Recent publications
Article
Otth, M, de Rojas, T, Rauwolf, KK, Martins, M, Dirksen, U, Heenen, D, Kameric, L, Kearns, P, Ladenstein, R, Owens, C, Queiroz, C, Sullivan, R, Rizzari, C & Vassal, G 2025, 'Differences in care delivery for children and adolescents with cancer in Europe – results from the SIOPE OCEAN project', EJC Paediatric Oncology. https://doi.org/10.1016/j.ejcped.2025.100219
van Kuijk, A, Kearns, P & Burke, GAA 2025, 'Immunotherapy for Paediatric Diffuse Large B-Cell Lymphoma: A Review of Current Clinical Trials and Future Directions', EJC Paediatric Oncology, vol. 5, 100228. https://doi.org/10.1016/j.ejcped.2025.100228
Brugha, R, Kirkham, A, Bate, J, Burke, GAA, Hughes, A, Magwaro, S, Pope, AM, Beesley, R, Lax, S, Kelly, E, Greenland, M, Minassian, AM, Liu, X, Billingham, L, McInnes, I, Goodyear, CS, Kearns, P, Wedderburn, LR & OCTAVE-Minor Collaborative Group 2026, 'SARS-CoV-2-Specific Immune Responses to Vaccination in Children and Adolescents with Suppressed Immune Systems: A Prospective, Observational Study', The Journal of pediatrics, vol. 289, 114873. https://doi.org/10.1016/j.jpeds.2025.114873
George, SL, Lynn, C, Stankunaite, R, Hughes, D, Sauer, CM, Chalker, J, Waqar Ahmed, S, Oostveen, M, Proszek, PZ, Yuan, L, Shaikh, R, Jamal, S, Brew, A, Tall, J, Rogers, T, Clifford, SC, Vormoor, J, Shipley, JM, Tweddle, DA, Jones, C, Willis, C, Burke, GAA, Vedi, A, Howell, L, Johnston, R, Rees, H, Adams, M, Jesudason, A, Ronghe, M, Elliott, M, Ross, E, Makin, G, Campbell-Hewson, Q, Grundy, RG, Turnbull, J, Wilson, S, Lee, V, Gray, JC, Stoneham, S, Gatz, SA, Marshall, LV, Angelini, P, Anderson, J, Cresswell, GD, Graham, TA, Al-Lazikani, B, Cortés-Ciriano, I, Kearns, P, Hutchinson, JC, Hargrave, D, Jacques, TS, Hubank, M, Sottoriva, A & Chesler, L 2025, 'Stratified Medicine Pediatrics: Cell-Free DNA and Serial Tumor Sequencing Identifies Subtype-Specific Cancer Evolution and Epigenetic States', Cancer Discovery, vol. 15, no. 4, pp. 717-732. https://doi.org/10.1158/2159-8290.CD-24-0916
Otth, M, Ocokoljic, M, Armenkova, T, Ban, I, Essiaf, S, Hopfgartner, M, Kameric, L, Kearns, PR, Kokkinou, G, Rizzari, C, Schneider, C & Scheinemann, K 2025, 'The Healthcare Professionals’ and Patient Advocates’ Perspectives on the Care for Children with Cancer in Europe: A Report from the ESCALIER Project', Current Oncology, vol. 32, no. 2, 84. https://doi.org/10.3390/curroncol32020084
Innovative Therapies for Children with Cancer (ITCC) Consortium & European Association for Neuroblastoma Research (SIOPEN) 2024, 'Bevacizumab, Irinotecan, or Topotecan Added to Temozolomide for Children With Relapsed and Refractory Neuroblastoma: Results of the ITCC-SIOPEN BEACON-Neuroblastoma Trial', Journal of Clinical Oncology. https://doi.org/10.1200/JCO.23.00458
Syrimi, E, Khan, N, Murray, P, Willcox, C, Haigh, T, Willcox, B, Masand, N, Bowen, C, Dimakou, DB, Zuo, J, Barone, SM, Irish, JM, Kearns, P & Taylor, GS 2024, 'Defects in NK cell immunity of pediatric cancer patients revealed by deep immune profiling', iScience. https://doi.org/10.1016/j.isci.2024.110837
Innovative Therapies for Children with Cancer (ITCC) Consortium 2024, 'Evolution of the Innovative Therapies for Children With Cancer Consortium Trial Portfolio for Drug Development for Children With Cancer', Journal of Clinical Oncology , pp. JCO2301237. https://doi.org/10.1200/JCO.23.01237
Chisholm, J, Mandeville, H, Adams, M, Minard-Collin, V, Rogers, T, Kelsey, A, Shipley, J, van Rijn, RR, de Vries, I, van Ewijk, R, de Keizer, B, Gatz, SA, Casanova, M, Hjalgrim, LL, Firth, C, Wheatley, K, Kearns, P, Liu, W, Kirkham, A, Rees, H, Bisogno, G, Wasti, A, Wakeling, S, Heenen, D, Tweddle, DA, Merks, JHM, Jenney, M & Heymann, D (ed.) 2024, 'Frontline and Relapsed Rhabdomyosarcoma (FAR-RMS) Clinical Trial: A Report from the European Paediatric Soft Tissue Sarcoma Study Group (EpSSG)', Cancers, vol. 16, no. 5, 998. https://doi.org/10.3390/cancers16050998
PITCH Consortium, OCTAVE Collaborative Group, OCTAVE‐DUO Investigators, PROSECO Investigators, Colton, H, Barratt, N, Temperton, N, Hornsby, H, Angyal, A, Grouneva, I, Lindsey, BB, Kearns, P, Barnes, E, Goodyear, CS, Richter, A, Thomas, D, Cook, G, McInnes, IB, Willicombe, M, Siebert, S, Orchard, K, Selby, R, Bowden, S, Collini, PJ, Pope, A, Kirkham, A, Kronsteiner, B, Dunachie, SJ, Miller, P, Clay, J, Hurst, E, Malladi, R, Kesavan, M, Kinsella, F, Sanderson, R, Yong, KL, Rea, D, Parry, H, Lim, SH, Snowden, JA & de Silva, TI 2024, 'Greater preservation of SARS-CoV-2 neutralising antibody responses following the ChAdOx1-S (AZD1222) vaccine compared to mRNA vaccines in haematopoietic cell transplant recipients', British Journal of Haematology, vol. 205, no. 6, pp. 2206-2218. https://doi.org/10.1111/bjh.19874
OCTAVE-DUO investigators & Parry, H 2024, 'Immunogenicity of third dose COVID-19 vaccine strategies in patients who are immunocompromised with suboptimal immunity following two doses (OCTAVE-DUO): an open-label, multicentre, randomised, controlled, phase 3 trial', The Lancet Rheumatology, vol. 6, no. 6, pp. E339-E351. https://doi.org/10.1016/S2665-9913(24)00065-1
Perry, TA, Masand, N, Vrzalikova, K, Pugh, M, Wei, W, Hollows, R, Bouchalova, K, Nohtani, M, Fennell, E, Bouchal, J, Kearns, P & Murray, PG 2024, 'The Oncogenic Lipid Sphingosine-1-Phosphate Impedes the Phagocytosis of Tumor Cells by M1 Macrophages in Diffuse Large B Cell Lymphoma', Cancers, vol. 16, no. 3, 574. https://doi.org/10.3390/cancers16030574
Comment/debate
Chisholm, J, Mandeville, H, Adams, M, Minard-Collin, V, Rogers, T, Kelsey, A, Shipley, J, van Rijn, RR, de Vries, I, van Ewijk, R, de Keizer, B, Gatz, SA, Casanova, M, Hjalgrim, LL, Firth, C, Wheatley, K, Kearns, P, Liu, W, Kirkham, A, Rees, H, Bisogno, G, Wasti, A, Wakeling, S, Heenen, D, Tweddle, DA, Merks, JHM & Jenney, M 2024, 'Correction: Chisholm et al. Frontline and Relapsed Rhabdomyosarcoma (FaR-RMS) Clinical Trial: A Report from the European Paediatric Soft Tissue Sarcoma Study Group (EpSSG). Cancers 2024, 16, 998', Cancers, vol. 16, no. 19, 3427. https://doi.org/10.3390/cancers16193427
Wilson, JS, Main, C, Thorp, N, Taylor, RE, Majothi, S, Kearns, PR, English, M, Dandapani, M, Phillips, R, Wheatley, K & Pizer, B 2024, 'Correction to: The effectiveness and safety of proton beam radiation therapy in children and young adults with Central Nervous System (CNS) tumours: a systematic review', Journal of Neuro-Oncology. https://doi.org/10.1007/s11060-024-04612-7
Review article
Wilson, JS, Main, C, Thorp, N, Taylor, RE, Majothi, S, Kearns, PR, English, M, Dandapani, M, Phillips, R, Wheatley, K & Pizer, B 2024, 'The effectiveness and safety of proton beam radiation therapy in children and young adults with Central Nervous System (CNS) tumours: a systematic review', Journal of Neuro-Oncology. https://doi.org/10.1007/s11060-023-04510-4
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