Dr Pip Nicolson MA MB BChir (Cantab) PhD MRCP FRCPath

Dr Pip Nicolson

Institute of Cardiovascular Sciences
Affiliated with Institute of Cancer and Genomic Sciences
Clinical Lecturer in Haematology
Specialty Registrar in Clinical Haematology

Contact details

Address
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Pip is clinical academic with a clinical interest in non-malignant haematology and a research interest in the role of platelets in venous thrombosis and thromboinflammation.

He works in the Birmingham Platelet Group and in the department of Haematology at the Queen Elizabeth Hospital, Birmingham. He chairs the UK-wide, registrar-led research network HaemSTAR and was awarded the BSH-NIHR Researcher of the year award in 2019 for his work with this group. He is a drummer and keen cyclist, regularly participating in domestic and international sportives and century rides.

Qualifications

  • Fellowship of the Royal College of Pathologists, 2020
  • PhD, University of Birmingham, 2019
  • Membership of the Royal College of Physicians (UK) 2011
  • MA (Natural Sciences), University of Cambridge, 2009
  • MB BChir, University of Cambridge, 2008
  • BA (Natural Sciences), University of Cambridge, 2005

Teaching

  • Dental Sciences (Non-malignant haematology)
  • Medical Sciences (Cardiovascular Physiology)

Postgraduate supervision

  • Supervisor to MRes students
  • Supervisor to Intercalating medical students
  • Personal Mentor to Medical Students

Research

  • Investigating the role of platelet ITAM receptors in human venous thrombosis and thromboinflammation.
  • Changing the non-malignant haematology research landscape using mass participation clinical studies mediated via HaemSTAR

Research Groups 

Fellowship and Grant Awards 

  • BHF Accelerator Award (PI)
  • Principia Biopharma (second grant) (PI)
  • Dynamic Investment Fund Award (PI)
  • BHF Accelerator Award (PI)
  • 2019 – Principia Biopharma Research Grant (PI)
  • 2019 – MRC Proximity to Discovery Grant (PI)
  • 2018 – Novartis Pharmaceuticals Research Grant (PI)
  • 2018 - Rigel Pharmaceuticals Research grant (Sub I)
  • 2018 - SACC Katie Bolam Research Award (PI)
  • 2017 - BHF Clinical Research Training Fellowship
  • 2015 - ITM Starter Fellowship

Other activities

  • Co-Lead of the NIHR supported national registrar research collaborative HaemSTAR (HaemSTAR.org)
  • Invited Lecturer in non-malignant haematology on the MSc in Clinical Sciences Course at Keele University
  • Examiner for the European Certificate in Essential Palliative Care
  • Member of the Scientific Committee for the British Society of Haematology

Publications

Recent publications

Article

Cooper, NI, Altomare, I, Thomas, MR, Nicolson, P, Watson, S, Markovtsov, V, Todd, LK, Masuda, E & Bussel, JB 2021, 'Assessment of thrombotic risk during long-term treatment of immune thrombocytopenia with fostamatinib', Therapeutic Advances in Hematology, vol. 12, 20406207211010875. https://doi.org/10.1177/20406207211010875

Arachchillage, DRJ, Rajakurana, I, Odho, Z, Crossette-Thambiah, C, Nicolson, P, Roberts, L, Allan, C, Lewis, S, Riat, R, Mounter, P, Lynch, C, Langridge, A, Oakes, R, Aung, N, Drebes, A, Dutt, T, Raheja, P, Delaney, A, Essex, S, Lowe, G, Sutton, D, Lentaigne, C, Sayar, Z, Kilner, M, Everington, T, Shapiro, S, Alikhan, R, Szydlo, R, Makris, M & Laffan, M 2021, 'Clinical outcomes and the impact of prior oral anticoagulant use in patients with coronavirus disease 2019 admitted to hospitals in the UK — a multicentre observational study', British Journal of Haematology. https://doi.org/10.1111/bjh.17787

Nicolson, P, Nock, SH, Hinds, J, Garcia Quintanilla, L, Smith, C, Campos, J, Brill, A, Pike, J, Khan, A, Poulter, N, Kavanagh, D, Watson, S, Watson, CN, Clifford, H, Huissoon, A, Pollitt, A, Eble, JA, Pratt, D, Watson, S & Hughes, C 2021, 'Low-dose Btk inhibitors selectively block platelet activation by CLEC-2', Haematologica, vol. 106, no. 1, pp. 208-219. https://doi.org/10.3324/haematol.2019.218545

Harbi, M, Smith, C, Nicolson, P, Watson, S & Thomas, MR 2021, 'Novel antiplatelet strategies targeting GPVI, CLEC-2 and tyrosine kinases', Platelets, vol. 32, no. 1, pp. 29-41. https://doi.org/10.1080/09537104.2020.1849600

Smith, C, Kardeby, C, Di, Y, Lowe, G, Lester, W, Watson, S & Nicolson, P 2021, 'Platelet Activation by Vaccine-Induced Immune Thrombotic Thrombocytopenia (VITT) Patient Serum is Blocked by COX, P2Y12 and Kinase Inhibitors', medRxiv, vol. 2021, pp. 1-23. https://doi.org/10.1101/2021.04.24.21255655

Dutt, T, Shaw, RJ, Stubbs, M, Yong, J, Bailiff, B, Cranfield, T, Crowley, MP, Desborough, M, Eyre, TA, Gooding, R, Grainger, J, Hanley, J, Haughton, J, Hermans, J, Hill, Q, Humphrey, L, Lowe, G, Lyall, H, Mohsin, M, Nicolson, PLR, Priddee, N, Rampotas, A, Rayment, R, Rhodes, S, Taylor, A, Thomas, W, Tomkins, O, Van Veen, JJ, Lane, S, Toh, C & Scully, M 2021, 'Real-world experience with caplacizumab in the management of acute TTP', Blood, vol. 137, no. 13, pp. 1731–1740. https://doi.org/10.1182/blood.2020007599

Crossette-Thambiah, C, Nicolson, P, Rajakurana, I, Langridge, A, Sayar, Z, Perelta, MR, Essex, S, Oakes, R, Mounter, P, Lewis, S, Dutt, T, Scott, I, Aung, N, Shapiro, S, Laffan, M & Arachchillage, DRJ 2021, 'The clinical course of COVID-19 in pregnant versus non-pregnant women requiring hospitalisation: results from the multicentre UK CA-COVID-19 study', British Journal of Haematology. https://doi.org/10.1111/bjh.17579

Altohami, M, Langridge, A, Shareef, E & Nicolson, P 2021, 'The negative impact of the COVID-19 pandemic on UK haematology registrars’ wellbeing and training. Results of a UK nationwide survey', EJHaem. <http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1365-2141>

Nicolson, P, Welsh, J, Chauhan, A, Thomas, MR, Kahn, ML & Watson, S 2020, 'A rationale for blocking thromboinflammation in COVID-19 with Btk inhibitors', Platelets, vol. 31, no. 5, pp. 685-690. https://doi.org/10.1080/09537104.2020.1775189

Khan, A, Maclachlan, A, Lowe, G, Nicolson, P, Al Ghaithi, RHR, Thomas, S, Watson, S, Pike, J & Morgan, N 2020, 'High-throughput platelet spreading analysis: a tool for the diagnosis of platelet-based bleeding disorders', Haematologica, vol. 105, pp. e124-e128. https://doi.org/10.3324/haematol.2019.225912

Khan, A, Slater, A, Maclachlan, A, Nicolson, P, Pike, J, Reyat, J, Yule, J, Stapley, R, Rayes, J, Thomas, S & Morgan, N 2020, 'Post-translational polymodification of β1-tubulin regulates motor protein localisation in platelet production and function', Haematologica, vol. 2020, no. 00, pp. 1-43. https://doi.org/10.3324/haematol.2020.270793

Nicolson, P, Desborough, MJR, Hart, D, Biss, TT, Lowe, G & Toh, C-H 2019, 'A HaemSTAR is born; a trainee-led, UK-wide research network in haematology', Clinical Medicine. https://doi.org/10.7861/clinmed.2019-0313

Chapter

Haining, EJ, Nicolson, PLR, Onselaer, MB, Poulter, NS, Rayes, J, Thomas, MR & Watson, SP 2019, GPVI and CLEC-2. in Platelets. Elsevier Masson, pp. 213-226. https://doi.org/10.1016/B978-0-12-813456-6.00011-4

Letter

Smith, C, Montague, S, Kardeby, C, Di, Y, Lowe, G, Lester, W, Watson, S & Nicolson, P 2021, 'Anti-platelet drugs block platelet activation by vaccine-induced immune thrombocytopenia and thrombosis patient serum', Blood. https://doi.org/10.1182/blood.2021012277

Review article

Thomas, MR & Nicolson, P 2021, 'Inhibiting novel mechanisms of thrombosis: next-generation antiplatelet therapy', Platelets, vol. 32, no. 1, pp. 5-6. https://doi.org/10.1080/09537104.2020.1853422

View all publications in research portal

Culture and collections

Schools, institutes and departments

Services and facilities