Recent publications
Article
Cumberland, M, Euchner, J, Azad, A, Vo, NTN, Kirchhof, P, Holmes, A, Denning, C & Gehmlich, K 2024, 'Generation of a human iPSC-derived cardiomyocyte/fibroblast engineered heart tissue model [version 1; peer review: 1 approved, 2 approved with reservations]', F1000Research, vol. 12, 1224. https://doi.org/10.12688/f1000research.139482.1
Sommerfeld, LC, Holmes, AP, Yu, TY, O'Shea, C, Kavanagh, DM, Pike, JM, Wright, T, Syeda, F, Aljehani, A, Kew, T, Cardoso, VR, Kabir, SN, Hepburn, C, Menon, PR, Broadway‐Stringer, S, O'Reilly, M, Witten, A, Fortmueller, L, Lutz, S, Kulle, A, Gkoutos, GV, Pavlovic, D, Arlt, W, Lavery, GG, Steeds, R, Gehmlich, K, Stoll, M, Kirchhof, P & Fabritz, L 2024, 'Reduced plakoglobin increases the risk of sodium current defects and atrial conduction abnormalities in response to androgenic anabolic steroid abuse', The Journal of Physiology. https://doi.org/10.1113/jp284597
Holmes, AP & Kumar, P 2023, 'Low sugar and the drive to breathe: Is insulin another adequate stimulus for the carotid body?', Experimental Physiology, vol. 108, no. 2, pp. 167-168. https://doi.org/10.1113/EP091008
Cumberland, M, Riebel, LL, Roy, A, O'Shea, C, Holmes, A, Denning, C, Kirchhof, P, Rodriguez, B & Gehmlich, K 2022, 'Basic Research Approaches to Evaluate Cardiac Arrhythmia in Heart Failure and Beyond', Frontiers in Physiology, vol. 13, 806366. https://doi.org/10.3389/fphys.2022.806366
Al-Maswary, AA, O'Reilly, M, Holmes, AP, Walmsley, AD, Cooper, PR & Scheven, BA 2022, 'Exploring the neurogenic differentiation of human dental pulp stem cells', PLoS ONE, vol. 17, no. 11, e0277134. https://doi.org/10.1371/journal.pone.0277134
O'Reilly, M, Sommerfeld, LC, O'Shea, C, Broadway-Stringer, S, Andaleeb, S, Reyat, JS, Kabir, SN, Stastny, D, Malinova, A, Delbue, D, Fortmueller, L, Gehmlich, K, Pavlovic, D, Skryabin, BV, Holmes, AP, Kirchhof, P & Fabritz, L 2022, 'Familial atrial fibrillation mutation M1875T-SCN5A increases early sodium current and dampens the effect of flecainide', EP Europace. https://doi.org/10.1093/europace/euac218
O’Shea, C, Winter, J, Kabir, SN, O’Reilly, M, Wells, SP, Baines, O, Sommerfeld, LC, Correia, J, Lei, M, Kirchhof, P, Holmes, AP, Fabritz, L, Rajpoot, K & Pavlovic, D 2022, 'High resolution optical mapping of cardiac electrophysiology in pre-clinical models', Scientific Data, vol. 9, no. 1, 135. https://doi.org/10.1038/s41597-022-01253-1
O'Brien, S-M, Holmes, A, Johnson, D, Kabir, SN, O'Shea, C, O'Reilly, M, Avezzu, A, Reyat, J, Hall, AW, Apicella, C, Ellinor, PT, Niederer, S, Tucker, NR, Fabritz, L, Kirchhof, P & Pavlovic, D 2022, 'Increased atrial effectiveness of flecainide conferred by altered biophysical properties of sodium channels', Journal of Molecular and Cellular Cardiology, vol. 166, pp. 23-35. https://doi.org/10.1016/j.yjmcc.2022.01.009
MacMillan, S, Holmes, AP, Dallas, ML, Mahmoud, AD, Shipston, MJ, Peers, C, Hardie, DG, Kumar, P & Evans, AM 2022, 'LKB1 is the gatekeeper of carotid body chemosensing and the hypoxic ventilatory response', Communications Biology, vol. 5, no. 1, 642. https://doi.org/10.1038/s42003-022-03583-7
Comment/debate
MacMillan, S, Holmes, AP, Dallas, ML, Mahmoud, AD, Shipston, MJ, Peers, C, Hardie, DG, Kumar, P & Evans, AM 2022, 'Publisher correction: LKB1 is the gatekeeper of carotid body chemosensing and the hypoxic ventilatory response (Communications biology (2022) 5 1 (642))', Communications Biology, vol. 5, no. 1, 765. https://doi.org/10.1038/s42003-022-03744-8
Conference contribution
Aldossary, HS, Nieves, DJ, Kavanagh, DM, Owen, D, Ray, CJ, Kumar, P, Coney, AM & Holmes, AP 2023, Analyzing Angiotensin II Receptor Type 1 Clustering in PC12 Cells in Response to Hypoxia Using Direct Stochastic Optical Reconstruction Microscopy (dSTORM). in SV Conde, R Iturriaga, R del Rio, E Gauda & EC Monteiro (eds), Arterial Chemoreceptors: Mal(adaptive) Responses: O2 Dependent and Independent Mechanisms. 1 edn, Advances in Experimental Medicine and Biology, vol. 1427, Springer, pp. 175-184, ISAC XXI 2022, Lisbon, Portugal, 27/06/22. https://doi.org/10.1007/978-3-031-32371-3_19
Review article
Sha, R, Baines, O, Hayes, A, Tompkins, K, Kalla, M, Holmes, AP, O'Shea, C & Pavlovic, D 2024, 'Impact of Obesity on Atrial Fibrillation Pathogenesis and Treatment Options', Journal of the American Heart Association, vol. 13, no. 1, e032277. https://doi.org/10.1161/JAHA.123.032277
Baines, O, Sha, R, Kalla, M, Holmes, AP, Efimov, IR, Pavlovic, D & O’Shea, C 2024, 'Optical mapping and optogenetics in cardiac electrophysiology research and therapy: a state-of-the-art review', Europace, vol. 26, no. 2, euae017, pp. 1-14. https://doi.org/10.1093/europace/euae017
Saleeb-Mousa, J, Nathanael, D, Coney, AM, Kalla, M, Brain, KL & Holmes, AP 2023, 'Mechanisms of Atrial Fibrillation in Obstructive Sleep Apnoea', Cells, vol. 12, no. 12, 1661. https://doi.org/10.3390/cells12121661
Holmes, AP, Swiderska, A, Nathanael, D, Aldossary, HS, Ray, CJ, Coney, AM & Kumar, P 2022, 'Are multiple mitochondrial related signalling pathways involved in carotid body oxygen sensing?', Frontiers in Physiology, vol. 13, 908617. https://doi.org/10.3389/fphys.2022.908617
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