Dr Pip Nicolson MA MB BChir (Cantab) PhD MRCP FRCPath

Dr Pip Nicolson

Institute of Cardiovascular Sciences
Affiliated with Institute of Cancer and Genomic Sciences
Clinical Lecturer in Haematology
Specialty Registrar in Clinical Haematology

Contact details

Address
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Pip is clinical academic with a clinical interest in non-malignant haematology and a research interest in the role of platelets in venous thrombosis and thromboinflammation.

He works in the Birmingham Platelet Group and in the department of Haematology at the Queen Elizabeth Hospital, Birmingham. He chairs the UK-wide, registrar-led research network HaemSTAR and was awarded the BSH-NIHR Researcher of the year award in 2019 for his work with this group. He is a drummer and keen cyclist, regularly participating in domestic and international sportives and century rides.

Qualifications

  • Fellowship of the Royal College of Pathologists, 2020
  • PhD, University of Birmingham, 2019
  • Membership of the Royal College of Physicians (UK) 2011
  • MA (Natural Sciences), University of Cambridge, 2009
  • MB BChir, University of Cambridge, 2008
  • BA (Natural Sciences), University of Cambridge, 2005

Teaching

  • Dental Sciences (Non-malignant haematology)
  • Medical Sciences (Cardiovascular Physiology)

Postgraduate supervision

  • Supervisor to MRes students
  • Supervisor to Intercalating medical students
  • Personal Mentor to Medical Students

Research

  • Investigating the role of platelet ITAM receptors in human venous thrombosis and thromboinflammation.
  • Changing the non-malignant haematology research landscape using mass participation clinical studies mediated via HaemSTAR

Research Groups 

Fellowship and Grant Awards 

  • BHF Accelerator Award (PI)
  • Principia Biopharma (second grant) (PI)
  • Dynamic Investment Fund Award (PI)
  • BHF Accelerator Award (PI)
  • 2019 – Principia Biopharma Research Grant (PI)
  • 2019 – MRC Proximity to Discovery Grant (PI)
  • 2018 – Novartis Pharmaceuticals Research Grant (PI)
  • 2018 - Rigel Pharmaceuticals Research grant (Sub I)
  • 2018 - SACC Katie Bolam Research Award (PI)
  • 2017 - BHF Clinical Research Training Fellowship
  • 2015 - ITM Starter Fellowship

Other activities

  • Co-Lead of the NIHR supported national registrar research collaborative HaemSTAR (HaemSTAR.org)
  • Invited Lecturer in non-malignant haematology on the MSc in Clinical Sciences Course at Keele University
  • Examiner for the European Certificate in Essential Palliative Care
  • Member of the Scientific Committee for the British Society of Haematology

Publications

Recent publications

Article

Kemble, S, Dalby, A, Lowe, G, Nicolson, P, Watson, S, Senis, Y, Thomas, S & Harrison, P 2022, 'Analysis of preplatelets and their barbell platelet derivatives by imaging flow cytometry', Blood Advances, vol. 6, no. 9, pp. 2932–2946. https://doi.org/10.1182/bloodadvances.2021006073

Montague, S, Smith, C, Lodwick, CS, Stoneley, C, Roberts, M, Lowe, G, Lester, W, Watson, S & Nicolson, P 2022, 'Anti-platelet factor 4 immunoglobulin G levels in vaccine-induced immune thrombocytopenia and thrombosis: persistent positivity through 7 months', Research and Practice in Thrombosis and Haemostasis, vol. 6, no. 3, e12707. https://doi.org/10.1002/rth2.12707

Harbi, M, Smith, C, Alenazy, F, Nicolson, P, Tiwari, A, Watson, S & Thomas, MR 2022, 'Antithrombotic effects of fostamatinib in combination with conventional antiplatelet drugs', International Journal of Molecular Sciences, vol. 23, no. 13, 6982. https://doi.org/10.3390/ijms23136982

CA-COVID-19 study group 2022, 'Autoimmune disease and COVID-19: a multicentre observational study in the United Kingdom', Rheumatology (Oxford, England). https://doi.org/10.1093/rheumatology/keac209

HaemSTAR Collaborators & Nicolson, P 2022, 'Diagnostic uncertainty presented barriers to the timely management of acute thrombotic thrombocytopenic purpura in the United Kingdom between 2014 and 2019', Journal of thrombosis and haemostasis : JTH. https://doi.org/10.1111/jth.15681

Booth, S, The HaemSTAR Network, Nicolson, P, Desborough, M, Curry, N & Stanworth, S 2022, 'Platelet transfusion and anticoagulation in haematological cancer-associated thrombosis and thrombocytopenia: the CAVEaT multi-centre prospective cohort', Journal of thrombosis and haemostasis : JTH. https://doi.org/10.1111/jth.15748

Cooper, NI, Ghalima, W, Hill, Q, Nicolson, P, Markovtsov, V & Kessler, C 2022, 'Recent advances in understanding spleen tyrosine kinase (SYK) in human biology and disease, with a focus on fostamatinib', Platelets, vol. 34, no. 1, 2131751. https://doi.org/10.1080/09537104.2022.2131751

Colicchia, M, Schrottmaier, WC, Perrella, G, Reyat, JS, Begum, J, Slater, A, Price, J, Clark, JC, Zhi, Z, Simpson, M, Bourne, J, Poulter, NS, Khan, AO, Nicolson, PLR, Pugh, MR, Harrison, P, Iqbal, AJ, Rainger, GE, Watson, SP, Thomas, MR, Mutch, NJ, Assinger, A & Rayes, J 2022, 'S100A8/A9 drives the formation of procoagulant platelets through GPIbα', Blood. https://doi.org/10.1182/blood.2021014966

Smith, C, Harbi, M, Garcia Quintanilla, L, Rookes, K, Brown, H, Poulter, N, Watson, S, Nicolson, P & Thomas, MR 2022, 'The Btk inhibitor AB-95-LH34 potently inhibits atherosclerotic plaque-induced thrombus formation and platelet procoagulant activity', Journal of Thrombosis and Haemostasis. https://doi.org/10.1111/jth.15899

Cooper, NI, Altomare, I, Thomas, MR, Nicolson, P, Watson, S, Markovtsov, V, Todd, LK, Masuda, E & Bussel, JB 2021, 'Assessment of thrombotic risk during long-term treatment of immune thrombocytopenia with fostamatinib', Therapeutic Advances in Hematology, vol. 12, 20406207211010875. https://doi.org/10.1177/20406207211010875

Arachchillage, DRJ, Rajakurana, I, Odho, Z, Crossette-Thambiah, C, Nicolson, P, Roberts, L, Allan, C, Lewis, S, Riat, R, Mounter, P, Lynch, C, Langridge, A, Oakes, R, Aung, N, Drebes, A, Dutt, T, Raheja, P, Delaney, A, Essex, S, Lowe, G, Sutton, D, Lentaigne, C, Sayar, Z, Kilner, M, Everington, T, Shapiro, S, Alikhan, R, Szydlo, R, Makris, M & Laffan, M 2021, 'Clinical outcomes and the impact of prior oral anticoagulant use in patients with coronavirus disease 2019 admitted to hospitals in the UK — a multicentre observational study', British Journal of Haematology. https://doi.org/10.1111/bjh.17787

Letter

Nicolson, P 2022, 'A single 1 g/kg dose of intravenous immunoglobulin is a safe and effective treatment for immune thrombocytopenia; results of the first HaemSTAR “Flash-Mob” retrospective study incorporating 961 patients', British Journal of Haematology, vol. 196, no. 2, pp. 433-437. https://doi.org/10.1111/bjh.17692

Buka, R, Roy, N & Nicolson, P 2022, 'UK media reporting of NICE recommendation of crizanlizumab for patients with sickle cell disease', EJHaem. <https://onlinelibrary.wiley.com/journal/26886146>

Smith, C, Montague, S, Kardeby, C, Di, Y, Lowe, G, Lester, W, Watson, S & Nicolson, P 2021, 'Anti-platelet drugs block platelet activation by vaccine-induced immune thrombocytopenia and thrombosis patient serum', Blood. https://doi.org/10.1182/blood.2021012277

Review article

Thomas, MR & Nicolson, P 2021, 'Inhibiting novel mechanisms of thrombosis: next-generation antiplatelet therapy', Platelets, vol. 32, no. 1, pp. 5-6. https://doi.org/10.1080/09537104.2020.1853422

View all publications in research portal

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