Recent publications
Article
BladderPath Collaborative Group, Bryan, RT, Liu, W, Pirrie, SJ, Amir, R, Gallagher, J, Hughes, A, Jefferson, KP, Knight, A, Nanton, V, Mintz, H, Pope, AM, Cherian, J, Ekwueme, K, Gommersall, L, Hellawell, G, Hunter-Campbell, P, Kandaswamy, GV, Kotwal, S, Kumar, V, Mak, D, Mohee, A, Nambirajan , T, Ward, DG, Kennish, S, Catto, J, Patel, P & James, ND 2025, 'Randomized Comparison of Magnetic Resonance Imaging Versus Transurethral Resection for Staging New Bladder Cancers: Results From the Prospective BladderPath Trial', Journal of Clinical Oncology . https://doi.org/10.1200/JCO.23.02398
James, N, Pirrie, S, Liu, W, Catto, J, Jefferson, K, Patel, P, Hughes, A, Pope, A, Nanton, V, Mintz, HP, Knight, A, Gallagher, J & Bryan, RT 2024, 'Image directed redesign of bladder cancer treatment pathways: the BladderPath RCT', Health Technology Assessment, vol. 28, no. 42, pp. 1-65. https://doi.org/10.3310/DEHT5407
Birtle, A, Jones, R, Chester, J, Lewis, R, Biscombe, K, Johnson, M, Blacker, A, Bryan, R, Catto, JWF, Choudhury, A, Das, P, Jagdev, S, Powles, T, Wagstaff, J, Chung, KC, Cafferty, F & Hall, EC 2024, 'Improved Disease Free Survival With Adjuvant Chemotherapy After Nephroureterectomy for Upper Tract Urothelial Cancer: Final Results of the POUT Trial', Journal of Clinical Oncology . https://doi.org/10.1200/JCO.23.01659
Sankin, A, Dave, P, Cherrill, L-R, Boucher, RH, Zeegers, MP, Cheng, KK, James, ND, Agalliu, I & Bryan, RT 2024, 'Low-grade urothelial carcinoma recurs at a tempo that naturally accelerates over time', Urology. https://doi.org/10.1016/j.urology.2024.07.017
Kerzeli, IK, Kostakis, A, Türker, P, Malmström, P-U, Hemdan, T, Mezheyeuski, A, Ward, DG, Bryan, RT, Segersten, U, Lord, M & Mangsbo, SM 2023, 'Elevated levels of MMP12 sourced from macrophages are associated with poor prognosis in urothelial bladder cancer', BMC Cancer, vol. 23, no. 1, 605. https://doi.org/10.1186/s12885-023-11100-0
The BladderPath trial management group 2023, 'Properties of non-coding mutation hotspots as urinary biomarkers for bladder cancer detection', Scientific Reports, vol. 13, no. 1, 1060. https://doi.org/10.1038/s41598-023-27675-4
SELENIB Investigators, Bryan, R, Pirrie, S, Abbotts, B, Maycock, S, During, V, Lewis, C, Grant, M, Bird, D, Devall, A, Wallace, DM, James, N, Billingham, L, Zeegers, M & Cheng, KK 2023, 'Selenium and Vitamin E for Prevention of Non–Muscle-Invasive Bladder Cancer Recurrence and Progression: A Randomized Clinical Trial', JAMA network open, vol. 6, no. 10, e2337494. https://doi.org/10.1001/jamanetworkopen.2023.37494
Comment/debate
Unsworth-White, S, Humayun-Zakaria, N & Bryan, RT 2025, 'Balancing risks and benefits in the treatment of patients with Bacillus Calmette-Guerin-unresponsive high-risk non-muscle-invasive bladder cancer', Translational Andrology and Urology, vol. 14, no. 1, pp. 1-3. https://doi.org/10.21037/tau-24-529
Bryan, RT, Patel, P, Kennish, SJ, Catto, JWF, James, ND & BladderPath Collaborative Group 2025, 'Improving the pathway to correct treatment for patients with muscle-invasive bladder cancer: exploring the myths around the BladderPath trial', BJU International . https://doi.org/10.1111/bju.16728
Ward, D & Bryan, R 2025, 'Should We Incorporate Urinary Tumour DNA Status in Treatment Decisions for Patients with Non–muscle-invasive Bladder Cancer?', European urology.
Editorial
Mintz, HP, Dosanjh, ARS, Parsons, H, Sydes, M, Bryan, RT, James, ND & Patel, P 2023, 'Making administrative healthcare systems clinical data the future of clinical trials: lessons from BladderPath', BMJ Oncology, vol. 2, no. 1, e000038. https://doi.org/10.1136/bmjonc-2023-000038
Letter
Collett, G, Bashford, T, Whitehead, NJ, Kazimierska, E, Swamy, GVK, Jones, RJ, Van Hemelrijck, M & Bryan, RT 2025, 'Occupational incidence of bladder cancer amongst veteran ammunition technicians of the British Army', BJU International . https://doi.org/10.1111/bju.16678
Yu, M, Goel, A, Tura, B, Whalley, CM, Cheng, KK, Zeegers, MP, James, ND, Dyrskjøt, L, Ward, DG, Bryan, RT & Arnold, R 2025, 'Towards Epigenetic-based Subtyping of Bladder Cancer: DNA Methylation Predicts Molecular Subtypes of Non-muscle-invasive Bladder Cancer', European urology, vol. 87, no. 5, pp. 579-581. https://doi.org/10.1016/j.eururo.2025.02.011
Gordon, NS, McGuigan, EK, Ondasova, M, Knight, J, Baxter, LA, Ott, S, Hastings, RK, Zeegers, MP, James, ND, Cheng, KK, Goel, A, Yu, M, Arnold, R, Bryan, RT & Ward, DG 2024, 'Comparison and combination of mutation and methylation-based urine tests for bladder cancer detection', Biomarker Research, vol. 12, no. 1, 133. https://doi.org/10.1186/s40364-024-00682-x
Review article
Nanton, V, Bryan, R, Pope, A, Hughes, A, Jefferson, K, Catto, J, Knight, A, Gallagher, J, Mintz, H, Pirrie, S, Liu, W, Young, A, Patel, P & James, N 2023, 'Boosting and broadening recruitment to UK cancer trials: towards a blueprint for action', BMJ Oncology, vol. 2, no. 1, e000092. https://doi.org/10.1136/bmjonc-2023-000092
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