Lieutenant Colonel Professor James Mitchell BSc MB BS MRCP PhD RAMC

Lieutenant Colonel Professor James Mitchell

Department of Biomedical Sciences
Consultant Neurologist and Rehabilitation Physician
Honorary Clinical Professor in Neurology

Contact details

Address
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Lt Col Professor James Mitchell is a Military Clinician Scientist and Consultant in Neurology and Rehabilitation at University Hospitals Birmingham and Defence Medical Rehabilitation Centre, and an Honorary Clinical Professor in Neurology at the University of Birmingham. Lt Col Professor Mitchell is a member of the leadership team for the Translational Brain Science Research Group and Chief Investigator of the mTBI-Predict consortium and UK MEGaBlast study. 

He has a strong interest in the mechanisms, impact and treatment of traumatic brain injury, with a dual speciality in neurology and rehabilitation. He leads both the UK Military TBI Service and associated research, and integrates military and civilian brain injury pathways, embedding research into clinical practice and enabling rapid translation to improve care.  

Qualifications

  • PhD, University of Birmingham (2022)
  • MBBS, Imperial College School of Medicine (2007)
  • BSc, Imperial College School of Medicine, (2005)

Biography

James is a Military Clinician Scientist (Ministry of Defence/University of Birmingham) and Consultant in Neurology and Rehabilitation (University Hospitals Birmingham - UHB/Defence Medical Rehabilitation Centre), internationally recognised for his expertise in neurotrauma. He leads the UK Military Traumatic Brain Injury (TBI) Service and is Chief Investigator of the mTBI Predict Consortium; a prospective, multi-centre study focused on improving diagnosis and management of mild TBI with research integrating clinical data, biomarkers, and advanced imaging to predict long-term outcomes to enhance the care for both military personnel and civilians. James also leads the UK MEGaBlast study, which aims to develop a mobile Magnetoencephalography (MEG) platform to understand the impact of blast exposure on brain health; this research combines exposure measurements, cognitive performance testing, blood biomarkers, and detailed MEG brain scanning to better understand the neurological effects in key military service personnel.

James completed his medical training in at Imperial College London, intercalating in neuroscience. Following foundation training at the Royal Centre for Defence Medicine (UHB), he undertook Officer Training at the Royal Military Academy Sandhurst and served as a Regimental Medical Officer, earning membership of the Royal College of Physicians at this time. During a formative operational tour in Afghanistan (2011-12), he delivered primary, pre-hospital, and in-hospital trauma care. On his return, James completed Core Medical Training (West Midlands Deanery) before specialising in neurology and rehabilitation and become a consultant in 2023.

His research career began with an NIHR Academic Clinical Fellowship, and in 2016 he secured MoD PhD funding to lead the IIH Pressure Trial, which demonstrated the effectiveness of GLP-1 receptor agonists in treating Idiopathic Intracranial Hypertension (IIH), also playing a leading role in the IIH Drug and IIH Weight trials. From 2019 he was a founding member of the mTBI Predict Consortium, gaining funding through the MoD and DoD to open and sustain the consortium, he assumed leadership of the consortium in early 2025.

Research

Research interests

  • Magnetoencephalography (MEG) for neurological diagnosis
  • Understanding the effect of blast exposure on brain functionality
  • Biomarkers for mild traumatic brain injury
  • Intracranial pressure and neuroprotection following traumatic brain injury

Related research

For additional information on research and publications please visit James' Research Gate Profile.

Other activities

Awards

  • North American Neuro-Ophthalmological Society - Best abstract by a resident (2022)
  • American Space Medicine Association - Ross McFarland Student/Resident award - Best research abstract (2022)
  • International Headache Congress - First prize - Best clinical paper award (2021)