Recent publications
Article
Experimental Cancer Medicine Centres (ECMC) CID trials working group, Blagden, SP, Yu, L-M, Ellis, S, Hughes, H, Shaaban, A, Fennelly-Barnwell, J, Lythgoe, MP, Cooper, AM, Maignen, FM, Buckland, SW, Kearns, PR & Brown, LC 2023, 'Additional consensus recommendations for conducting complex innovative trials of oncology agents: a post-pandemic perspective', British Journal of Cancer, vol. 128, no. 3, pp. 474-477. https://doi.org/10.1038/s41416-022-02051-7
de Rojas, T, Kearns, P, Blanc, P, Skolnik, J, Fox, E, Knox, L, Rousseau, R, Doz, F, Bird, N, Pearson, AJ & Vassal, G 2023, 'Changing incentives to ACCELERATE drug development for paediatric cancer', Cancer Medicine, vol. 12, no. 7, pp. 8825-8837. https://doi.org/10.1002/cam4.5627
Moreno, L, DuBois, SG, Glade Bender, J, Mauguen, A, Bird, N, Buenger, V, Casanova, M, Doz, F, Fox, E, Gore, L, Hawkins, DS, Izraeli, S, Jones, DTW, Kearns, PR, Molenaar, JJ, Nysom, K, Pfister, S, Reaman, G, Smith, M, Weigel, B, Vassal, G, Zwaan, CM, Paoletti, X, Iasonos, A & Pearson, ADJ 2023, 'Combination Early-Phase Trials of Anticancer Agents in Children and Adolescents', Journal of Clinical Oncology . https://doi.org/10.1200/JCO.22.02430
Retzer, A, Baddeley, E, Sivell, S, Scott, H, Nelson, A, Bulbeck, H, Seddon, K, Grant, R, Adams, R, Watts, C, Aiyegbusi, OL, Kearns, P, Cruz Rivera, S, Dirven, L, Calvert, M & Byrne, A 2023, 'Development of a core outcome set for use in adult primary glioma phase III interventional trials: A mixed methods study', Neuro-oncology advances. https://doi.org/10.1093/noajnl/vdad096
PITCH Consortium, CONSENSUS & OCTAVE Collaborative Group 2023, 'SARS-CoV-2-specific immune responses and clinical outcomes after COVID-19 vaccination in patients with immune-suppressive disease', Nature Medicine. https://doi.org/10.1038/s41591-023-02414-4
Aggarwal, A, Choudhury, A, Fearnhead, NS, Kearns, P, Kirby, A, Lawler, M, Quinlan, S, Palmieri, C, Roques, T, Simcock, R, Walter, FM, Price, P & Sullivan, R 2023, 'The future of cancer care in the UK—time for a radical and sustainable National Cancer Plan', The Lancet Oncology. https://doi.org/10.1016/S1470-2045(23)00511-9
Millen, GC, Arnold, R, Cazier, J-B, Curley, H, Feltbower, R, Gamble, A, Glaser, A, Grundy, RG, Kirton, L, Lee, LYW, McCabe, MG, Palles, C, Phillips, B, Stiller, CA, Varnai, C & Kearns, P 2022, 'COVID-19 in children with haematological malignancies', Archives of Disease in Childhood, vol. 107, no. 2, pp. 186-188. https://doi.org/10.1136/archdischild-2021-322062
Retzer, A, Sivell, S, Scott, H, Nelson, A, Bulbeck, H, Seddon, K, Grant, R, Adams, R, Watts, C, Aiyegbusi, OL, Kearns, P, Cruz Rivera, S, Dirven, L, Baddeley, E, Calvert, M & Byrne, A 2022, 'Development of a core outcome set and identification of patient-reportable outcomes for primary brain tumour trials: protocol for the COBra study', BMJ open, vol. 12, no. 9, e057712, pp. e057712. https://doi.org/10.1136/bmjopen-2021-057712
Essential Medicines Group, Otth, M, Brack, E, Kearns, PR, Kozhaeva, O, Ocokoljic, M, Schoot, RA & Vassal, G 2022, 'Essential medicines for childhood cancer in Europe: a pan-European, systematic analysis by SIOPE', The Lancet Oncology, vol. 23, no. 12, pp. 1537-1546. https://doi.org/10.1016/S1470-2045(22)00623-4
Nohtani, M, Vrzalikova, K, Ibrahim, M, Powell, JE, Fennell, É, Morgan, S, Grundy, R, McCarthy, K, Dewberry, S, Bouchal, J, Bouchalova, K, Kearns, P & Murray, PG 2022, 'Impact of Tumour Epstein-Barr Virus Status on Clinical Outcome in Patients with Classical Hodgkin Lymphoma (cHL): A Review of the Literature and Analysis of a Clinical Trial Cohort of Children with cHL', Cancers, vol. 14, no. 17. https://doi.org/10.3390/cancers14174297
CATALYST investigators, Fisher, B, Veenith, T, Slade, D, Gaskell, C, Rowland, M, Whitehouse, T, Scriven, J, Parekh, D, Balasubramaniam, M, Cooke, G, Morley, N, Gabriel, Z, Wise, M, Porter, J, McShane, H, Ho, L-P, Newsome, P, Rowe, A, Sharpe, R, Thickett, D, Bion, J, Gates, S, Richards, D, Kearns, P & Mussai, F 2022, 'Namilumab or infliximab compared with standard of care in hospitalised patients with COVID-19 (CATALYST): a randomised, multicentre, multi-arm, multistage, open-label, adaptive, phase 2, proof-of-concept trial', The Lancet Respiratory Medicine, vol. 10, no. 3, pp. 255-266. https://doi.org/10.1016/S2213-2600(21)00460-4, https://doi.org/10.1016/s2213-2600(21)00460-4
the QUARTET Project and the SIOPE Radiation Oncology Working Group 2022, 'QUARTET: a SIOP Europe project for quality and excellence in radiotherapy and imaging for children and adolescents with cancer', European Journal of Cancer , vol. 172, pp. 209-220. https://doi.org/10.1016/j.ejca.2022.05.037
Comment/debate
Pritchard-Jones, K, Challinor, JM, Hunger, SP, Sung, L, Davidson, A, Morrissey, LK, Khan, MS, Dalvi, RB, Sullivan, MJ, Hessissen, L, Chantada, GL, Kearns, P, Frazier, AL, Wollaert, S & Laub, T 2022, 'SIOP Strategy 2021-2025: cure for more, care for all', Pediatric Blood & Cancer, vol. 69, no. 6, e29577. https://doi.org/10.1002/pbc.29577
Letter
O’Connor, D, Joy, M, Enshaei, A, Kirkwood, A, Kearns, PR, Samarasinghe, S, Moppett, J, Moorman, AV & Vora, A 2023, 'Cranial radiotherapy has minimal benefit in children with central nervous system involvement in T-ALL', Blood Advances. https://doi.org/10.1182/bloodadvances.2023011267
Review article
Major, A, Palese, M, Ermis, E, James, A, Villarroel, M, Klussmann, FA, Hessissen, L, Geel, J, Khan, MS, Dalvi, R, Sullivan, M, Kearns, P, Frazier, AL, Pritchard-Jones, K, Nakagawara, A, Rodriguez-Galindo, C & Volchenboum, SL 2022, 'Mapping Pediatric Oncology Clinical Trial Collaborative Groups on the Global Stage', JCO Global Oncology, vol. 8, e2100266. https://doi.org/10.1200/GO.21.00266
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