Dr Animesh Acharjee PhD, PGCE, FHEA

Dr Animesh Acharjee

Department of Cancer and Genomic Sciences
Associate Professor
Deputy Programme Director, MSc in Health Data Science (Dubai)
EDI Lead, Department of Cancer and Genomic Sciences

Contact details

Address
Department of Cancer and Genomic Sciences
University of Birmingham
Edgbaston
Birmingham
B15 2TT

Animesh Acharjee is an Associate Professor of Integrative Analytics and AI (Health Data Science) and Deputy Programme Director, MSc in Health Data Science (Dubai) in the Department of Cancer and Genomic Sciences. 

Please see Integrative analytics and AI team website for detail information.

Qualifications

  • Postgraduate Certificate in Education (PGCE), Distinction, University of Birmingham, UK, 2025
  • PhD in Omics data analysis, Wageningen University, The Netherlands
  • MSc in Bioinformatics, IBAB, Bangalore, India
  • BTech in Electrical Engineering, NERIST, India

Biography

Dr. Acharjee did his undergraduate degree in Electrical Engineering from North Eastern Regional Institute of Technology (NERIST), Itanagar, India and Masters in Bioinformatics from Institute of Bioinformatics and Applied Biotechnology, Bangalore , India. After his Masters, he earned his PhD from Wageningen University, The Netherlands, on applied machine learning and data analysis. After his PhD he moved to Lyon, France, for his post-doctoral study with Synergie Lyon Cancer Centre as a Biostatistician where he extensively worked on big data analytics, cloud computing. After his post-doctoral study he was offered a scientist position with BASF Cropdesign, Belgium.

Before joining University of Birmingham and Queen Elizabeth Hospital he was working with University of Cambridge, Cambridge, UK focusing on metabolic driven diseases like Obesity, T2-diabetis using high throughput metabolomics, lipidomics technologies. His research interests includes integrative data analytics, predictive biomarker discovery, bioinformatics methods for diagnostics and network biology. Throughout his career, he was offered many fellowships from British Council, Dutch Government and Newton fellowships. He has published many papers in the international journals and actively collaborate with many Universities, for example Harvard University and University of Cambridge. So far, he has published 83 papers, and his h index is 25 based on google scholar.

Teaching

  • Integrative Multimodal Data Analytics
  • Health Data Fundamentals
  • MRes - Cancer Science
  • Genome Medicine
  • Clinical Bioinformatics
  • Foundation Year-2 (FY-2)

Research

1. Integrative analytics

Dr. Acharjee applies novel approaches to the diverse multi omics data e.g. genetics, transcriptomics, proteomics, metabolomics, single cell transcriptomics to integrate them and identify novel therapeutic mechanisms and/or disease mechanisms. The data sets used in those studies are often public (ex: TCGA, GEO etc) or stakeholders’ experimental data. To perform an integration, Dr. Acharjee often uses machine learning/AI methods derived from multiple experiments across many diseases. Some of the examples of integration are here: microbiome and inflammatory markers in infant cohort (Wood and Acharjee et al., Allergy, 2021); microbiome, metabolome and single cell sequence data in the colon cancer cohort (Bisht et al.,  Int J Mol Sci. 2021; Quraishi and Acharjee et al., J Crohns Colitis, 2020) and multiple metabolomics data sets integration (Acharjee et al., BMC Bioinformatics, 2016).

2. Diagnostics

Unlike previous portfolio, this aspect considers single omics or clinical data including variety of machine learning methods. Some examples include identification of the markers from cytokine profiling data (Bravo-Merodio and Acharjee et al., Sci Data. 2019), diagnostic marker from miRNA  (Di Pietro et al, Br J Sports Med. 2021);  metabolomics biomarker identification (Ament et al., Transl Stroke Res., 2021; Acharjee et al., Metabolomics, 2018).

3. Data analytics methods and workflow development

Dr. Acharjee is also interested to develop new bioinformatics tools /workflows that can be useful for the clinician or biologist. Some of the examples are: Microbiome analysis workflow (Bisht and Acharjee et al., Comput Biol Med, 2021), statistical power calculations online tool (Acharjee et al., BMC Medical Genomics, 2020), automatic feature selection form high dimensional omics data sets (Bravo-Merodio et al.,  J Transl Med. 2019).

Publications

Recent publications

Article

Acharjee, A & Santos, D 2026, 'Agentic artificial intelligence in inflammatory bowel disease: toward autonomous and adaptive care', Crohns & Colitis 360, vol. 8, no. 3, otag066. https://doi.org/10.1093/crocol/otag066

Dhami, J, Radhakrishnan, SK, Russ, D, Mondal, S, Alzarooni, A, Bravo Merodio, L, Duggal, NA, Gupta, R & Acharjee, A 2026, 'A Network-Based Association of IBD and Colorectal Cancer Using Proteomics Data', PROTEOMICS-Clinical Applications, vol. 20, no. 2, e70041. https://doi.org/10.1002/prca.70041

Frerichs, NM, de Kroon, RR, van Schajik, Y, el Manouni el Hassani, S, van Wesemael, AJ, de Boode, WP, Cossey, V, Hulzebos, CV, van den Akker, CHP, Raets, MMA, d’Haens, EJ, Vijlbrief, D, van Weissenbruch, MM, de Jonge, WJ, de Boer, NK, van Goudoever, JB, Beggs, AD, Quraishi, MN, Davids, M, Mondal, S, Acharjee, A, Niemarkt, HJ & de Meij, TGJ 2026, 'Early risk stratification of late-onset sepsis in very preterm infants by intestinal microbiota profiling: a multicenter case–control validation study', Gut Microbes, vol. 18, no. 1, 2693365. https://doi.org/10.1080/19490976.2026.2693365

Quinn, LM, Elliott, J, Papanikolaou, T, Litchfield, I, Boardman, F, Boiko, O, Randell, M, Zakia, F, Garstang, J, Shukla, D, Burt, C, Gkoutos, G, Acharjee, A, Dayan, C, Faustini, S, Bentley, C, Barrett, T, Richter, A, Greenfield, SM, Dias, RP & Narendran, P 2026, 'Feasibility of general population screening for type 1 diabetes in the UK: the ELSA study', The lancet. Diabetes & endocrinology, vol. 14, no. 3, pp. 197-199. https://doi.org/10.1016/S2213-8587(25)00363-8

Philip, D, Santos , D, Mondal, S, Alomar, H, Gkoutos, G & Acharjee, A 2026, 'Generative AI-augmented transcriptomic and microbiome analysis across inflammatory and fibrotic disease states in Crohn’s disease', Frontiers in Artificial Intelligence, vol. 9, 1881820. https://doi.org/10.3389/frai.2026.1881820

Wenning, AS, Bräutigam, K, Aeschbacher, P, Acharjee, A, Gloor, B, Perren, A & Karamitopoulou, E 2026, 'RNF43-mutations Are Associated With the Classical Molecular Subtype, Vigorous Antitumor Immune Responses and Prolonged Survival in Pancreatic Adenocarcinoma', Modern Pathology, vol. 39, no. 7, 101010. https://doi.org/10.1016/j.modpat.2026.101010

Nath, D, Ditchfield, C, Price, J, Sivakumar, S, Jones, SW & Acharjee, A 2026, 'Linking Targeted Pancreatic Cancer Genes With Metabolic Disorders: A Cross-Species Translational Pathway', Cancer Medicine, vol. 15, no. 4, e71775. https://doi.org/10.1002/cam4.71775

Horner, E, McGee, KC, Tullie, S, Naumann, DN, Acharjee, A, Lissillour, T, Asiri, A, Ng, JMS, Sullivan, J, Sardeli, AV, Harrison, P, Belli, A, Moiemen, NS, Lord, JM & Hazeldine, J 2026, 'Major Traumatic and Severe Thermal Injuries Lead to Immediate and Persistent Elevations in Circulating Concentrations of Resistin That Are Associated with Poor Clinical Outcomes and Impaired Innate Immune Responses', Biomolecules, vol. 16, no. 3, 443. https://doi.org/10.3390/biom16030443

Wilson, D, Acharjee, A, Duggal, NA, Hombrebueno, JR, Jones, SW, Lewis, JW, de Magalhães, JP, Martinez-Serrato, Y, Mazaheri, A, McGettrick, HM, Mondal, S, Naylor, AJ, Nixon, A, Nicholson, T, Partridge, J, Pinkney, T, Rattray, NJW, Steves, C, Tomkova, K, Welch, C & Jackson, T 2026, 'REPROGRAM: REsilience PROmotion with GeRoprotectors: AssessMent of biological effect: Rationale and protocol for a trial of biological effect', PLOS One, vol. 21, no. 6, e0346347. https://doi.org/10.1371/journal.pone.0346347

Sadhukhan, P & Acharjee, A 2026, 'T-SMmOTE: Tweaked Synthetic Majority minority Oversampling Technique for data scarcity issue in multi omics studies', Bioinformatics Advances. https://doi.org/10.1093/bioadv/vbag236

Opperman, RCM, van Liere, ELSA, Acharjee, A, Mondal, S, Struys, EA, Antoniadis, A, de Boer, JEB, Siriram, SR, Bakkali, A, Bosch, S, Jacobs, MAJM, Koornstra, JJ, Kuijvenhoven, JP, van Leerdam, ME, Spaander, MCW, de Meij, TGJ, Dekker, E, Ramsoekh, D & de Boer, NKH 2026, 'Urinary and Faecal Amino-Acids as Biomarkers for Colorectal Neoplasia in Lynch Syndrome—A Prospective Longitudinal Study', International Journal of Cancer. https://doi.org/10.1002/ijc.70715

Takahashi, K, Lubiatowska, M, Shehwana, H, Ruffle, JK, Williams , JA, Acharjee, A, Terai, S, Gkoutos, GV, Satti, H & Aziz, Q 2025, 'An exploratory machine learning study on paediatric abdominal pain phenotyping and prediction', PLOS One, vol. 20, no. 11, e0336215. https://doi.org/10.1371/journal.pone.0336215

Letter

Griffith, L, Sinha, A & Acharjee, A 2025, 'Alterations in Tryptophan Metabolism and the Indole Pathway in Colorectal Cancer Patients: A Systematic Review and Meta-analysis', MedComm, vol. 6, no. 12, e70466. https://doi.org/10.1002/mco2.70466

Review article

Ponsero, AJ, Bahcivanci , B, Hayhoe, A, Acharjee, A & Özkurt, E 2026, 'The human gut microbiome across the life course', FEBS Letters. https://doi.org/10.1002/1873-3468.70361

Farhat, J, Alzyoud, L, AlWahsh, M, Acharjee, A & Al-Omari, B 2025, 'Advancing Precision Medicine: The Role of Genetic Testing and Sequencing Technologies in Identifying Biological Markers for Rare Cancers', Cancer Medicine, vol. 14, no. 8, e70853. https://doi.org/10.1002/cam4.70853

View all publications in research portal