Recent publications
Article
Jooss, NJ, Smith, CW, Slater, A, Montague, SJ, Di, Y, O'shea, C, Thomas, MR, Henskens, YMC, Heemskerk, JWM, Watson, SP & Poulter, NS 2022, 'Anti-GPVI nanobody blocks collagen- and atherosclerotic plaque-induced GPVI clustering, signaling and thrombus formation', Journal of Thrombosis and Haemostasis, vol. 20, no. 11, pp. 2617-2631. https://doi.org/10.1111/jth.15836
Harbi, M, Smith, C, Alenazy, F, Nicolson, P, Tiwari, A, Watson, S & Thomas, MR 2022, 'Antithrombotic effects of fostamatinib in combination with conventional antiplatelet drugs', International Journal of Molecular Sciences, vol. 23, no. 13, 6982. https://doi.org/10.3390/ijms23136982
Brady, PF, Chua, W, Nehaj, F, Connolly, DL, Khashaba, A, Purmah, YJV, Ul-Qamar, MJ, Thomas, MR, Varma, C, Schnabel, RB, Zeller, T, Fabritz, L & Kirchhof, PF 2022, 'Interactions Between Atrial Fibrillation and Natriuretic Peptide in Predicting Heart Failure Hospitalization or Cardiovascular Death', Journal of the American Heart Association, vol. 11, no. 4, e022833. https://doi.org/10.1161/JAHA.121.022833
Colicchia, M, Schrottmaier, WC, Perrella, G, Reyat, JS, Begum, J, Slater, A, Price, J, Clark, JC, Zhi, Z, Simpson, M, Bourne, J, Poulter, NS, Khan, AO, Nicolson, PLR, Pugh, MR, Harrison, P, Iqbal, AJ, Rainger, GE, Watson, SP, Thomas, MR, Mutch, NJ, Assinger, A & Rayes, J 2022, 'S100A8/A9 drives the formation of procoagulant platelets through GPIbα', Blood. https://doi.org/10.1182/blood.2021014966
Smith, C, Harbi, M, Garcia Quintanilla, L, Rookes, K, Brown, H, Poulter, N, Watson, S, Nicolson, P & Thomas, MR 2022, 'The Btk inhibitor AB-95-LH34 potently inhibits atherosclerotic plaque-induced thrombus formation and platelet procoagulant activity', Journal of Thrombosis and Haemostasis. https://doi.org/10.1111/jth.15899
Cooper, NI, Altomare, I, Thomas, MR, Nicolson, P, Watson, S, Markovtsov, V, Todd, LK, Masuda, E & Bussel, JB 2021, 'Assessment of thrombotic risk during long-term treatment of immune thrombocytopenia with fostamatinib', Therapeutic Advances in Hematology, vol. 12, 20406207211010875. https://doi.org/10.1177/20406207211010875
Perrella, G, Huang, J, Provenzale, I, Swieringa, F, Heubel-Moenen, F, Farndale, RW, Roest, M, Van Der Meijden, P, Thomas, M, Ariëns, RAS, Jandrot-Perrus, M, Watson, S & Heemskerk, JWM 2021, 'Nonredundant roles of platelet glycoprotein VI and integrin αIIbβ3 in fibrin-mediated microthrombus formation', Arteriosclerosis Thrombosis and Vascular Biology, vol. 41, no. 2, pp. e97–e111. https://doi.org/10.1161/ATVBAHA.120.314641
Harbi, M, Smith, C, Nicolson, P, Watson, S & Thomas, MR 2021, 'Novel antiplatelet strategies targeting GPVI, CLEC-2 and tyrosine kinases', Platelets, vol. 32, no. 1, pp. 29-41. https://doi.org/10.1080/09537104.2020.1849600
Slater, A, Di, Y, Clark, J, Jooss, N, Martin, E, Alenazy, F, Thomas, MR, Ariëns, RAS, Herr, AB, Poulter, N, Emsley, J & Watson, S 2021, 'Structural characterisation of a novel GPVI nanobody-complex reveals a biologically active domain-swapped GPVI dimer', Blood, vol. 2021, no. 00, pp. 1-20. https://doi.org/10.1182/blood.2020009440
Nicolson, P, Welsh, J, Chauhan, A, Thomas, MR, Kahn, ML & Watson, S 2020, 'A rationale for blocking thromboinflammation in COVID-19 with Btk inhibitors', Platelets, vol. 31, no. 5, pp. 685-690. https://doi.org/10.1080/09537104.2020.1775189
Ow, KW, Parker, WAE, Porter, MM, Hanson, J, Judge, HM, Briffa, NP, Thomas, MR & Storey, RF 2020, 'Offset of ticagrelor prior to coronary artery bypass graft surgery for acute coronary syndromes: effects on platelet function and cellular adenosine uptake', Platelets, vol. 31, no. 7, pp. 945-951. https://doi.org/10.1080/09537104.2019.1709631
Ubaid, S, Ford, TJ, Berry, C, Murray, HM, Wrigley, B, Khan, N, Thomas, MR, Armesilla, AL, Townend, JN, Khogali, SS, Munir, S, Martins, J, Hothi, SS, McAlindon, EJ & Cotton, JM 2019, 'Cangrelor versus Ticagrelor in Patients Treated with Primary Percutaneous Coronary Intervention: Impact on Platelet Activity, Myocardial Microvascular Function and Infarct Size: A Randomized Controlled Trial', Thrombosis and Haemostasis, vol. 119, no. 7, pp. 1171-1181. https://doi.org/10.1055/s-0039-1688789
Chua, WL, Purmah, Y, Roth Cardoso, V, Gkoutos, G, Tull, S, Neculau, G, Thomas, MR, Kotecha, D, Lip, G, Kirchhof, P & Fabritz, L 2019, 'Data-driven discovery and validation of circulating blood-based biomarkers associated with prevalent atrial fibrillation.', European Heart Journal, vol. 40, no. 16, pp. 1268-1276. https://doi.org/10.1093/eurheartj/ehy815
Editorial
Harrison, P, Lordkipanidzé, M, Andrew L. Frelinger, III, Thomas, MR & Watson, SP 2020, 'Platelet count and disease – editorial policy', Platelets, vol. 31, no. 8, pp. 969-970. https://doi.org/10.1080/09537104.2020.1802002
Review article
Thomas, MR & Nicolson, P 2021, 'Inhibiting novel mechanisms of thrombosis: next-generation antiplatelet therapy', Platelets, vol. 32, no. 1, pp. 5-6. https://doi.org/10.1080/09537104.2020.1853422
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