Recent publications
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Fu, T, Scheffler, P, Forner, D, Noel, C, Huang, SH, Gilbert, R, Goldstein, D, O'Sullivan, B, Mehanna, H, Waldron, J & de Almeida, J 2021, 'A cost-utility analysis comparing CT surveillance, PET-CT surveillance, and planned postradiation neck dissection for advanced nodal HPV-positive oropharyngeal cancer', Cancer. https://doi.org/10.1002/cncr.33653
Bresadola, L, Weber, D, Ritzel, C, Lower, M, Bukur, V, Akilli-Öztürk, Ö, Becke, J, Mehanna, H, Schrörs, B, Vascotto, F, Sahin, U & Kong, A 2021, 'Comprehensive genomic and transcriptomic analysis of three synchronous primary tumours and a recurrence from a head and neck cancer patient', International Journal of Molecular Sciences, vol. 22, no. 14, 7583. https://doi.org/10.3390/ijms22147583
Pansini, PF, do Valle, IB, Damasceno, TCD, de Abreu, PM, Có, ACG, López, RVM, Lenzi, J, Rocha, RM, Souza, ED, Curado, MP, Mehanna, H, Nankivell, P, de Podestá, JRV & von Zeidler, SV 2021, 'Differential expression of potential biomarkers of oral squamous cell carcinoma development', Head and Neck Pathology. https://doi.org/10.1007/s12105-021-01322-8
Mehanna, H 2021, 'Dose-Escalated Intensity Modulated Radiotherapy in Patients with Locally-Advanced Laryngeal and Hypopharyngeal Cancers: ART DECO, a Phase 3 Randomised Controlled Trial', European Journal of Cancer.
Fouad, S, Landini, G, Robinson, M, Song, M & Mehanna, H 2021, 'Human papilloma virus detection in oropharyngeal carcinomas with in situ hybridisation using hand crafted morphological features and deep central attention residual networks', Computerized Medical Imaging and Graphics, vol. 88, 101853. https://doi.org/10.1016/j.compmedimag.2021.101853
Vreugdenhil, M, Fong, C, Sanghera, P, Hartley, A, Dunn, J & Mehanna, H 2021, 'Hypofractionated chemoradiation for head and cancer: data from the PET NECK trial', Oral Oncology, vol. 113, 105112. https://doi.org/10.1016/j.oraloncology.2020.105112
Batis, N, Brooks, J, Payne, K, Sharma, N, Nankivell, P & Mehanna, H 2021, 'Lack of predictive tools for conventional and targeted cancer therapy: barriers to biomarker development and clinical translation', Advanced Drug Delivery Reviews. https://doi.org/10.1016/j.addr.2021.113854
Carsuzaa, F, Lapeyre, M, Gregoire, V, Maingon, P, Beddok, A, Marcy, P, Salleron, J, Coutte, A, Racadot, S, Pointreau, Y, Graff, P, Beadle, B, Benezery, K, Biau, J, Calugaru, V, Castelli, J, Chua, M, Di Rito, A, Dore, M, Ghadjar, P, Huguet, F, Jardel, P, Johansen, J, Kimple, R, Krengli, M, Laskar, S, Mcdowell, L, Nichols, A, Tribius, S, Valduvieco, I, Hu, C, Liem, X, Moya-plana, A, D'onofrio, I, Parvathanen, U, Takiar, V, Orlandi, E, Psyrri, A, Shenouda, G, Sher, D, Steuer, C, Shan Sun, X, Tao, Y, Thomson, D, Tsai, M, Vulquin, N, Gorphe, P, Mehanna, H, Yom, SS, Bourhis, J & Thariat, J 2021, 'Recommendations for postoperative radiotherapy in head & neck squamous cell carcinoma in the presence of flaps: a GORTEC internationally-reviewed HNCIG-endorsed consensus', Radiotherapy & Oncology. https://doi.org/10.1016/j.radonc.2021.04.026
Gorphe, P, Grandbastien, B, Dietz, A, Duvvuri, U, Ferris, R, Golusinski, W, Holsinger, F, Hosal, S, Lawson, G, Mehanna, H, Paleri, V, Shaw, R, Succo, G, Rene Leemans, C & Simon, C 2021, 'Safety and feasibility of surgery for oropharyngeal cancers during the SARS-CoV-2-pandemic', Frontiers in Oncology, vol. 11, 651123. https://doi.org/10.3389/fonc.2021.651123
Gleneadie, HJ, Baker, AH, Batis, N, Bryant, J, Jiang, Y, Clokie, SJH, Mehanna, H, Garcia, P, Gendoo, DMA, Roberts, S, Burley, M, Molinolo, AA, Gutkind, JS, Scheven, BA, Cooper, PR, Parish, JL, Khanim, FL & Wiench, M 2021, 'The anti-tumour activity of DNA methylation inhibitor 5-aza-2′-deoxycytidine is enhanced by the common analgesic paracetamol through induction of oxidative stress', Cancer Letters, vol. 501, pp. 172-186. https://doi.org/10.1016/j.canlet.2020.12.029
Matos, LL, Forster, CHQ, Marta, GN, Castro Junior, G, Ridge, JA, Hirata, D, Miranda-Filho, A, Hosny, A, Sanabria, A, Gregoire, V, Patel, SG, Fagan, JJ, D'Cruz, AK, Licitra, L, Mehanna, H, Hao, S-P, Psyrri, A, Porceddu, S, Galloway, TJ, Golusinski, W, Lee, NY, Shiguemori, EH, Matieli, JE, Shiguemori, APAC, Diamantino, LR, Schiaveto, LF, Leão, L, Castro, AF, Carvalho, AL & Kowalski, LP 2021, 'The hidden curve behind COVID-19 outbreak: the impact of delay in treatment initiation in cancer patients and how to mitigate the additional risk of dying-the head and neck cancer model', Cancer Causes & Control, vol. 32, no. 5, pp. 459-471. https://doi.org/10.1007/s10552-021-01411-7
Whalley, C, Payne, K, Domingo, E, Blake, A, Richman, S, Brooks, J, Batis, N, Spruce, R, Consortium, SC, Mehanna, H, Nankivell, P & Beggs, A 2021, 'Ultra-low DNA Input into whole genome methylation assays and detection of oncogenic methylation and copy number variants in circulating tumour DNA', Epigenomes, vol. 5, no. 1, 6. https://doi.org/10.3390/epigenomes5010006
Soares-lima, SC, Mehanna, H, Camuzi, D, De Souza-santos, PT, Simão, TDA, Nicolau-neto, P, Almeida Lopes, MDS, Cuenin, C, Talukdar, FR, Batis, N, Costa, I, Dias, F, Degli Esposti, D, Boroni, M, Herceg, Z & Ribeiro Pinto, LF 2021, 'Upper aerodigestive tract squamous cell carcinomas show distinct overall DNA methylation profiles and different molecular mechanisms behind WNT signaling disruption', Cancers, vol. 13, no. 12, 3014. https://doi.org/10.3390/cancers13123014
Kong, A & Mehanna, H 2021, 'WEE1 inhibitor: clinical development', Current oncology reports, vol. 23, 107. https://doi.org/10.1007/s11912-021-01098-8
Preprint
Shaban, M, Raza, SEA, Hassan, M, Jamshed, A, Mushtaq, S, Loya, A, Batis, N, Brooks, J, Nankivell, P, Sharma, N, Robinson, M, Mehanna, H, Khurram, SA & Rajpoot, N 2021 'A digital score of tumour-associated stroma infiltrating lymphocytes predicts survival in head and neck squamous cell carcinoma'.
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