Dr Farhat Latif Khanim PhD

More of Dr Khanim's other activities:

• Ecancer.org features a video of Dr Khanim interviewed by ecancer tv at the 2016 BACR and ECMC Joint Meeting
• Dr Khanim spoke at the Drug Repurposing for Rare Diseases Conference in 2017 and a copy of her slides can be found at findacure
• The video below shows Dr Farhat Khanim describing how the Circles of Influence campaign is aiding her translational research into Burkitt's Lymphoma amongst children in Africa.

 

Recent publications

Article

Sheard, JJ, Southam, AD, MacKay, HL, Ellington, MA, Snow, MD, Khanim, FL, Bunce, CM & Johnson, WE 2021, 'Combined bezafibrate, medroxyprogesterone acetate and valproic acid treatment inhibits osteosarcoma cell growth without adversely affecting normal mesenchymal stem cells', Bioscience Reports, vol. 41, no. 1, BSR20202505. https://doi.org/10.1042/BSR20202505

Lima, MA, Skidmore, M, Khanim, F & Richardson, A 2021, 'Development of a nano-luciferase based assay to measure the binding of SARS-CoV-2 spike receptor binding domain to ACE-2', Biochemical and Biophysical Research Communications, vol. 534, pp. 485-490. https://doi.org/10.1016/j.bbrc.2020.11.055

Eraslan, Z, Papatzikas, G, Cazier, J-B, Khanim, FL & Günther, UL 2021, 'Targeting Asparagine and Serine Metabolism in Germinal Centre-Derived B Cells Non-Hodgkin Lymphomas (B-NHL)', Cells, vol. 10, no. 10, pp. 2589. https://doi.org/10.3390/cells10102589

Davies, SP, Mycroft-West, CJ, Pagani, I, Hill, HJ, Chen, Y-H, Karlsson, R, Bagdonaite, I, Guimond, SE, Stamataki, Z, De Lima, MA, Turnbull, JE, Yang, Z, Vicenzi, E, Skidmore, MA, Khanim, FL & Richardson, A 2021, 'The Hyperlipidaemic Drug Fenofibrate Significantly Reduces Infection by SARS-CoV-2 in Cell Culture Models', Frontiers in Pharmacology, vol. 12, pp. 660490. https://doi.org/10.3389/fphar.2021.660490

Gleneadie, HJ, Baker, AH, Batis, N, Bryant, J, Jiang, Y, Clokie, SJH, Mehanna, H, Garcia, P, Gendoo, DMA, Roberts, S, Burley, M, Molinolo, AA, Gutkind, JS, Scheven, BA, Cooper, PR, Parish, JL, Khanim, FL & Wiench, M 2021, 'The anti-tumour activity of DNA methylation inhibitor 5-aza-2′-deoxycytidine is enhanced by the common analgesic paracetamol through induction of oxidative stress', Cancer Letters, vol. 501, pp. 172-186. https://doi.org/10.1016/j.canlet.2020.12.029

Jiang, Y, Southam, AD, Trova, S, Beke, F, Alhazmi, B, Francis, T, Radotra, A, Di Maio, A, Drayson, MT, Bunce, CM & Khanim, FL 2021, 'Valproic acid disables the Nrf2 anti-oxidant response in acute myeloid leukaemia cells enhancing reactive oxygen species-mediated killing', British Journal of Cancer, vol. 126, no. 2, pp. 275-286. https://doi.org/10.1038/s41416-021-01570-z

Bryant, J, Batis, N, Franke, AC, Clancey, G, Hartley, M, Ryan, G, Brooks, J, Southam, AD, Barnes, N, Parish, J, Roberts, S, Khanim, F, Spruce, R & Mehanna, H 2019, 'Repurposed quinacrine synergizes with cisplatin, reducing the effective dose required for treatment of head and neck squamous cell carcinoma', OncoTarget, vol. 10, no. 50, pp. 5229-5244. https://doi.org/10.18632/oncotarget.27156

Abdullah, MI, Abed, MN, Khanim, F & Richardson, A 2019, 'Screening a library of approved drugs reveals that prednisolone synergizes with pitavastatin to induce ovarian cancer cell death', Scientific Reports, vol. 9, no. 1, 9632. https://doi.org/10.1038/s41598-019-46102-1

Drayson, M, Murray, J, Pratt, G, Jacob, A, Clark, F, Blundred, R, Fox, S, Bishop, R, Wheatley, K, Khanim, F & Bunce, C 2019, 'Single arm phase II trial assessing the safety, compliance with and activity of bezafibrate and medroxyProgesterone acetate (BaP) therapy against myeloid and lymphoid cancers', Contemporary Clinical Trials Communications, vol. 14, 100361. https://doi.org/10.1016/j.conctc.2019.100361

Barini, E, Miccoli, A, Tinarelli, F, Mulholland, K, Kadri, H, Khanim, F, Stojanovski, L, Read, KD, Burness, K, Blow, JJ, Mehellou, Y & Muqit, MMK 2018, 'The Anthelmintic Drug Niclosamide and Its Analogues Activate the Parkinson's Disease Associated Protein Kinase PINK1', ChemBioChem, vol. 19, no. 5, pp. 425-429. https://doi.org/10.1002/cbic.201700500

Denbigh, JL, Perez-Guaita, D, Vernooij, RR, Tobin, MJ, Bambery, KR, Xu, Y, Southam, AD, Khanim, FL, Drayson, MT, Lockyer, NP, Goodacre, R & Wood, BR 2017, 'Probing the action of a novel anti-leukaemic drug therapy at the single cell level using modern vibrational spectroscopy techniques', Scientific Reports, vol. 7, 2649. https://doi.org/10.1038/s41598-017-02069-5

Calamita, P, Miluzio, A, Russo, A, Pesce, E, Ricciardi, S, Khanim, F, Cheroni, C, Alfieri, R, Mancino, M, Gorrini, C, Rossetti, G, Peluso, I, Pagani, M, Medina, DL, Rommens, J & Biffo, S 2017, 'SBDS-Deficient Cells Have an Altered Homeostatic Equilibrium due to Translational Inefficiency Which Explains their Reduced Fitness and Provides a Logical Framework for Intervention', PLoS Genetics, vol. 13, no. 1, e1006552. https://doi.org/10.1371/journal.pgen.1006552

Clarke, K, Ricciardi, S, Pearson, T, Bharudin, I, Davidsen, PK, Bonomo, M, Brina, D, Scagliola, A, Simpson, DM, Beynon, RJ, Khanim, F, Ankers, J, Sarzynski, MA, Ghosh, S, Pisconti, A, Rozman, J, Hrabe de Angelis, M, Bunce, C, Stewart, C, Egginton, S, Caddick, M, Jackson, M, Bouchard, C, Biffo, S & Falciani, F 2017, 'The Role of Eif6 in Skeletal Muscle Homeostasis Revealed by Endurance Training Co-expression Networks', Cell Reports, vol. 21, no. 6, pp. 1507-1520. https://doi.org/10.1016/j.celrep.2017.10.040

Comment/debate

Bryan, RT, Arnold, R, Khanim, FL, Shepherd, DE, Patel, P & Ward, DG 2021, 'Establishing the Bladder Cancer Research Centre at the University of Birmingham', Nature Reviews Urology, vol. 18, no. 6, pp. 318-320. https://doi.org/10.1038/s41585-021-00448-2

Review article

Bunce, CM & Khanim, FL 2018, 'The 'known-knowns', and 'known-unknowns' of extracellular Nm23-H1/NDPK proteins', Laboratory investigation. https://doi.org/10.1038/s41374-017-0012-5

View all publications in research portal