Professor Janet M Lord FMedSci

Image of Professor Janet Lord

Institute of Inflammation and Ageing
Director of the Institute of Inflammation and Ageing Director of the MRC-Arthritis Research UK Centre for Musculoskeletal Ageing Research

Contact details

Institute of Inflammation and Ageing
Birmingham University Research labs.
Queen Elizabeth Hospital
Mindelsohn Way,
B15 2WB

Janet Lord is Director of the Institute of Inflammation and Ageing, a multidisciplinary research institute which brings together fundamental scientists and clinicians to translate understanding of the process of inflammation in to new treatments for chronic age-related inflammatory disease and the consequences of major trauma.

Her own research focusses on the dysregulation of immunity in old age, in particular the decline in neutrophil function and how this compromises the response to infection and tissue injury. She aims to understand the mechanism involved and to develop novel therapies to improve immunity in older adults.


  • Professor of Immune Cell Biology
  • Fellow of the Academy of Medical Sciences 2015
  • PhD Biological Sciences 1983
  • BSc (Hons) Human Biology 1979


Module lead, Biology of Ageing, BSc Medical Science

Lecturer, Immunology and Haematology module, MBChB

Postgraduate supervision

Professor Lord supervises doctoral research in the following areas:

The mechanisms underlying reduced neutrophil function in ageing
Lifestyle factors (exercise, diet, sleep) influencing immune function in old age
Stress and immunity

Other activities

  • Section editor for the Journal Ageing Cell


Recent publications


Chimen, M, Evryviadou, A, Box, CL, Harrison, MJ, Hazeldine, J, Dib, LH, Kuravi, SJ, Payne, H, Price, JMJ, Kavanagh, D, Iqbal, AJ, Lax, S, Kalia, N, Brill, A, Thomas, SG, Belli, A, Crombie, N, Adams, RA, Evans, S-A, Deckmyn, H, Lord, JM, Harrison, P, Watson, SP, Nash, GB & Rainger, GE 2019, 'Appropriation of GPIb╬▒ from platelet-derived extracellular vesicles supports monocyte recruitment in systemic inflammation', Haematologica.

Dinsdale, R, Hazeldine, J, Al-Tarrah, K, Hampson, P, Devi, A, Ermogenous, C, Bamford, A, Bishop, J, watts, S, kirkman, E, dalle lucca, J, midwinter, M, woolley, T, Foster, M, Lord, J, Moiemen, N & Harrison, P 2019, 'Dysregulation of the actin scavenging system and inhibition of DNAse activity following severe thermal injury', British Journal of Surgery.

Hazeldine, J, Harrison, P, Dinsdale, R & Lord, J 2019, 'Traumatic injury and exposure to mitochondrial-derived damage associated molecular patterns suppresses neutrophil extracellular trap formation', Frontiers in immunology.

Welch, C, Greig, CA, Hassan-Smith, ZK, Pinkney, TD, Lord, JM & Jackson, TA 2019, 'A pilot observational study measuring acute sarcopenia in older colorectal surgery patients', BMC Research Notes, vol. 12, no. 1, 24.

Wilson, D, Breen, L, Lord, JM & Sapey, E 2018, 'The challenges of muscle biopsy in a community based geriatric population', BMC Research Notes, vol. 11, no. 1, 830.

Prete, A, Yan, Q, Al-Tarrah, K, Akturk, H, Prokop, L, Alahdab, F, Foster, MA, Lord, J, Karavitaki, N, Wass, J, Murad, M, Arlt, W & Bancos, I 2018, 'The cortisol stress response induced by surgery: a systematic review and meta-analysis', Clinical Endocrinology, pp. 554-567.

Pearson, M, Bik, M, Ospelt, C, Naylor, A, Wehmeyer, C, Jones, S, Buckley, C, Gay, S, Filer, A & Lord, J 2018, 'Endogenous Galectin-9 suppresses apoptosis in human rheumatoid arthritis synovial fibroblasts', Scientific Reports, vol. 8, 12887.

Duggal, NA, Snelson, C, Shaheen, U, Pearce, V & Lord, JM 2018, 'Innate and adaptive immune dysregulation in critically ill ICU patients', Scientific Reports, vol. 8, no. 1, 10186.,

Rushton, AB, Evans, DW, Middlebrook, N, Heneghan, NR, Small, C, Lord, J, Patel, JM & Falla, D 2018, 'Development of a screening tool to predict the risk of chronic pain and disability following musculoskeletal trauma: Protocol for a prospective observational study in the United Kingdom', BMJ open, vol. 8, no. 4, e017876.

Chapter (peer-reviewed)

Whittaker, A, Duggal, N, Oyebode, JR & Lord, J 2018, Understanding Immunesenescence. in A Walker (ed.), The New Dynamics of Ageing Vol II: Biological Perspectives: Biological Perspectives. 1 edn, vol. 2, Policy Press, Bristol, pp. 107-130.


Price, J, Lord, J & Harrison, P 2019, '"Inflammaging and Platelet Hyperreactivity:- A new therapeutic target?"', Journal of thrombosis and haemostasis : JTH.

Review article

Doody, P, Aunger, J, Asamane, E, Greig, C, Lord, J & Whittaker, A 2019, 'Frailty Levels In Geriatric Hospital paTients (FLIGHT)-the prevalence of frailty among geriatric populations within hospital ward settings: a systematic review protocol', BMJ open, vol. 9, no. 8, e030147, pp. 1-5.

Duggal, N, Niemiro, G, Simpson, R, Harridge, S & Lord, J 2019, 'Can physical activity ameliorate immunosenescence and thereby reduce age-related multi-morbidity?', Nature Reviews Immunology. s41577-019-0177-9

Al-Tarrah, K, Jones, S, Moiemen, N & Lord, J 2019, 'Potential role of adipose tissue and its hormones in burns and critically ill patients', Burns.

Sullivan, J, Mirbahai, L & Lord, J 2018, 'Major trauma and acceleration of the ageing process', Ageing Research Reviews, vol. 48, pp. 32-39.

View all publications in research portal