Professor Subrata Ghosh MD, FRCP, FRCPE, FRCPC, FCAHS

Subrata Ghosh

Institute of Immunology and Immunotherapy
Professor of Translational Medicine
Director of the Institute of Translational Medicine

Contact details

Address
Institute of Translational Medicine
College of Medical and Dental Sciences
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Professor Ghosh's interest and vision is to enable and synergise scientific discoveries into rapid translation to bedside of patients for their benefit. He is especially interested in immune mediated inflammatory diseases such as Crohn’s disease and Ulcerative colitis.

Qualifications

  • F.R.C.P.C, Royal College of Physicians and Surgeons of Canada, 2009
  • F.R.C.P.(London), Royal College of Physicians of London, 2002
  • F.R.C.P.(Edinburgh), Royal College of Physicians of Edinburgh, 1997
  • Doctorate of Medicine (Research), in Gastroenterology, University of Edinburgh, 1996
  • ECFMG (steps 1 & 2), 1991
  • MRCP (London), Royal College of Physicians of London, 1988
  • Diplomate National Board, National Board of Examinations, India, 1987
  • MD (Internal Medicine), University of Calcutta, India (postgraduate degree in internal Medicine), 1986
  • Bachelor of Medicine & Surgery (MBBS), University of Calcutta, India, 1982

Biography

Subrata Ghosh is the Director of the Institute of Translational Medicine and Professor of Translational Medicine, University of Birmingham. He took up this position on the 1st of June 2016. He moved from Canada where he was the Professor of Medicine at University of Calgary. He was cross-appointed as Professor of Immunology and microbiology and was an adjunct Professor in the department of veterinary medicine. He was the Head of the Department of Medicine at Cumming School of Medicine, University of Calgary and the Zone Clinical Department Head, Calgary Zone, Alberta Health Services. Previously, he was the Chair of Gastroenterology and Professor of Gastroenterology at the Imperial College London, Hammersmith Hospital and associate professor of gastroenterology at University of Edinburgh. Professor Ghosh is a Fellow of the Canadian Academy of Health Sciences and a member of the International Organization for the Study of IBD. He is a past editor in chief of the Canadian Journal of Gastroenterology and Hepatology, editor in chief of World Journal of Gastroenterology and associate editor of Gut, and sits on the editorial boards of several journals. He served on the Scientific Advisory Committee of the Crohn’s and Colitis Canada and Chaired its of Advocacy Committee and he was the chairman of the medical advisors of the Crohn’s and Colitis UK. Prof Ghosh has published over 470 manuscripts (h index 87). He has delivered over 600 international lectures. His research interests are focused on translational immunology of inflammatory bowel disease and novel therapeutic approaches.

Postgraduate supervision

Subrata has supervised over 20 PhD students and his laboratory is open. He is currently supervising or co-supervising 4 PhD students.

If you are interested in studying with Subrata, please contact him on the contact details above, or for any general doctoral research enquiries, please email: dr@contacts.bham.ac.uk or call +44 (0)121 414 5005.

For a full list of available Doctoral Research opportunities, please visit our Doctoral Research programme listings.

Research

My research interests span aetiopathology of IBD, immune disorders in IBD, Biomarkers in IBD, Treatment of IBD. A major focus is on dendritic cell and T cell interactions in IBD and targeting these interactions by pharmacological targeted therapies as well as by nutrient modulation.

Other activities

  • Nominated member International Organization for Study of IBD
  • Fellow of the Canadian Association of Health Sciences
  • Crohn’s and Colitis Canada –member of the scientific advisory board
  • Crohn’s and Colitis Canada – chairman of the advocacy committee
  • Crohn’s and Colitis UK- chairman of the medical advisors group

Publications

Recent publications

Article

Zhang, Z, Taylor, L, Shommu, N, Ghosh, S, Reimer, R, Panaccione, R, Kaur, S, Hyun, JE, Cai, C, Deehan, EC, Hotte, N, Madsen, KL & Raman, M 2020, 'A diversified dietary pattern is associated with a balanced gut microbial composition of Faecalibacterium and Escherichia/Shigella in patients with Crohn's disease in remission', Journal of Crohn's & Colitis. https://doi.org/10.1093/ecco-jcc/jjaa084

Smith, S, Bazarova, A, Ejenavi , E, Qurashi, M, Shivaji, U, Harvey , PR, Slaney, E, McFarlane, M, Baker, G, Elnagar, M, Yuzari , S, Gkoutos, GV, Ghosh, S & Iacucci, M 2020, 'A multicentre development and validation study of a novel Lower Gastrointestinal Bleeding score-The Birmingham Score', International journal of colorectal disease, vol. 35, pp. 285–293. https://doi.org/10.1007/s00384-019-03459-z

Quraishi, MN, Acharjee, A, Beggs, AD, Horniblow, R, Tselepis, C, Gkoutos, G, Ghosh, S, Rossiter, A, Loman, N, van Schaik, W, Withers, D, Walters, JRF, Hirschfield, GM & Iqbal, TH 2020, 'A pilot integrative analysis of colonic gene expression, gut microbiota and immune infiltration in primary sclerosing cholangitis-inflammatory bowel disease: association of disease with bile acid pathways', Journal of Crohn's & Colitis, vol. 14, no. 7, pp. 935-947. https://doi.org/10.1093/ecco-jcc/jjaa021

Iacucci, M, Ghosh, S, Cannatelli, R, Gui, XS, Bazarova, A, Zardo , D, Gkoutos, G, Lethebe, BC, Kaplan, GG, Panaccione, R, Kiesslich, R & Ghosh, S 2020, 'Assessment of endoscopic healing by using advanced technologies reflects histologic healing in ulcerative colitis', Journal of Crohn's & Colitis. https://doi.org/10.1093/ecco-jcc/jjaa056

Tan, N-D, Qiu, Y, Xing, X-B, Ghosh, S, Chen, M-H & Mao, R 2020, 'Associations between angiotensin converting enzyme inhibitors and angiotensin II receptor blocker use, gastrointestinal symptoms, and mortality among patients with COVID-19', Gastroenterology. https://doi.org/10.1053/j.gastro.2020.05.034

Kennedy, NA, Jones, G-R, Lamb, CA, Appleby, R, Arnott, I, Beattie, RM, Bloom, S, Brooks, AJ, Cooney, R, Dart, RJ, Edwards, C, Fraser, A, Gaya, DR, Ghosh, S, Greveson, K, Hansen, R, Hart, A, Hawthorne, AB, Hayee, BH, Limdi, JK, Murray, CD, Parkes, GC, Parkes, M, Patel, K, Pollok, RC, Powell, N, Probert, CS, Raine, T, Sebastian, S, Selinger, C, Smith, PJ, Stansfield, C, Younge, L, Lindsay, JO, Irving, PM & Lees, CW 2020, 'British Society of Gastroenterology guidance for management of inflammatory bowel disease during the COVID-19 pandemic', Gut, vol. 69, no. 6, pp. 984-990. https://doi.org/10.1136/gutjnl-2020-321244

Sandborn, WJ, Feagan, BG, Loftus, EV, Peyrin-biroulet, L, Van Assche, G, D’haens, G, Schreiber, S, Colombel, J, Lewis, JD, Ghosh, S, Armuzzi, A, Scherl, E, Herfarth, H, Vitale, L, Mohamed, MF, Othman, AA, Zhou, Q, Huang, B, Thakkar, RB, Pangan, AL, Lacerda, AP & Panes, J 2020, 'Efficacy and safety of upadacitinib in a randomized trial of patients with Crohn’s disease', Gastroenterology. https://doi.org/10.1053/j.gastro.2020.01.047

Sandborn , WJ, Ghosh, S, Panes, J, Schreiber, S, D'Haens, G, Tanida, S, Siffledeen, J, Enejosa, J, Zhou, W, Ahmed, O, Huang, B & Higgins, PDR 2020, 'Efficacy of upadacitinib in a randomized trial of patients with active ulcerative colitis', Gastroenterology. https://doi.org/10.1053/j.gastro.2020.02.030

Hanauer, SB, Sandborn, WJ, Feagan, BG, Gasink, C, Jacobstein, D, Zou, B, Johanns, J, Adedokun, OJ, Sands, BE, Rutgeerts, P, de Villiers, WJS, Colombel, J-F & Ghosh, S 2020, 'IM-UNITI: Three-year Efficacy, Safety, and Immunogenicity of Ustekinumab Treatment of Crohn's Disease', Journal of Crohn's & Colitis, vol. 14, no. 1, pp. 23-32. https://doi.org/10.1093/ecco-jcc/jjz110

Iacucci, M, Ghosh, S & Gardner, L (ed.) 2020, 'Impact of COVID-19 outbreak on the care of patients with inflammatory bowel disease: a comparison before and after the outbreak in South China: Impact of COVID-19 on patients with IBD', Journal of Gastroenterology and Hepatology.

Iacucci, M, Ghosh, S & Gardner, L (ed.) 2020, 'Involvement of digestive system in Covid-19: manifestations, pathology, management and challenges', Therapeutic Advances in Gastroenterology, vol. 13, pp. 1-12. https://doi.org/10.1177/1756284820934626

Mao, R, Qiu, Y, He, J-S, Tan, J-Y, Li, X-H, Liang, J, Shen, J, Zhu, L-R, Chen, Y, Iacucci, M, Ng, SC, Ghosh, S & Chen, M-H 2020, 'Manifestations and prognosis of gastrointestinal and liver involvement in patients with COVID-19: a systematic review and meta-analysis', The Lancet Gastroenterology and Hepatology, vol. 5, no. 7, pp. 667-678. https://doi.org/10.1016/S2468-1253(20)30126-6

Gui, X, Iacucci, M, Ghosh, S, Ferraz, JGP & Lee, S 2020, 'Revisiting the distinct histomorphologic features of inflammatory bowel disease-associated neoplastic precursor lesions in the SCENIC and post-DALM Era', Human Pathology, vol. 100, pp. 24-37. https://doi.org/10.1016/j.humpath.2020.04.010

Abstract

Jeffery, LE, Shivaji, UN, Zardo, D, Acharjee, A, Nardone, OM, Smith, SC, Gkoutos, G, Visweswariah, SS, Ghosh, S & Iacucci, M 2020, 'P005 Regulators of the guanylate cyclase pathway are potential novel markers of mucosal healing in IBD', Journal of Crohn's & Colitis, vol. 14, no. Supplement_1, pp. S131–S132. https://doi.org/10.1093/ecco-jcc/jjz203.134

Review article

Nardone, O, Iaccuci, M, Ghosh, S & Castiglione, F 2020, 'Can a transition clinic bridge the gap between paediatric and adult inflammatory bowel disease', Digestive and Liver Disease, vol. 52, no. 5, pp. 516-527. https://doi.org/10.1016/j.dld.2020.02.009

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