Highlight publications
Hewitt, BJ, Garcia Bonilla, M, McAllister II, JP, Pahuja, S, Pellowe, GA, Newman, M, Roberts, L, Roberts, JA, Kitchen, P, Bill, RM, Hill, LJ & Botfield, HF 2026 'Cross-omics profiling reveals cortical neuronal dysfunction following neonatal intraventricular haemorrhage that is attenuated by decorin treatment' bioRxiv. https://doi.org/10.64898/2026.09.07.749813
Hewitt, BJ, Roberts, L, Roberts, JA, Fulton, D, Hill, LJ, Kitchen, P, Bill, RM & Botfield, HF 2026, 'Adult organotypic brain slice cultures recapitulate extracellular matrix remodeling in hemorrhagic stroke', Frontiers in Cellular Neuroscience, vol. 19, 1722240. https://doi.org/10.3389/fncel.2025.1722240
Hewitt, BJ, Ali, M, Hubbard, J, Hill, LJ & Botfield, H 2025, 'A Systematic Review of the Differential Effects of TGF-β1 in Ischemic and Hemorrhagic Preclinical Stroke Models', Journal of the American Heart Association, vol. 14, no. 14, e037890. https://doi.org/10.1161/JAHA.124.037890
Hewitt, BJ, Batt, J, Shelton, R, Cooper, P, Landini, G, Lucas, R, Wiench, M & Milward, M 2022, 'A 3D printed device for in vitro generation of stratified epithelia at the air-liquid interface', Tissue Engineering Part C Methods, vol. 28, no. 11, pp. 599-609. https://doi.org/10.1089/ten.TEC.2022.0130
Recent publications
Article
Roberts, JA, Batie, M, Ponsford, AH, Poh, J, Hewitt, BJ, Botfield, HF, Hill, LJ, Sanderson, CM, Rocha, S & Sharma, P 2026, 'NRF2 upregulation by CDDO-Me protects AC16 human cardiomyocytes against doxorubicin-induced toxicity', Biomedicine and Pharmacotherapy, vol. 194, 118878. https://doi.org/10.1016/j.biopha.2025.118878
Odyniec, ML, Bell, DJ, Gallant, BM, Firdaus, R, Ball, G, Hughes, L, Oxtoby, R, Hewitt, BJ, Williams, CM, Muguruza, AR, Overton, TW, Tsai, H-J, Chiu, Y-L, Kubicki, DJ, Walmsley, AD, Kuehne, SA & Pikramenou, Z 2026, 'Ultrasound-Responsive Nanoparticles Enable Hydrophobic Antibiotic Release and Deep Penetration for Biofilm Treatment', JACS Au, vol. 6, no. 3, pp. 1847–1859. https://doi.org/10.1021/jacsau.5c01711
Solera Sales, L, Hewitt, B, Muchová, M, Lourenção Brighenti, F, Kuehne, SA, Grant, MM & Milward, MR 2025, 'Anti-inflammatory, antioxidant, and antimicrobial evaluation of morin', Archives of Oral Biology, vol. 178, 106343. https://doi.org/10.1016/j.archoralbio.2025.106343
Balacco, D, Hewitt, BJ, Bardhan, A, Shriane, LM, Hunjan, M, Hickerson, R, Heagerty, AHM & Chapple, IL 2025, 'Unlocking the potential: m6A-RNA methylation in severe Epidermolysis Bullosa Simplex', Bioscience Reports, vol. 45, BSR20253141. https://doi.org/10.1042/BSR20253141
Abstract
Balacco, DL, Hewitt, B, Bardhan, A, Khanna, D, Shriane, LM, Hunjan, M, Hickerson, R, Heagerty, A & Chapple, I 2025, '0538 Exploring the role of m6A-RNA methylation in severe epidermolysis bullosa simplex', Journal of Investigative Dermatology, vol. 145, no. 8, pp. S93-S93. https://doi.org/10.1016/j.jid.2025.06.545
Hewitt, B & Botfield, H 2025, 'An in vitro model of post-haemorrhagic hydrocephalus', Brain and Neuroscience Advances, vol. 9, 23982128251339055, pp. 2-3. https://doi.org/10.1177/23982128251339055
Roberts, L, Hewitt, BJ, Kitchen, P, Bill, R & Botfield, H 2025, 'Distribution and localisation of the water channel, AQP4, in organotypic brain slice cultures', Brain and Neuroscience Advances, vol. 9, 23982128251339055, pp. 2-2. https://doi.org/10.1177/23982128251339055
Doctoral Thesis
Hewitt, BJ 2025, 'The effect of nuclear hormone receptor stimulation in oral epithelia', ???thesis.qualification.phd???, The University of Birmingham. <http://etheses.bham.ac.uk//id/eprint/14866/>
Preprint
Hewitt, BJ, Roberts, L, Roberts, JA, Fulton, D, Hill, L, Kitchen, P, Bill, RM & Botfield, H 2025 'Adult organotypic brain slice cultures recapitulate extracellular matrix remodelling in haemorrhagic stroke' bioRxiv. https://doi.org/10.1101/2025.07.15.665021
Roberts, JA, Batie, M, Ponsford, AH, Poh, J, Hewitt, BJ, Botfield, HF, Hill, LJ, Sanderson, CM, Rocha, S & Sharma, P 2025 'NRF2 upregulation by CDDO-Me protects AC16 human cardiomyocytes against doxorubicin-induced toxicity.' bioRxiv. https://doi.org/10.1101/2025.09.10.675420
Hewitt, BJ, Ali, M, Hubbard, J, Hill, LJ & Botfield, H 2024 'The double-edged sword of transforming growth factor β 1: a systematic review of pre-clinical stroke models' Research Square. https://doi.org/10.21203/rs.3.rs-4687466/v1
Pelepenko, LE, Hewitt, B, Janini, ACP, Moraes, BF, Pereira, JS, Leutz, ACN & Marciano, MA 2023 'Protocol for subcutaneous implantation of polyethylene tubes containing endodontic reparative materials in 12-week-old Wistar rats' Protocol Exchange. https://doi.org/10.21203/rs.3.pex-2482/v1
Review article
Pelepenko, LE, Hewitt, B, Bueno de Oliveira, R, Fornazaro Moraes, B, C. Coraça-Huber, D, Janini, ACP & Angélica Marciano, M 2025, 'Bismuth release from endodontic materials: proposed mechanisms for systemic circulation and organ accumulation', Journal of Hazardous Materials, vol. 494, 138580. https://doi.org/10.1016/j.jhazmat.2025.138580
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