Recent publications
Article
Kerzeli, IK, Kostakis, A, Türker, P, Malmström, P-U, Hemdan, T, Mezheyeuski, A, Ward, DG, Bryan, RT, Segersten, U, Lord, M & Mangsbo, SM 2023, 'Elevated levels of MMP12 sourced from macrophages are associated with poor prognosis in urothelial bladder cancer', BMC Cancer, vol. 23, no. 1, 605. https://doi.org/10.1186/s12885-023-11100-0
James, N, Pirrie, S, Liu, W, Catto, J, Jefferson, K, Patel, P, Hughes, A, Pope, A, Nanton, V, Mintz, H, Knight, A, Gallagher, J & Bryan, R 2023, 'Image directed redesign of bladder cancer treatment pathways: the BladderPath RCT', Health Technology Assessment. <https://www.journalslibrary.nihr.ac.uk/HTA/#/>
The BladderPath trial management group 2023, 'Properties of non-coding mutation hotspots as urinary biomarkers for bladder cancer detection', Scientific Reports, vol. 13, no. 1, 1060. https://doi.org/10.1038/s41598-023-27675-4
Bryan, R, Pirrie, S, Abbotts, B, Maycock, S, During, V, Lewis, C, Grant, M, Bird, D, Devall, A, Wallace, DM, James, N, Billingham, L, Zeegers, M & Cheng, KK 2023, 'Selenium and vitamin E to prevent recurrence and progression in patients with non-muscle-invasive bladder cancer: the SELENIB randomized clinical trial: results of the SELENIB randomized clinical trial', JAMA network open. <https://jamanetwork.com/journals/jamanetworkopen>
Goel, A, Ward, DG, Noyvert, B, Yu, M, Gordon, NS, Abbotts, B, Colbourne, JK, Kissane, S, James, ND, Zeegers, MP, Cheng, KK, Cazier, J, Whalley, CM, Beggs, AD, Palles, C, Arnold, R & Bryan, RT 2022, 'Combined exome and transcriptome sequencing of non-muscle-invasive bladder cancer: associations between genomic changes, expression subtypes, and clinical outcomes', Genome medicine, vol. 14, no. 1, 59 . https://doi.org/10.1186/s13073-022-01056-4
Richters, A, Kiemeney, LALM, Mehra, N, Westgeest, HM, Birtle, A, Bryan, RT & Aben, KKH 2022, 'Evidence or prejudice? Critical re-analysis of randomized controlled trials comparing overall survival after cisplatin versus carboplatin-based regimens in advanced urothelial carcinoma', Clinical Genitourinary Cancer, vol. 20, no. 4, pp. e346-e352. https://doi.org/10.1016/j.clgc.2021.12.017
Galesloot, TE, Grotenhuis, AJ, Kolev, D, Aben, KK, Bryan, RT, Catto, JWF, Cheng, KK, Conroy, S, Dyrskjøt, L, Fleshner, NE, James, ND, Lamy, P, Lindskrog, SV, Malats, N, Mengual, L, Verhaegh, G, Zeegers, MP, Kiemeney, LALM & Vermeulen, SH 2022, 'Genome-wide meta-analysis identifies novel genes associated with recurrence and progression in non-muscle-invasive bladder cancer', European Urology Oncology, vol. 5, no. 1, pp. 70-83. https://doi.org/10.1016/j.euo.2021.07.001
BladderPath Trial Management Group 2022, 'Highly sensitive and specific detection of bladder cancer via targeted ultra-deep sequencing of urinary DNA', European Urology Oncology. https://doi.org/10.1016/j.euo.2022.03.005
Van Osch, F, Nekeman, D, Aaronson, N, Billingham, L, James, N, Cheng, K, Bryan, R & Zeegers, M 2022, 'Patients choose certainty over burden in bladder cancer surveillance', World Journal of Urology, vol. 37, no. 12, pp. 2747-2753. https://doi.org/10.1007/s00345-019-02728-4
Gordon, N, Humayun-Zakaria, N, Goel, A, Abbotts, B, Zeegers, MP, Cheng, KK, Arnold, R, James, ND, Bryan, R & Ward, D 2022, 'STAG2 protein expression in non-muscle-invasive bladder cancer: associations with sex, genomic and transcriptomic changes, and clinical outcomes', European Urology Open Science, vol. 38, pp. 88-95. https://doi.org/10.1016/j.euros.2022.02.004
Comment/debate
Nanton, V, Bryan, R, Pope, A, Hughes, A, Jefferson, K, Catto, J, Knight, A, Gallagher, J, Mintz, H, Pirrie, S, Liu, W, Young, A, Patel, P & James, N 2023, 'Boosting and broadening recruitment to UK cancer trials: towards a blueprint for action.', BMJ Oncology.
Editorial
Mintz, HP, Dosanjh, ARS, Parsons, H, Sydes, M, Bryan, RT, James, ND & Patel, P 2023, 'Making administrative healthcare systems clinical data the future of clinical trials: lessons from BladderPath', BMJ Oncology, vol. 2, no. 1, e000038. https://doi.org/10.1136/bmjonc-2023-000038
Review article
Toren, P, Wilkins, A, Patel, K, Burley, A, Gris, T, Kockelbergh, R, Lodhi, T, Choudhury, A & Bryan, RT 2023, 'The sex gap in bladder cancer survival: a missing link in bladder cancer care?', Nature reviews. Urology. https://doi.org/10.1038/s41585-023-00806-2
Unsworth-White, S, Kitchen, M & Bryan, R 2022, 'Immunotherapy for non-muscle invasive bladder cancer: from the origins of BCG to novel therapies', Future Oncology, vol. 18, no. 1, pp. 105-115. https://doi.org/10.2217/fon-2021-0781
Ward, K, Kitchen, M, Mathias, S-J, Khanim, F & Bryan, R 2022, 'Novel intravesical therapeutics in the treatment of non-muscle invasive bladder cancer: horizon scanning', Frontiers in Surgery, vol. 9, 912438. https://doi.org/10.3389/fsurg.2022.912438
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