Recent publications
Article
Sheriff, L & Bending, D 2022, 'Flow cytometric analysis of CD4+ T cell re-activation following anti-PD1 immunotherapy in a transgenic mouse model', STAR Protocols, vol. 3, no. 1, 101161. https://doi.org/10.1016/j.xpro.2022.101161
Elliot, T, Jennings, E, Lecky, D, Thawait, N, Flores-Langarica, A, Copland, A, Maslowski, K, Wraith, D & Bending, D 2021, 'Antigen and checkpoint receptor engagement recalibrates T cell receptor signal strength', Immunity, vol. 54, no. 11, pp. 2481-2496.e6. https://doi.org/10.1016/j.immuni.2021.08.020
Jennings, E, Lecky, D, Ono, M & Bending, D 2021, 'Application of dual Nr4a1-GFP Nr4a3-Tocky reporter mice to study T cell receptor signaling by flow cytometry', STAR Protocols, vol. 2, no. 1, 100284. https://doi.org/10.1016/j.xpro.2020.100284
Jennings, E, Elliot, T, Thawait, N, Kanabar, S, Yam-Puc, JC, Ono, M, Toellner, K-M, Wraith, DC, Anderson, G & Bending, D 2020, 'Nr4a1 and Nr4a3 reporter mice are differentially sensitive to T cell receptor signal strength and duration', Cell Reports, vol. 33, no. 5, 108328. https://doi.org/10.1016/j.celrep.2020.108328, https://doi.org/10.1016/j.celrep.2020.108328
Bending, D, Prieto Martin, P, Paduraru, A, Ducker, C, Marzaganov, E, Laviron, M, Kitano, S, Miyachi, H, Crompton, T & Ono, M 2018, 'A Timer for analyzing temporally dynamic changes in transcription during differentiation in vivo', Journal of Cell Biology, vol. 217, no. 8, pp. 2931-2950. https://doi.org/10.1083/jcb.201711048
Bending, D, Paduraru, A, Ducker, C, Prieto Martin, P, Crompton, T & Ono, M 2018, 'A temporally dynamic Foxp3 autoregulatory transcriptional circuit controls the effector Treg programme', The EMBO journal, vol. 37, no. 16, e99013. https://doi.org/10.15252/embj.201899013
Rosser, E, Lom, H, Bending, D, Duurland, C, Bajaj-Elliott, M & Wedderburn, LR 2018, 'Brief report: Innate lymphoid cells and T-cells contribute to the IL-17A signature detected in the synovial fluid of patients with Juvenile Idiopathic Arthritis', Arthritis and Rheumatology. https://doi.org/10.1002/art.40731
Bending, D & Ono, M 2017, 'Interplay between the skin barrier and immune cells in patients with atopic dermatitis unraveled by means of mathematical modeling', Journal of Allergy and Clinical Immunology, vol. 139, no. 6, pp. 1790-1792. https://doi.org/10.1016/j.jaci.2017.03.015
Bending, D, Giannakopoulou, E, Lom, H & Wedderburn, LR 2015, 'Synovial Regulatory T Cells Occupy a Discrete TCR Niche in Human Arthritis and Require Local Signals To Stabilize FOXP3 Protein Expression', Journal of Immunology, vol. 195, no. 12, pp. 5616-5624. https://doi.org/10.4049/jimmunol.1500391
Bending, D, Pesenacker, AM, Ursu, S, Wu, Q, Lom, H, Thirugnanabalan, B & Wedderburn, LR 2014, 'Hypomethylation at the regulatory T cell-specific demethylated region in CD25hi T cells is decoupled from FOXP3 expression at the inflamed site in childhood arthritis', Journal of Immunology, vol. 193, no. 6, pp. 2699-2708. https://doi.org/10.4049/jimmunol.1400599
Piper, C, Pesenacker, AM, Bending, D, Thirugnanabalan, B, Varsani, H, Wedderburn, LR & Nistala, K 2014, 'T cell expression of granulocyte-macrophage colony-stimulating factor in juvenile arthritis is contingent upon Th17 plasticity', Arthritis & Rheumatology (Hoboken), vol. 66, no. 7, pp. 1955-1960. https://doi.org/10.1002/art.38647
Comment/debate
Bending, D & Ono, M 2017, 'FoxP3 partners up', Nature Immunology, vol. 18, no. 11, pp. 1181-1183. https://doi.org/10.1038/ni.3852
Review article
Copland, A & Bending, D 2018, 'Foxp3 molecular dynamics in Treg in juvenile idiopathic arthritis', Frontiers in immunology, vol. 9, 2273. https://doi.org/10.3389/fimmu.2018.02273
Bending, D & Ono, M 2018, 'From stability to dynamics: understanding molecular mechanisms of regulatory T cells through Foxp3 transcriptional dynamics', Clinical & Experimental Immunology. https://doi.org/10.1111/cei.13194
Working paper
Elliot, TAE, Jennings, EK, Lecky, DAJ, Thawait, N, Flores-Langarica, A, Wraith, DC & Bending, D 2021 'Antigen and checkpoint receptor recalibration of T cell receptor signal strength' bioRxiv, pp. 1-48. https://doi.org/10.1101/2021.03.02.431957
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