Dr Latika Gupta MD, MRCP, DM

Dr Latika Gupta

Department of Inflammation and Ageing
Associate Professor
Consultant Rheumatologist

Contact details

Email
l.gupta@bham.ac.uk
Address
Department of Inflammation and Ageing
College of Medicine and Health
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Dr Latika Gupta is a Consultant Rheumatologist and Associate Professor specialising in inflammatory myopathies, combining clinical expertise with digital innovation to advance precision medicine approaches for autoimmune diseases globally.

Qualifications

  • Specialist Certification UK, 2023
  • MRCP UK, 2022
  • MRCP (SCE Rheumatology), 2018
  • Specialty training in rheumatology, DM (Clinical Immunology and Rheumatology, 2013-17), Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow
  • Postgraduate training: MD (General Medicine, 2010-13), Lady Hardinge Medical College, Delhi University
  • Undergraduate medical training: Manipal University (2003-08, graduated top of the class)

Biography

Dr. Gupta's career bridges healthcare systems across continents, shaped by her unique training path from specialist certification in Asia to retraining in the UK. Enhanced by international fellowships in the USA (UPenn), UK (University of Oxford & Bath), Sweden (Karolisnka Institute), and Australia (Melbourne University), this global perspective drives her scientific enquiry to understanding and eliminating ethnic and regional disparities in healthcare outcomes. It is the foundation of her work, which seeks to create a world where a patient’s background does not determine their health outcome.

Trained in clinical and translational sciences, Dr. Gupta established the MyoCite biorepository of 350+ myositis patients with longitudinal data and autoantibody profiling. Her characterization of inflammatory myopathies in diverse populations revealed unique antibody profiles and clinical manifestations, particularly a 50% prevalence of anti-MDA5 antibodies with distinctive presentations in darker skin tones. This work identified novel biomarkers of muscle strength and accelerated senescence while documenting higher early mortality from atypical infections.

Her current research integrates large language models into rheumatology practice, developing automated disease scoring for muscle and skin conditions, digital triage systems for osteoporosis, and AI-assisted diagnosis of complex conditions. These applications demonstrate performance comparable to human evaluators while expanding access to specialized care.

With recognized expertise in as a researcher (280 publications, 6000+ citations, H-index 34), she holds key positions in various international organizations, including Chair of the IMACS Telemedicine Special Interest Group, Chair of APLAR Young Rheumatology Partnerships Committee, and Co-Convenor of the EULAR task force on Big Data and AI.

Featured in Lancet Rheumatology as an inspiring early career researcher, she is recognized for her contributions to myositis research.

Teaching

Clinical Teaching

  • Educational Supervisor for junior and senior clinical fellows (NHS, 2021-2024) and Clinical Supervisor for senior clinical fellows in rheumatology (2022-ongoing)
  • Medical student teaching and grand rounds presentations (2021-24)
  • Procedural training supervision: joint injections and muscle biopsies (2022-24)

Specialty Training Programme Contributions

  • Mentoring rheumatology specialty trainees with daily academic sessions, examination preparation, and curriculum development (2018-2021)
  • Laboratory teaching including autoantibody interpretation workshops for rheumatology specialty registrars (2018-21)

Postgraduate supervision

Supervision and Mentorship Experience

Dr Gupta has supervised 6 postgraduate and specialty trainees to completion (1 PhD, 1 MSc, 4 DM Rheumatology trainees) and maintains active supervision of current doctoral and masters students. Recent completions include co-supervision of MSc students at City University Birmingham (AI analytics for social media data, 2024) and University of Manchester (Pain in inflammatory myopathies, 2023-24), plus PhD supervision in Immunology (Pathophysiology of Osteoarthritis, 2020-24) and DM Rheumatology trainees (Complications in inflammatory myopathies, 2018-2021).

International Teaching and Training Leadership

Dr Gupta delivers research methodology training in various international platforms: academic fellowship programmes at Lviv University, Ukraine (2019-2023); undergraduate medical education through Indian Association of Geriatrics; and coordination of the Connecting Researchers mentorship programme (2020-22). Has conducted virtual workshops in research methodology and social media applications in medicine with global participation.

Professional Mentorship Leadership

  • IMACS Mentorship Lead (2023-ongoing): Career mentorship in muscle diseases through integrated virtual/face-to-face programmes.
  • IMG Mentorship: Mentored 80+ International Medical Graduates in research methodology, academic publishing, achieving success rates in international medical examinations.

Current Doctoral Supervision Interests

  • AI applications in healthcare data analytics, including Automated Language Models for clinical decision support
  • Environmental factors in autoimmune disease development and progression
  • Precision medicine approaches for management of muscle conditions

For doctoral research enquiries, please contact Dr Gupta directly or email the graduate school.

Research

Characterisation of Myositis in Diverse Populations

Dr Gupta has published  on Indian demographic characteristics, complications, and outcomes research in myositis. Through the MyoCite cohort and linked bio-repository, her work has explored autoantibodies, biomarkers of accelerated immunosenescence and non-immune pathways including metabolomics. 

Recently the MARC (Myositis Audit and Research Collaborative) network has examined current clinical practices and identified opportunities for improving outcomes and guideline adherence through enhanced clinical workflows. In 2025 extended MyoCite consortia collaborations published on flares and natural history outcomes in inflammatory myopathies. 

The COVAD Study

Dr Gupta established the international COVAD study, conducting three phases that generated datasets totalling 55,000 patient responses. Initially exploring pandemic impact and outcomes with COVID-19 infection, the programme evolved to collate patient voices in autoimmune diseases, examining self-efficacy, wellbeing, dietary interventions, and complementary health modalities. Her analysis has informed her contributions to the EULAR vaccination guidelines and work towards telemedicine recommendations for muscle diseases.

Education and Equity Innovation

With the CHANGE consortium, research on gender equity has contributed to professional discourse and policy development. Her work includes social media declarations for priorities in rheumatology, mapping the global rheumatology social media landscape, and developing workflows for social media editors.

Dr Gupta's experience spanning various regions has informed collaborations and work towards a vision of collaborative partnership models for young rheumatology mentoring. She has examined the soft skills training needs for young rheumatology trainees. Her interests include partnerships between international young rheumatologist leagues, creating frameworks that support growth among motivated young specialists through integrated digital and traditional mentorship approaches.

Other activities

  • Committee member, Registers and Research, BSR
  • Lead - APLAR Young Rheumatology Partnerships Committee
  • Member, EULAR Pediatric committee
  • Core group member, Pres JDM working group
  • IMACS Mentorship Lead
  • Co-lead- MIHRA mentorship program
  • BSR AI special interest group
  • Digital Rheumatology Network

Publications

Recent publications

Article

Duc, NTM, Dila, KAS, Nguyen, DH, Eltaybani, S, Singal, AG, Siddiqui, AR, Piault-Louis, E, Fradelos, EC, Ansar, F, Maselli, F, Han, H, Hill, J, Karbwang, J, Gupta, L, Verra, ML, Karamouzian, M, Nair, RC, Bronner, S, Adhikari, TB, Tran, US, Havshøj, U, Hedley, D, Carpenter, DM, da Costa, FA, Esposito, F, Rivet Amico, K, McInnes, MDF, Safdar, N, Vaghela, G & Huy, NT 2025, 'A checklist for translating and adapting questionnaires (CTAQ) in healthcare research: insights from a Delphi method approach', Tropical Medicine and Health, vol. 53, no. 1, 154. https://doi.org/10.1186/s41182-025-00798-2

COVAD Study Group, Hoff, LS, Ravichandran, N, Sen, P, Day, J, Joshi, M, Nune, A, Nikiphorou, E, Saha, S, Tan, AL, Shinjo, SK, Ziade, N, Velikova, T, Milchert, M, Jagtap, K, Parodis, I, Gracia-Ramos, AE, Cavagna, L, Kuwana, M, Knitza, J, Chen, YM, Makol, A, Agarwal, V, Patel, A, Pauling, JD, Wincup, C, Barman, B, Tehozol, EAZ, Serrano, JR, Torre, IG-DL, Colunga-Pedraza, IJ, Merayo-Chalico, J, Chibuzo, OC, Katchamart, W, Goo, PA, Shumnalieva, R, El Kibbi, L, Halabi, H, Vaidya, B, Shaharir, SS, Hasan, ATMT, Dey, D, Gutiérrez, CET, Caballero-Uribe, CV, Lilleker, JB, Salim, B, Gheita, T, Chatterjee, T, Distler, O, Saavedra, MA, Chinoy, H, Agarwal, V, Aggarwal, R & Gupta, L 2025, 'Characteristics of and risk factors for COVID-19 breakthrough infections in idiopathic inflammatory myopathies: results from the COVAD study', Rheumatology (Oxford, England), vol. 64, no. 2, pp. 597-606. https://doi.org/10.1093/rheumatology/keae128

COVAD Study Group, Ali, SS, Demetriou, C, Parodis, I, Tan, AL, Edgar Gracia-Ramos, A, Joshi, M, Caballero-Uribe, CV, Saha, S, Lilleker, JB, Nune, A, Pauling, JD, Wincup, C, Jagtap, K, Dey, D, Milchert, M, Distler, O, Chinoy, H, Agarwal, V, Gupta, L & Nikiphorou, E 2025, 'Determinants of physical function, as measured using PROMIS PF-10a, in patients with rheumatoid arthritis: results from the international COVID-19 Vaccination in Autoimmune Diseases (COVAD) study', Rheumatology Advances in Practice, vol. 9, no. 1, rkae154. https://doi.org/10.1093/rap/rkae154

COVAD Study 2025, 'Disease burden in inflammatory arthritis: an unsupervised machine learning approach of the COVAD-2 e-survey dataset', Rheumatology Advances in Practice, vol. 9, no. 2, rkaf031. https://doi.org/10.1093/rap/rkaf031

Schreiber, K, Graversgaard, C, Parodis, I, Agmon-Levin, N, Aguilera, S, Antovic, A, Bertsias, GK, Bini, I, Bobirca, A, Capela, S, Cervera, R, Costedoat-Chalumeau, N, Dolhain, R, Etomi, O, Flint, J, Fonseca, JE, Fritsch-Stork, R, Förger, F, Giles, I, Goulden, B, Götestam Skorpen, C, Gunnarsson, I, Gupta, L, Koksvik, HS, Linde, L, Lykke, J, Meissner, Y, Molto, A, Moore, L, Mosca, M, Nelson-Piercy, C, Perez-Garcia, LF, Raio, L, Rom, AL, Rottenstreich, A, Saleh, M, Sciascia, S, Strangfeld, A, Svenungsson, E, Tektonidou, MG, Tincani, A, Troldborg, A, Vojinovic, J, Voss, A, Wallenius, M, Zuniga-Serrano, N & Andreoli, L 2025, 'Impact of conflicting information on the use of antirheumatic drugs in pregnancy and breastfeeding: perspectives of healthcare providers from the global PRAISE survey', Therapeutic Advances in Musculoskeletal Disease, vol. 17. https://doi.org/10.1177/1759720X251350087

Editorial

Shivakumar, K, Teh, I, Gupta, L & Day, J 2025, 'Classification in Idiopathic Inflammatory Myopathies: Where Are We Now?', International Journal of Rheumatic Diseases, vol. 28, no. 7, e70295. https://doi.org/10.1111/1756-185X.70295

Gupta, L, Nikiphorou, E, Carmona, L, Santos, CS, Berenbaum, F, Edwards, CJ & EULAR SoMeR Study Group 2025, 'Declaration on the use of social media for rheumatology professionals', RMD Open, vol. 11, no. 3, e005917. https://doi.org/10.1136/rmdopen-2025-005917

Desai, D, Gupta, L & Vignesh, P 2025, 'Epidemiology of Juvenile Dermatomyositis—What We Know and What More Is Needed?', International Journal of Rheumatic Diseases, vol. 28, no. 7, e70347. https://doi.org/10.1111/1756-185X.70347

APLAR myositis SIG, Parihar, J, Gono, T, So, H & Gupta, L 2025, 'Infections in Idiopathic Inflammatory Myopathies: Do Asians Need a Different Dose of Immunosuppression?', International Journal of Rheumatic Diseases, vol. 28, no. 1, e70084. https://doi.org/10.1111/1756-185X.70084

Letter

Rahulan, LM, Anuja, AK, Agarwal, V & Gupta, L 2025, 'ADA2 Levels in Anti-MDA-5-Positive Idiopathic Inflammatory Myopathies in the MyoCite Cohort', International Journal of Rheumatic Diseases, vol. 28, no. 2, e15438. https://doi.org/10.1111/1756-185X.15438

Del Vescovo, S, Vij, P, Casteleyn, C, Coskun Benlidayi, I, Jasim, M, Adizie, T, Sapkota, H, Venkatachalam, S, Gupta, L & Venerito, V 2025, 'Clinical utility of large language models for osteoporosis referral triage: a pilot study', RMD Open, vol. 11, no. 2, e005604. https://doi.org/10.1136/rmdopen-2025-005604

Venerito, V, Gupta, L, Mileto, S, Iannone, F & Bilgin, E 2025, 'Ethical challenges and regulatory pathways for artificial intelligence in rheumatology', Rheumatology Advances in Practice, vol. 9, no. 2, rkaf035. https://doi.org/10.1093/rap/rkaf035

Review article

La Bella, S, Gupta, L & Venerito, V 2025, 'AI am the future: artificial intelligence in pediatric rheumatology', Current Opinion in Rheumatology. https://doi.org/10.1097/BOR.0000000000001087

Pellico, MR, Day, J, Shah, M, Yi, BY, Saketkoo, LA, Lood, C & Gupta, L 2025, 'Biorepositories For Global Rare Disease Research: A Narrative Review', Current Rheumatology Reports, vol. 27, no. 1, 24. https://doi.org/10.1007/s11926-025-01189-6

Nagendra, L, Agarwal, K, Patra, S, Bhattacharya, S, Gupta, L, Talwar, N, Rao, A, Gupta, A, Kamrul-Hasan, ABM, Dutta, D, Hiligsmann, M & Chandran, M 2025, 'Optimizing Bone Health in Diabetes: Strategies for Fracture Risk Reduction in Public Healthcare', Current Diabetes Reports, vol. 25, no. 1, 43. https://doi.org/10.1007/s11892-025-01599-x

Expertise

Dr Gupta has a dedicated interest in myositis, equity, and digital health. She is  a clinician scientist with background of laboratory and translational research, cohort building, and big datasets, and is currently undertaking training to be a EULAR methodologist. 

Expertise

  • Member, EULAR Task Force on Vaccination in Rheumatic Diseases
  • Co-Methodologist for IMACS-CARRA-SHARE Consensus JDM Guidelines Group

Policy experience

2025
Committee member, Registers and Research, BSR
BSR AI special interest group
Co-Convenor EULAR task force on Big Data and AI
Co-Methodologist Cancer in Autoimmune Conditions task force

2024
Lead APLAR Young Rheumatology Partnerships Committee
Member, EULAR Pediatric committee
Member, EULAR Task Force on Vaccination in Rheumatic Diseases Core group member, Pres JDM working group

2023
Chair, IMACS (International Myositis Collaborative group) Telemedicine special interest group
Lead- IMACS mentorship program
Co-Lead MIHRA biospecimen group
EMEUNET Committee Member in EULAR (June 2023-25)
Lead, EULAR Research Study Group on Social Media for Rheumatology Healthcare Professionals (SoMeR)