Dr Christopher Green MBBS BMedSci(Hons) DTM&H MRCP(UK) DPhil(Oxon)

Dr Chris Green

School of Chemical Engineering
Associate Clinical Professor & Consultant Physician in Infectious Diseases

Contact details

School of Chemical Engineering
University of Birmingham
B15 2TT

Christopher Green is a clinical academic specialising in Infectious Diseases. He has contributed to over 150 peer-reviewed scientific papers and has special interests in experimental vaccine development (UK), vaccine impact (Africa) and global health research.


  • Certificate of Completion of Training (CCT) in Infectious Diseases and General (Internal) Medicine 2018
  • Doctor of Philosophy (DPhil), University of Oxford 2017
  • Member of the Royal College of Physicians (MRCP), Royal College of Physicians 2010
  • Diploma in Tropical Medicine & Hygiene (DTMH), Royal College of Physicians 2008
  • Bachelor of Medicine and Bachelor of Surgery (MBBS), University of Newcastle upon Tyne 2004
  • Bachelor of Medical Science (BMedSci) with 2: honours in Visual Neuroscience, University of Newcastle upon Tyne 2002


Christopher Green works as both a practicing physician in the NHS and an academic researcher with the University.

His NHS work takes him to the front line of acute care and speciality medicine work that focusses on the diagnosis and management of complex infection. During his clinical training in Infectious Diseases he was fortunate enough to be seconded to the University of Oxford to further develop his interests in vaccinology and global health. There he worked on the accelerated evaluation of novel vaccine candidates for enteric fever using a controlled human challenge model of infection and lead several phase 1 (first-in-human) clinical trials of new vaccine technologies against other infectious diseases.

The focus of his DPhil was in leading the world’s first clinical trials of viral-vectored vaccine technology for respiratory syncytial virus (RSV). This work was directedly relevant for the urgent research needed to develop new drugs and vaccines to safely control the COVID-19 pandemic a few years later.

He worked as the principal investigator for a large portfolio of urgent public health research at the same time as his clinical role in this period, which included membership of the SAGE group of scientists and work on hospital disease epidemiology and modelling.

His ongoing research interests include the development of new and novel vaccines through early-stage human trials, understanding the host immune response to infection/vaccination, and in preparing low- to middle-income countries (LMICs) to have the ‘next generation’ vaccine cold-chain systems needed to deploy new vaccine technologies and to mitigate the complex effects from climate change.


Research areas

  • Experimental vaccine research – special interest in early-phase clinical trials and controlled human-challenge studies
  • Applied vaccine research – special interest in vaccine deployment and impact in African/LMIC settings
  • Translational clinical research
  • Applied computer science – special interest in artificial intelligence for antimicrobial resistance

Other activities

Principal Investigator for clinical trials of investigational medicinal products (CTIMPs) at the NIHR/Wellcome Clinical Research Facility at University Hospitals Birmingham NHS Foundation Trust; early-stage vaccine candidates and use of controlled human challenge models for accelerated vaccine evaluation.

Consultant Physician in Infectious Diseases and General (internal) Medicine, Dept of Infectious Diseases & Tropical Medicine, University Hospitals Birmingham NHS Foundation Trust.

Co-Chair of the national NIHR Infectious Diseases Vaccine Research Forum (UKID-VRF).

Programme Director for Health at the Africa Centre for Excellence in Sustainable Cooling and Cold-chain (ACES).

Clinical Research Specialty Lead for Infection& Immunology for NIHR West Midlands Regional Research Delivery Network.

Faculty member of the UK Clinical Vaccine Network (UKCVN).

Member of the data safety monitoring committee (DMSC) for several early-phase vaccine CTIMPs.

Key recent posts

  • Member of the COVID Clinical Information Network member (Clinical Characterisation of Covid-19 admitted to hospitals in the UK committee) subgroup of the Scientific Advisory Group of Emergencies (SAGE) (2020-2023)
  • NIHR Academy – Lead for Infection (2019-2023)
  • Member of the ISARIC 4C consortium (2020-2023)
  • Member of the NIHR task and finish group on aerosol generating procedures for COVID-19 (2020-2021)


Over 150 peer-reviewed, original research papers and other contributions; list available at Google Scholar.

These include original research papers as main author contribution in high-impact journals such as NEJM (one paper), Lancet (12 papers), JAMA (one paper), BMJ (2 papers), Lancet Respiratory Medicine (3 papers), Lancet Infectious Diseases (one paper), Lancet Diabetes and Endocrinology (one paper), Journal of Infection (5 papers) and many others.