Professor Iain Chapple PhD, BDS, FDSRCPS, FDSRCS, CCST (Rest Dent)

Iain Chapple

School of Dentistry
Professor of Periodontology and Consultant in Restorative Dentistry
Head of Research for Institute of Clinical Sciences

Contact details

The School of Dentistry
5 Mill Pool Way
B5 7EG
United Kingdom

Iain Chapple was Head of the School of Dentistry between 2016-2020 and he continues to be Head of Research for the Institute of Clinical Sciences. He is also Professor and Head of Periodontology within the School, and Honorary Consultant in Restorative Dentistry with Birmingham Community Health Trust. He has honorary consultant contracts with University Hospital Birmingham Foundation Trust and Birmingham Children’s Hospital Trust.

Iain has published over 220 research papers in the peer reviewed scientific literature, and written and edited 9 textbooks and authored 23 book chapters in the field of Periodontology, Periodontal Medicine and Surgery, Nutrition and Molecular Methods. Iain has received major grants from the Medical Research Council, European Union, Charities and Industry. 

Iain is a committed an enthusiastic teacher of undergraduate and postgraduate students within Birmingham and internationally on various graduate programs across Europe, North America and the Asia-Pacific rim.

Iain is former Scientific Editor of the British Dental Journal, former Associate Editor of Journal of Periodontal Research, current Associate Editor of the Journal of Clinical Periodontology and Periodontology 2000. 

Iain was awarded the Charles Tomes medal of the Royal College of Surgeons of England in 2012; the Distinguished Scientist Award of the International Association for Dental Research (Periodontal Research) in 2018; and the Special Citation Award of the American Academy of Periodontology in 2018.

Iain was President of the International Association for Dental Research (IADR) Periodontal Research Group (PRG-2006-7), Treasurer (2007-2013) and Secretary General (2016-2019) of the European Federation of Periodontology (EFP) and is currently Treasurer of the UK Oral and Dental Research Trust. He co-chairs the EFP workshops (research and education).

Iain is clinical lead for a hospital regional specialist periodontal service (referral base of 6-million) and a national oral care service for adult Epidermolysis Bullosa patients.


  • Honorary fellow of the Royal College of Surgeons of Edinburgh (Dental Surgery) 2004.
  • Certificate of completion of specialist training (Rest Dent) – joint Royal Colleges 1996.
  • PhD (University of Birmingham) – 1993.
  • Fellow of the Royal College of Physicians and Surgeons of Glasgow (Dental Surgery) 1989.
  • Bachelor of Dental Surgery (Newcastle) 1986.


  • BDS
  • BSc in Dental Hygiene and Therapy
  • MSc Advanced General Dental Practice
  • International programs (doctoral programs in Europe and USA – visiting Professor)

Postgraduate supervision

Iain Chapple has research and doctoral supervision interests in the fields of periodontology, periodontal medicine and surgery, nutrition and molecular methods. He has received major grants from the Medical Research Council, the European Union and industry. Professor Chapple leads the periodontal research group, whose interests include:

Innate immunity in the pathobiology of periodontitis
Diagnostic biomarkers for periodontitis and associated systemic diseases
Periodontal inflammation and systemic inflammatory conditions
Periodontitis and immunesenescence
Micronutritional modulation of inflammation
Clinical trials in periodontal therapy

Professor Chapple also established the clinical trials team at Birmingham, which runs clinical studies on disease pathogenesis as well as diagnosis and therapy to international GCP standards. He welcomes applications from potential doctoral researchers in his areas of interest.

Other activities

  • Secretary General of European Federation of Periodontology.
  • Treasurer of UK Oral and Dental Research Trust.
  • Specialist advisor to Department of Health in Periodontology.
  • Board member of the European Nutraceutical Association.
  • Associate Editor of Journal of Clinical Periodontology.
  • Editorial Board member of Periodontology 2000.
  • Executive Committee member of European federation of Periodontology.
  • Global Expert Panel – Unilever Oral Care Research.
  • Expert advisor for Philips Oral Healthcare.
  • Expert advisor for Johnson & Johnson.
  • Consultant to – spin out company of The University of Birmingham.
  • Executive Board member of European Nutraceutical Association.


Recent publications


Ademowo, OS, Sharma, P, Cockwell, P, Reis, A, Chapple, I, Griffiths, HR & Dias, IHK 2020, 'Distribution of plasma oxidised phosphatidylcholines in chronic kidney disease and periodontitis as a co-morbidity', Free Radical Biology and Medicine, vol. 146, pp. 130-138.

Rapson, A, Collman, E, Faustini, S, Yonel, Z, Chapple, I, Drayson, M, Richter, A, Campbell, JP & Heaney, J 2020, 'Free light chains as an emerging biomarker in saliva: biological variability and comparisons with salivary IgA and steroid hormones', Brain, Behaviour, and Immunity, vol. 83, pp. 78-86.

Sanz, M, Chapple, I & Dietrich, T 2020, 'Periodontitis and cardiovascular diseases: consensus report', Journal of Clinical Periodontology, vol. 47, no. 3, pp. 268–288.

Sapey, E, Yonel, Z, Edgar, R, Parmar, S, Hobbins, S, Crossley, D, Usher, A, Johnson, S, Walton, G, McGuinness, A, Chapple, I & Stockley, R 2020, 'The clinical and inflammatory relationships between periodontitis and chronic obstructive pulmonary disease', Journal of Clinical Periodontology.

Yonel, Z, Batt, J, Jane, R, Cerullo, E, Gray, LJ, Dietrich, T & Chapple, I 2020, 'The role of the oral healthcare team in identification of type 2 diabetes mellitus: a systematic review.', Current Oral Health Reports.

Serban, S, Dietrich, T, Lopez-Oliva, I, De Pablo, P, Raza, K, Filer, A, Chapple, I & Hill, K 2019, 'Attitudes towards oral health in patients with rheumatoid arthritis: a qualitative study nested within a randomized controlled trial', JDR Clinical & Translational Research, vol. 4, no. 4, pp. 360-370.

Giannobile, WV, Berglundh, T, Al-nawas, B, Araujo, M, Bartold, PM, Bouchard, P, Chapple, I, Gruber, R, Lundberg, P, Sculean, A, Lang, NP, Lyngstadaas, P, Kebschull, M, Galindo-moreno, P, Schwartz, Z, Shapira, L, Stavropoulos, A & Reseland, J 2019, 'Biological factors involved in alveolar bone regeneration: consensus report of Working Group 1 of the 15th European Workshop on Periodontology on Bone Regeneration ', Journal of Clinical Periodontology, vol. 46, no. S21, pp. 6-11.

Lopez-Oliva, I, De Pablo, P, Dietrich, T & Chapple, I 2019, 'Gums and joints: is there a connection? Part one: epidemiological and clinical links', British Dental Journal, vol. 227, pp. 605–609.

Lopez-Oliva, I, De Pablo, P, Dietrich, T & Chapple, I 2019, 'Gums and joints: is there a connection? Part two: the biological link', British Dental Journal, vol. 227, pp. 611–617.

Levy, DH, Chapple, ILC, Shapira, L, Golan-goldhirsh, A, Gopas, J & Polak, D 2019, 'Nupharidine enhances aggregatibacter actinomycetemcomitans clearance by priming neutrophils and augmenting their effector functions', Journal of Clinical Periodontology, vol. 46, no. 1, pp. 62-71.

Moonen, CG, Hirschfeld, J, Cheng, L, Chapple, I, Loos, BG & Nicu, EA 2019, 'Oral neutrophils characterized: chemotactic, phagocytic, and Neutrophil Extracellular Trap (NET) formation properties', Frontiers in immunology, vol. 10, 635.


Grant, M & Chapple, I Oct. 17 2019, DIAGNOSTICS OF MILD OR ADVANCED PERIODONTITIS, Patent No. WO2019197449, IPC No. G01N 33/68 . <>

Grant, M & Chapple, I Oct. 17 2019, GINGIVITIS DIAGNOSTIC METHODS, USES AND KITS, Patent No. WO2019197451, IPC No. G01N 33/68. <>


Review article

McBain, AJ & Chapple, I 2019, 'Consumer safety considerations of skin and oral microbiome perturbation', Clinical Microbiology Reviews, vol. 32, no. 4, e00051-19.

View all publications in research portal


Periodontal Diseases