Professor Iain Chapple PhD, BDS, FDSRCPS, FDSRCS, CCST (Rest Dent)

Iain Chapple

School of Dentistry
Head of the School of Dentistry
Professor of Periodontology and Consultant in Restorative Dentistry

Contact details

The School of Dentistry
5 Mill Pool Way
B5 7EG
United Kingdom

Iain Chapple is Head of the School of Dentistry within the Institute of Clinical Sciences. Iain is also Professor and Head of Periodontology within the School, and Honorary Consultant in Restorative Dentistry with Birmingham Community Health Trust. Iain has honorary consultant contracts with University Hospital Birmingham Foundation Trust and Birmingham Children’s Trust. Iain is former Designated Individual for the Human Tissue Authority in Dentistry at Birmingham.

Iain has published over 250 research papers and abstracts in scientific journals, and written and edited 7 textbooks and authored 16 book chapters in the field of Periodontology, Periodontal Medicine and Surgery, Nutrition and Molecular Methods. Iain has received major grants from the Medical Research Council, European Union and Industry. 

Iain is a committed an enthusiastic teacher of undergraduate and postgraduate students within Birmingham and also internationally on various graduate programs across Europe, North America and Asia-Pacific rim.

Iain is former Scientific Editor of the British Dental Journal, former Associate Editor of Journal of Periodontal Research, current Associate Editor of the Journal of Clinical Periodontology and Periodontology 2000. 

Iain was elected President of the International Association for Dental Research (IADR) Periodontal Research Group (PRG-2006-7), was Treasurer of the European Federation of Periodontology (EFP – 2007-2013) and is currently Secretary General of the EFP and Treasurer of the UK Oral and Dental Research Trust. He co-chairs the EFP workshops (research and education).

Iain is clinical lead for a hospital regional specialist periodontal service (referral base >6-million) and a national oral care service for adult Epidermolysis Bullosa patients.

Iain was awarded the Charles Tomes medal of the Royal College of Surgeons of England in 2012. 


  • Honorary fellow of the Royal College of Surgeons of Edinburgh (Dental Surgery) 2004.
  • Certificate of completion of specialist training (Rest Dent) – joint Royal Colleges 1996.
  • PhD (University of Birmingham) – 1993.
  • Fellow of the Royal College of Physicians and Surgeons of Glasgow (Dental Surgery) 1989.
  • Bachelor of Dental Surgery (Newcastle) 1986.


  • BDS
  • BSc in Dental Hygiene and Therapy
  • MSc Advanced General Dental Practice
  • International programs (doctoral programs in Europe and USA – visiting Professor)

Postgraduate supervision

Iain Chapple has research and doctoral supervision interests in the fields of periodontology, periodontal medicine and surgery, nutrition and molecular methods. He has received major grants from the Medical Research Council, the European Union and industry. Professor Chapple leads the periodontal research group, whose interests include:

Innate immunity in the pathobiology of periodontitis
Diagnostic biomarkers for periodontitis and associated systemic diseases
Periodontal inflammation and systemic inflammatory conditions
Periodontitis and immunesenescence
Micronutritional modulation of inflammation
Clinical trials in periodontal therapy

Professor Chapple also established the clinical trials team at Birmingham, which runs clinical studies on disease pathogenesis as well as diagnosis and therapy to international GCP standards. He welcomes applications from potential doctoral researchers in his areas of interest.

Other activities

  • Secretary General of European Federation of Periodontology.
  • Treasurer of UK Oral and Dental Research Trust.
  • Specialist advisor to Department of Health in Periodontology.
  • Board member of the European Nutraceutical Association.
  • Associate Editor of Journal of Clinical Periodontology.
  • Editorial Board member of Periodontology 2000.
  • Executive Committee member of European federation of Periodontology.
  • Global Expert Panel – Unilever Oral Care Research.
  • Expert advisor for Philips Oral Healthcare.
  • Expert advisor for Johnson & Johnson.
  • Consultant to – spin out company of The University of Birmingham.
  • Executive Board member of European Nutraceutical Association.


Recent publications


Giannobile, WV, Berglundh, T, Al-nawas, B, Araujo, M, Bartold, PM, Bouchard, P, Chapple, I, Gruber, R, Lundberg, P, Sculean, A, Lang, NP, Lyngstadaas, P, Kebschull, M, Galindo-moreno, P, Schwartz, Z, Shapira, L, Stavropoulos, A & Reseland, J 2019, 'Biological factors involved in alveolar bone regeneration: consensus report of Working Group 1 of the 15th European Workshop on Periodontology on Bone Regeneration ' Journal of Clinical Periodontology, vol. 46, no. S21, pp. 6-11.

Moonen, CG, Hirschfeld, J, Cheng, L, Chapple, I, Loos, BG & Nicu, EA 2019, 'Oral neutrophils characterized: chemotactic, phagocytic, and Neutrophil Extracellular Trap (NET) formation properties' Frontiers in immunology, vol. 10, 635.

Serban, S, Dietrich, T, Lopez-Oliva, I, De Pablo, P, Raza, K, Filer, A, Chapple, I & Hill, K 2019, 'Attitudes towards oral health in patients with rheumatoid arthritis: a qualitative study nested within a randomized controlled trial' JDR Clinical & Translational Research.

Walter, C, Ower, P, Tank, M, West, NX, Needleman, I, Hughes, FJ, Wadia, R, Milward, MR, Hodge, PJ, Chapple, ILC & Dietrich, T 2019, 'Periodontal diagnosis in the context of the 2017 classification system of periodontal diseases and conditions: Presentation of a middle-aged patient with localised periodontitis' British Dental Journal, vol. 226, no. 2, pp. 98-100.

British Society of Periodontology, Dietrich, T, Ower, P, Tank, M, West, NX, Walter, C, Needleman, I, Hughes, FJ, Wadia, R, Milward, MR, Hodge, PJ & Chapple, ILC 2019, 'Periodontal diagnosis in the context of the 2017 classification system of periodontal diseases and conditions - implementation in clinical practice' British Dental Journal, vol. 226, no. 1, pp. 16-22.

British Society of Periodontology 2019, 'Periodontal diagnosis in the context of the BSP implementation plan for the 2017 classification system of periodontal diseases and conditions: presentation of a pair of young siblings with periodontitis' British Dental Journal, vol. 226, no. 1, pp. 23-26.

Sharma, P, Yonel, Z, Chapple, I & Dietrich, T 2018, 'Association between periodontal health status and patient-reported outcomes in patients managed in a non-specialist, general dental practice' Journal of Clinical Periodontology.

Yonel, Z, Sharma, P, Yahyouche, A, Jalal, Z, Dietrich, T & Chapple, I 2018, 'Patients’ attendance patterns to different healthcare settings and perceptions of stakeholders regarding screening for chronic, non-communicable diseases in high street dental practices and community pharmacy: a cross- sectional study' BMJ open, vol. 8, no. 11, e024503.

Levy, DH, Chapple, ILC, Shapira, L, Golan-goldhirsh, A, Gopas, J & Polak, D 2018, 'Nupharidine enhances aggregatibacter actinomycetemcomitans clearance by priming neutrophils and augmenting their effector functions' Journal of Clinical Periodontology.

Seren, S, Rashed Abouzaid, M, Eulenberg-Gustavus, C, Hirschfeld, J, Nasr Soliman, H, Jerke, U, N'Guessan, K, Dallet-Choisy, S, Lesner, A, Lauritzen, C, Schacher, B, Eickholz, P, Nagy, N, Szell, M, Croix, C, Viaud-Massuard, M-C, Al Farraj Aldosari, A, Ragunatha, S, Ibrahim Mostafa, M, Giampieri, F, Battino, M, Cornillier, H, Lorette, G, Stephan, J-L, Goizet, C, Pedersen, J, Gauthier, F, Jenne, DE, Marchand-Adam, S, Chapple, IL, Kettritz, R & Korkmaz, B 2018, 'Consequences of cathepsin C inactivation on membrane expression of proteinase 3, the target antigen in autoimmune vasculitis' Journal of Biological Chemistry, vol. 293, no. 32, pp. 12415-12428.

Lopez-Oliva, I, Paropkari, AD, Saraswat, S, Serban, S, Yonel, Z, Sharma, P, de Pablo, P, Raza, K, Filer, A, Chapple, I, Dietrich, T, Grant, MM & Kumar, PS 2018, 'Dysbiotic subgingival microbial communities in periodontally healthy patients with rheumatoid arthritis' Arthritis and Rheumatology.

G. Caton, J, Chapple, ILC, Armitage, G, Berglundh, T, Jepsen, S, S. Kornman, K, L. Mealey, B, Papapanou, PN, Sanz, M & S. Tonetti, M 2018, 'A new classification scheme for periodontal and peri-implant diseases and conditions - Introduction and key changes from the 1999 classification' Journal of Periodontology, vol. 89, no. S1, pp. S1-S8.

Chapple, ILC, Mealey, BL, Van Dyke, TE, Bartold, PM, Dommisch, H, Eickholz, P, Geisinger, ML, Genco, RJ, Glogauer, M, Goldstein, M, Griffin, TJ, Holmstrup, P, Johnson, GK, Kapila, Y, Lang, NP, Meyle, J, Murakami, S, Plemons, J, Romito, GA, Shapira, L, Tatakis, DN, Teughels, W, Trombelli, L, Walter, C, Wimmer, G, Xenoudi, P & Yoshie, H 2018, 'Periodontal health and gingival diseases and conditions on an intact and a reduced periodontium: Consensus report of workgroup 1 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions' Journal of Clinical Periodontology, vol. 45, no. S20, pp. S68-S77.

Busby, M, Chapple, L, Clover, H, McCreanor, J & Chapple, I 2018, 'Capitation care fee banding and the reliability of an on-line tool' British Dental Journal.

Review article

Chapple, I 2019, 'Consumer safety considerations of skin and oral 2 microbiome perturbation' Clinical Microbiology Reviews.

View all publications in research portal


Periodontal Diseases