Recent publications
Article
Kingsley, G, Skagia, A, Passaretti, P, Fernandez-Cuesta, C, Reynolds-Winczura, A, Koscielniak, K & Gambus, A 2023, 'DONSON facilitates Cdc45 and GINS chromatin association and is essential for DNA replication initiation', Nucleic Acids Research. https://doi.org/10.1093/nar/gkad694
Scaramuzza, S, Jones, RM, Sadurni, MM, Reynolds-Winczura, A, Poovathumkadavil, D, Farrell, A, Natsume, T, Rojas, P, Cuesta, CF, Kanemaki, MT, Saponaro, M & Gambus, A 2023, 'TRAIP resolves DNA replication-transcription conflicts during the S-phase of unperturbed cells', Nature Communications, vol. 14, no. 1, 5071. https://doi.org/10.1038/s41467-023-40695-y
Cvetković, M, Passaretti, P, Butryn, A, Reynolds-Winczura, A, Kingsley, G, Skagia, A, Fernandez-Cuesta, C, Poovathumkadavil, D, George, R, Chauhan, A, Jhujh, S, Stewart, G, Gambus, A & Costa, A 2023, 'The structural mechanism of dimeric DONSON in replicative helicase activation', Molecular Cell, vol. 83, no. 22, pp. 4017-4031.e9. https://doi.org/10.1016/j.molcel.2023.09.029
Tarcan, Z, Poovathumkadavil, D, Skagia, A & Gambus, A 2022, 'The p97 segregase cofactor Ubxn7 facilitates replisome disassembly during S-phase', The Journal of biological chemistry, vol. 298, no. 8, 102234. https://doi.org/10.1016/j.jbc.2022.102234
Blakemore, D, Vilaplana-Lopera, N, Almaghrabi, R, Gonzalez, E, Moya, M, Ward, C, Murphy, G, Gambus, A, Petermann, E, Stewart, GS & García, P 2021, 'MYBL2 and ATM suppress replication stress in pluripotent stem cells', EMBO Reports, vol. 22, no. 5, e51120. https://doi.org/10.15252/embr.202051120
Hadzhiev, Y, Qureshi, HK, Wheatley, L, Cooper, L, Jasiulewicz, A, Van Nguyen, H, Wragg, JW, Poovathumkadavil, D, Conic, S, Bajan, S, Sik, A, Hutvàgner, G, Tora, L, Gambus, A, Fossey, JS & Müller, F 2019, 'A cell cycle-coordinated Polymerase II transcription compartment encompasses gene expression before global genome activation', Nature Communications, vol. 10, no. 1, 691, pp. 691. https://doi.org/10.1038/s41467-019-08487-5
Moreno, SP, Jones, RM, Poovathumkadavil, D, Scaramuzza, S & Gambus, A 2019, 'Mitotic replisome disassembly depends on TRAIP ubiquitin ligase activity', Life Science Alliance, vol. 2, no. 2, e201900390. https://doi.org/10.26508/lsa.201900390
Sonnerville, R, Priego Moreno, S, Knebel, A, Johnson, C, Hastle, CJ, Gartner, A, Gambus, A & Labib, K 2017, 'CUL-2LRR-1 and UBXN-3 drive replisome disassembly during DNA replication termination and mitosis', Nature Cell Biology, vol. 19, pp. 468–479. https://doi.org/10.1038/ncb3500
Chadha, GS, Gambus, A, Gillespie, PJ & Blow, JJ 2016, 'Xenopus Mcm10 is a CDK-substrate required for replication fork stability', Cell Cycle, vol. 15, no. 16, pp. 2183-2195. https://doi.org/10.1080/15384101.2016.1199305
Moreno, SP & Gambus, A 2015, 'Regulation of Unperturbed DNA Replication by Ubiquitylation', Genes, vol. 6, no. 3, pp. 451-468. https://doi.org/10.3390/genes6030451
Bailey, R, Priego Moreno, S & Gambus, A 2015, 'Termination of DNA replication forks: "Breaking up is hard to do"', Nucleus (Austin), vol. 6, no. 3, pp. 187-196. https://doi.org/10.1080/19491034.2015.1035843
Chapter (peer-reviewed)
Gambus, A 2018, Termination of Eukaryotic Replication Forks. in DNA Replication: From Old Principles to New Discoveries. vol. 1042, Advances in Experimental Medicine and Biology, vol. 1042, Springer, pp. 163-187. https://doi.org/10.1007/978-981-10-6955-0_8
Chapter
De Piccoli, G & Gambus, A 2016, Role of Small-Molecule Modifiers in Replication Initiation. in DL Kaplan (ed.), The Initiation of DNA Replication in Eukaryotes. Springer, pp. 343-370. https://doi.org/10.1007/978-3-319-24696-3_17
Review article
Moreno, SP & Gambus, A 2020, 'Mechanisms of eukaryotic replisome disassembly', Biochemical Society Transactions, vol. 48, no. 3, pp. 823-836. https://doi.org/10.1042/BST20190363
Working paper
Gambus, A, Moreno, SP, Jones, RM & Poovathumkadavil, D 2018 'Mitotic replisome disassembly in vertebrates' bioRxiv, pp. 1-27. https://doi.org/10.1101/418368
View all publications in research portal