has been organising and administering large and complex clinical research projects, including international, multi-centre clinical trials in alpha-1 antitrypsin deficiency, COPD and bronchiectasis. This involves contributing to the design, conduct, analysis, publication and presentation of clinical trials research. 

Anita has a wealth of experience of research ethics and working to Good Clinical Practice guidelines.


Personal Academic Tutor,  MSc/PGDip/PGCert Respiratory Medicine, 2020

Postgraduate supervision

PhD 2nd supervisor


Anita’s research activity is currently focused on lung disease in patients with alpha-1 antitrypsin deficiency, with a developing interest in liver disease that also occurs in this patient group. Previous research includes bacterial colonisation and exacerbations in chronic lung disease with a particular interest in non-typeable Haemophilus influenzae and Pseudomonas aeruginosa.

Other activities

  • Higher Education Mental Health First Aid Champion – March 2019
  • MDS Pilot Mentoring Scheme – September 2019
  • Involved with the organisation of the following conferences and networks:

- International multi-disciplinary meeting on COPD,  2000 - 2018

- West Midlands Acute Medicine Conference, 2017 onwards

  • Midlands Bronchiectasis Network Meetings, 2014 onwards


Quinn, M, Ellis, P, Pye, A & Turner, A 2020, 'Obstacles to early diagnosis and treatment of alpha-1 antitrypsin deficiency: current perspectives', Therapeutics and Clinical Risk Management

Pye, A & Turner, A 2019, 'Experimental and investigational drugs for the treatment of alpha-1 antitrypsin deficiency', Expert opinion on investigational drugs, vol. 28, no. 10, pp. 891-902. https://doi.org/10.1080/13543784.2019.1672656

Stone H, Pye A, Stockley RA. 2014. Disease associations in alpha-1-antitrypsin deficiency. Respir Med. 108(2):338-43. doi: 10.1016/j.rmed.2013.10.006.

Pye A, Hill SL, Bharadwa P, Stockley RA. 2008. Effect of storage and postage on recovery and quantitation of bacteria in sputum samples. J Clin Pathol. 61(3):352-4. doi: 10.1136/jcp.2007.051490.

Stockley RA, O'Brien C, Pye A, Hill SL. 2000. Relationship of sputum color to nature and outpatient management of acute exacerbations of COPD. Chest. 117(6):1638-45. doi: 10.1378/chest.117.6.1638.

View all publications in research portal