Recent publications
Article
Abou-Foul, AK, Kristunas, C, Henson, C, Andrew, D, Bidault, F, Dankbaar, JW, Gebrim, ES, de Graaf, P, Kim, J, King, AD, Kuno, H, Medrano-Martorell, S, Goh, JPN, Santos-Armentia, E, Schafigh, DG, Wu, XC, Xiao, Y, Huang, SH, Lydiatt, WM, Yu, E, Branstetter, BF & Mehanna, H 2026, 'Correlation between head and neck radiologists reporting on extranodal extension detected on radiological imaging: A head and neck cancer international group multinational study', Oral Oncology, vol. 178, 107980. https://doi.org/10.1016/j.oraloncology.2026.107980
Matheson, L, Watson, E, Fulton-Lieuw, T, Mittal, S, Gaunt, P, Sissons, J, Liaskou, E, Gaunt, C, Nankivell, P, Mehanna, H & Brett, J 2026, 'Promoting engagement in patient-initiated follow-up and self-care behaviours: acceptability of the 'ACT now & check-it-out' intervention for head and neck cancer (PETNECK2 study)', BMJ Open, vol. 16, no. 2, e099993. https://doi.org/10.1136/bmjopen-2025-099993
Southam, AD, Higginson, JA, Lloyd, GR, Smith, MJ, Cruchley-Fuge, LE, Spruce, R, Edbali, O, Weber, RJM, Mehanna, H & Batis, N 2026, 'Regional HNSCC metabolomics reveals widespread changes to one-carbon metabolism and S-adenosylmethionine metabolism across tumour core, tumour edge and adjacent non-tumour tissues', British Journal of Cancer. https://doi.org/10.1038/s41416-026-03410-4
Mehanna, H, Abou-Foul, AK, Henson, C, Kristunas, C, Nankivell, PC, McDowell, L, Leemans, CR, van den Brekel, MWM, von Buchwald, C, Jakobsen, KK, Grønhøj, C, Rasmussen, JH, Lydiatt, WM, Gupta, V, Branstetter, BF, Klussmann, JP, Wollenberg, B, Schmidl, B, Broglie, MA, Hendrickx, J-J, Awad, DR, Prestwich, R, Gaultier, A-L, Oliva, M, Nair, S, Noor, A, Krishnan, S, Iyizoba-Ebozue, Z, Sethi, M, Nauta, IH, Zhao, D & Yom, SS 2025, 'Accuracy and Prognosis of Extranodal Extension on Radiologic Imaging in Human Papillomavirus-Mediated Oropharyngeal Cancer: A Head and Neck Cancer International Group (HNCIG) Real-world Study', International Journal of Radiation: Oncology - Biology - Physics , vol. 123, no. 2, pp. 432-441. https://doi.org/10.1016/j.ijrobp.2025.04.003
Shephard, AJ, Mahmood, H, Raza, SEA, Araújo, ALD, Santos-Silva, AR, Lopes, MA, Vargas, PA, McCombe, KD, Craig, SG, James, J, Brooks, J, Nankivell, P, Mehanna, H, Khurram, SA & Rajpoot, NM 2025, 'Development and validation of an artificial intelligence-based pipeline for predicting oral epithelial dysplasia malignant transformation', Communications Medicine, vol. 5, 186. https://doi.org/10.1038/s43856-025-00873-z
Mehanna, H, Nankivell, P, Boelaert, K, Woolley, R, Sharma, N, Sidhu, PS, Madani, G, Da Forno, P, Moreman, C, Palmer, A, Fulton-Lieuw, T, Taylor, J, Rajaguru, K, Bekker, J, Vaidhyanath, R, Rehman, T & Deeks, J 2025, 'Diagnostic performance of ultrasound vs. ultrasound-guided FNAc in thyroid nodules: data from the ElaTION trial', The Journal of clinical endocrinology and metabolism, vol. 110, no. 7, dgae682, pp. 1997-2006. https://doi.org/10.1210/clinem/dgae682
Hillier, B, Waterboer, T, Brooks, J, Nankivell, P, Agarwal, R, Abou-Foul, A, Fulton-Lieuw, T, Kristunas, C, Vorsters, A, Cacciatore, P, Parish, J & Mehanna, H 2025, 'Efficacy of oral rinse and other detection methods in detecting oral human papillomavirus infections: the Oromouth cohort study', Journal of Infection. https://doi.org/10.1016/j.jinf.2025.106438
Kong, A, Hazell, M, Iqbal, G, Dunn, J & Mehanna, H 2025, 'Exploring the effect of differing centre hydration and anti-emetic policies on acute gastrointestinal and renal toxicities in the De-ESCALaTE trial', BJC Reports, vol. 3, 25. https://doi.org/10.1038/s44276-025-00132-7
Mahmood, H, Bradburn, M, Islam, NM, Kujan, O, Rajpoot, N, Santos-Silva, AR, Vargas, PA, James, J, Nankivell, P, Mehanna, H & Khurram, SA 2025, 'Independent Multicentre Validation of the ‘Six-Point’ Model for Malignant Transformation Risk in Oral Epithelial Dysplasia', Oral Diseases. https://doi.org/10.1111/odi.70173
Abstract
Cavalieri, S, Airoldi, C, Manocchio, A, Lacerenza, L, Ottini, A, Colombo, E, Nuzzolese, I, Copelli, C, Manfuso, A, Abou-Foul, A, Nankivell, P, De, M, Mehanna, H, Falcone, M, Giuliani, F, Vener, C, Miceli, R, Cristofaro, V, Resteghini, C, Singer, S, Taylor, K, Mercalli, F, Martinelli, E & Licitra, L 2026, '367 Secondary endpoint analysis of the BD4QoL randomized trial (NCT05315570): domain-specific quality of life changes in head and neck cancer survivors', Radiotherapy and Oncology, vol. 216, no. Supplement 1, pp. S98-S99. https://doi.org/10.1016/S0167-8140(26)00256-2
Mehanna, HM, Gaunt, P, Forster, M, Kong, A, Sen, M, Hartley, A, Geropantas, D, Moleron, R, Ghebretinsea, F, Gaunt, C, Humphreys, I, Nabi, Z, Garikipati, S, MacKenzie, J, Casswell, G, Aynsley, E, Ward, A, Sanghera, P, Paleri, V & Nankivell, P 2025, '1317O Results from CompARE phase III RCT: Neoadjuvant durvalumab plus chemoradiotherapy (CRT) followed by adjuvant durvalumab immunotherapy (IO) vs CRT alone in intermediate and high-risk oropharyngeal cancer (OPC)', Annals of Oncology, vol. 36, no. Supplement 2, pp. S768-S768. https://doi.org/10.1016/j.annonc.2025.08.1949
Mehanna, HM, Baliga, S, Parente, P, Chua, MLK, Porceddu, S, Simon, C, Aguilar, F, Calvo, AC, Culie, D, Giger, R, Arias, VG, Arnau, MG, Rogado, J, Sanabria, A, Stoehr, M, Zuñiga, SF, Valdivieso, J, Casadevall, D & Sanz, MT 2025, '1399P Prognostic model driven by explainable AI integrating multilingual EHR data outperforms TNM staging in locally advanced HNSCC', Annals of Oncology, vol. 36, no. Supplement 2, pp. S859-S860. https://doi.org/10.1016/j.annonc.2025.08.2031
Cavalieri, S, Airoldi, C, Manocchio, A, Lacerenza, L, Ottini, A, Nuzzolese, I, Colombo, E, Copelli, C, Manfuso, A, Abou-Foul, A, Nankivell, P, De, M, Mehanna, HM, Falcone, M, Giuliani, F, Vener, C, Miceli, R & Licitra, LFL 2025, 'LBA49 Primary endpoint analysis of the BD4QoL study, a multicenter randomized trial for monitoring quality of life by intelligent tools in head and neck cancer survivors after curative treatment', Annals of Oncology, vol. 36, no. Supplement 2, pp. S1592-S1593. https://doi.org/10.1016/j.annonc.2025.09.061
Review article
Kacker, S, Najjar, W, Stemme, R, Samaha, NL, Yenokyan, G, Armache, M, Hearn, M, Dorris, CS, Todsen, T, De Almeida, J, Fagan, J, Mehanna, H, Fakhry, C, Gharzai, LA, Gupta, S, Ettman, CK & Mady, LJ 2026, 'Assessing Financial Toxicity in Cancer: A Global Systematic Review and Meta‐Analysis Using an Asset Framework', Cancer Medicine, vol. 15, no. 7, e72082. https://doi.org/10.1002/cam4.72082
Cavalieri, S, De Cecco, L, Monzani, D, Mehanna, H, Ferrarotto, R, Simon, C, Haddad, R, Saintigny, P, Le Tourneau, C & Licitra, L 2026, 'Integrating transcriptomic data and artificial intelligence to personalize curative treatments for head and neck cancer patients', npj Precision Oncology, vol. 10, no. 1, 170. https://doi.org/10.1038/s41698-026-01369-2
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