Recent publications
Article
Khan, S, Mahgoub, S, Fallatah, N, Lalor, PF & Newsome, PN 2023, 'Liver disease and cell therapy - advances made and remaining challenges', Stem Cells. https://doi.org/10.1093/stmcls/sxad029
Garg, A, Khan, S, Luu, N, Nicholas, DJ, Day, V, King, AL, Fear, J, Lalor, PF & Newsome, PN 2023, 'TGFβ1 priming enhances CXCR3-mediated mesenchymal stromal cell engraftment to the liver and enhances anti-inflammatory efficacy', Journal of Cellular and Molecular Medicine, vol. 27, no. 6, pp. 864-878. https://doi.org/10.1111/jcmm.17698
James, BH, Papakyriacou, P, Gardener, MJ, Gliddon, L, Weston, CJ & Lalor, PF 2022, 'The Contribution of Liver Sinusoidal Endothelial Cells to Clearance of Therapeutic Antibody', Frontiers in Physiology, vol. 12, 753833. https://doi.org/10.3389/fphys.2021.753833
Coltman, NJ, Coke, BA, Chatzi, K, Shepherd, EL, Lalor, PF, Schulz-Utermoehl, T & Hodges, NJ 2021, 'Application of HepG2/C3A liver spheroids as a model system for genotoxicity studies', Toxicology Letters, vol. 345, pp. 34-45. https://doi.org/10.1016/j.toxlet.2021.04.004
Sheriff, L & Lalor, P 2021, 'The impact of the NLRP3 pathway in the pathogenesis of non-alcoholic fatty liver disease and alcohol-related liver disease', Livers, vol. 1, no. 2, pp. 68-81. https://doi.org/10.3390/livers1020007
Sheriff, L, Khan, RS, Saborano, R, Wilkin, R, Luu, N, Gunther, UL, Hubscher, SG, Newsome, PN & Lalor, PF 2020, 'Alcoholic hepatitis and metabolic disturbance in female mice: a more tractable model than Nrf2-/- animals', Disease Models & Mechanisms, vol. 13, no. 12, dmm046383. https://doi.org/10.1242/dmm.046383
Shepherd, EL, Karim, S, Newsome, PN & Lalor, PF 2020, 'Inhibition of vascular adhesion protein-1 modifies hepatic steatosis in vitro and in vivo', World journal of hepatology, vol. 12, no. 11, pp. 931-948. https://doi.org/10.4254/wjh.v12.i11.931
Shepherd, E, Saborano, R, Northall, E, Matsuda, K, Ogino, H, Yashiro, H, Pickens, J, Feaver, RE, Cole, BK, Hoang, SA, Lawson, MJ, Olson, M, Figler, RA, Reardon, JE, Nishigaki, N, Wamhoff, BR, Gunther, U, Hirschfield, G, Erion, DM & Lalor, T 2020, 'Ketohexokinase inhibition improves NASH by reducing fructose-induced steatosis and fibrogenesis', JHEP Reports, vol. 2020, 100217. https://doi.org/10.1016/j.jhepr.2020.100217
Chauhan, A, Sheriff, L, Hussain, MT, Webb, GJ, Patten, DA, Shepherd, EL, Shaw, R, Weston, CJ, Haldar, D, Bourke, S, Bhandari, R, Watson, S, Adams, DH, Watson, SP & Lalor, PF 2020, 'The platelet receptor CLEC-2 blocks neutrophil mediated hepatic recovery in acetaminophen induced acute liver failure', Nature Communications, vol. 11, no. 1, 1939. https://doi.org/10.1038/s41467-020-15584-3
Saborano, R, Lalor, P & Gunther, U 2019, 'A framework for tracer-based metabolism in mammalian cells by NMR', Scientific Reports, vol. 9, no. 1, 2520 (2019), pp. 2520. https://doi.org/10.1038/s41598-018-37525-3
Malehmir, M, Pfister, D, Gallage, S, Szydlowska, M, Inverso, D, Kotsiliti, E, Leone, V, Peiseler, M, Surewaard, BGJ, Rath, D, Ali, A, Wolf, MJ, Drescher, H, Healy, ME, Dauch, D, Kroy, D, Krenkel, O, Kohlhepp, M, Engleitner, T, Olkus, A, Sijmonsma, T, Volz, J, Deppermann, C, Stegner, D, Helbling, P, Nombela-Arrieta, C, Rafiei, A, Hinterleitner, M, Rall, M, Baku, F, Borst, O, Wilson, CL, Leslie, J, O'Connor, T, Weston, CJ, Adams, DH, Sheriff, L, Teijeiro, A, Prinz, M, Bogeska, R, Anstee, N, Bongers, MN, Notohamiprodjo, M, Geisler, T, Withers, DJ, Ware, J, Mann, DA, Augustin, HG, Vegiopoulos, A, Milsom, MD, Rose, AJ, Lalor, PF, Llovet, JM, Pinyol, R, Tacke, F, Rad, R, Matter, M, Djouder, N, Kubes, P, Knolle, PA, Unger, K, Zender, L, Nieswandt, B, Gawaz, M, Weber, A & Heikenwalder, M 2019, 'Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer', Nature Medicine, vol. 25, no. 4, pp. 641-655. https://doi.org/10.1038/s41591-019-0379-5
Rahman, H-U, Bhogal, R & Lalor, P 2018, 'Models for predicting risk of acute kidney injury after liver surgery', OBM Hepatology and Gastroenterology, vol. 2, no. 2, 007. https://doi.org/10.21926/obm.hg.1802007
Chauhan, A, Adams, D, Watson, S & Lalor, P 2017, 'Blocking platelet activation enhances neutrophil driven liver repair after acute toxic liver injury', Journal of Hepatology. https://doi.org/10.1016/S0168-8278(17)30992-3
Editorial
Adams, DH, Shepherd, EL & Lalor, PF 2018, 'Could endothelial TGFβ signaling be a promising new target for liver disease?', Expert review of gastroenterology & hepatology, vol. 12, no. 7, pp. 637-639. https://doi.org/10.1080/17474124.2018.1477587
Review article
Shetty, S, Lalor, PF & Adams, DH 2018, 'Liver sinusoidal endothelial cells - gatekeepers of hepatic immunity', Nature Reviews. Gastroenterology & Hepatology. https://doi.org/10.1038/s41575-018-0020-y
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