Recent publications
Article
Mahida, RY, Lax, S, Bassford, CR, Scott, A, Parekh, D, Hardy, RS, Naidu, B, Matthay, MA, Stewart, PM, Cooper, MC, Perkins, GD & Thickett, DR 2023, 'Impaired alveolar macrophage 11β-hydroxysteroid dehydrogenase type 1 reductase activity contributes to increased pulmonary inflammation and mortality in sepsis-related ARDS', Frontiers in immunology, vol. 14, 1159831. https://doi.org/10.3389/fimmu.2023.1159831
Grudzinska, F, Jasper, A, Sapey, E, Thickett, D, Mauro, C, Scott, A & Barlow, J 2023, 'Real-time assessment of neutrophil metabolism and oxidative burst using extracellular flux analysis', Frontiers in immunology, vol. 14, 1083072. https://doi.org/10.3389/fimmu.2023.1083072
Mahida, RY, Price, J, Lugg, ST, Li, H, Parekh, D, Scott, A, Harrison, P, Matthay, MA & Thickett, DR 2022, 'CD14-positive extracellular vesicles in bronchoalveolar lavage fluid as a new biomarker of acute respiratory distress syndrome', American journal of physiology. Lung cellular and molecular physiology, vol. 322, no. 4, pp. L617-L624. https://doi.org/10.1152/ajplung.00052.2022
Mckelvey, MC, Abladey, AA, Small, DM, Doherty, DF, Williams, R, Scott, A, Spek, CA, Borensztajn, KS, Holsinger, L, Booth, R, O’kane, CM, Mcauley, DF, Taggart, CC & Weldon, S 2022, 'Cathepsin S contributes to lung inflammation in acute respiratory distress syndrome', American Journal of Respiratory and Critical Care Medicine, vol. 205, no. 7, pp. 769-782. https://doi.org/10.1164/rccm.202107-1631oc
Belchamber, KBR, Thein, OS, Hazeldine, J, Grudzinska, FS, Faniyi, A, Hughes, M, Jasper, A, Yip, KP, Crowley, LE, Lugg, ST, Sapey, E, Parekh, D, Thickett, DR & Scott, A 2022, 'Dysregulated neutrophil phenotype and function in hospitalised non-ICU COVID-19 pneumonia', Cells, vol. 11, no. 18, 2901. https://doi.org/10.3390/cells11182901
Li, H, Li, X, Hao, Y, Wu, C, Fu, Y, Su, N, Chen, H, Ying, B, Wang, H, Su, L, Cai, H, He, Q, Cai, M, Sun, J, Lin, J, Scott, A, Smith, F, Huang, X & Jin, S 2022, 'Maresin 1 intervention reverses experimental pulmonary arterial hypertension in mice', British Journal of Pharmacology, vol. 179, no. 22, pp. 5132-5147. https://doi.org/10.1111/bph.15906
Lugg, ST, Mackay, WR, Faniyi, AA, Faustini, SE, Webster, C, Duffy, JE, Hewison, M, Shields, AM, Parekh, D, Richter, AG, Scott, A & Thickett, DR 2022, 'Vitamin D status: a U-shaped relationship for SARS-CoV-2 seropositivity in UK healthcare workers', BMJ Open Respiratory Research, vol. 9, no. 1, e001258. https://doi.org/10.1136/bmjresp-2022-001258
Nicholson, T, Davis, L, Davis, ET, Ede, MN, Scott, A & Jones, SW 2022, 'e-Cigarette vapour condensate reduces viability and impairs function of human osteoblasts, in part, via a nicotine dependent mechanism', Toxics, vol. 10, no. 9, 506. https://doi.org/10.3390/toxics10090506
Mahida, RY, Scott, A, Parekh, D, Lugg, ST, Hardy, RS, Lavery, GG, Matthay, MA, Naidu, B, Perkins, GD & Thickett, DR 2021, 'Acute respiratory distress syndrome is associated with impaired alveolar macrophage efferocytosis', The European respiratory journal, vol. 58, no. 3, 2100829. https://doi.org/10.1183/13993003.00829-2021
Mahida, RY, Scott, A, Parekh, D, Lugg, ST, Belchamber, KBR, Hardy, RS, Matthay, MA, Naidu, B & Thickett, DR 2021, 'Assessment of Alveolar Macrophage Dysfunction Using an in vitro Model of Acute Respiratory Distress Syndrome', Frontiers in Medicine, vol. 8, 737859. https://doi.org/10.3389/fmed.2021.737859
Editorial
Scott, A, Weldon, S & Taggart, C 2022, 'The serpin-tine search for factors associated with COVID-19 severity in patients with COPD', American Journal of Respiratory and Critical Care Medicine, vol. 206, no. 6, pp. 657-658. https://doi.org/10.1164/rccm.202205-0956ed
Preprint
Belchamber, K, Thein, O, Hazeldine, J, Grudzinska, F, Hughes, M, Jasper, A, Yip, KP, Sapey, E, Parekh, D, Thickett, D & Scott, A 2021 'Altered neutrophil phenotype and function in non-ICU hospitalised COVID-19 patients correlated with disease severity' medRxiv. https://doi.org/10.1101/2021.06.08.21258535
Mahida, RY, Price, J, Lugg, ST, Li, H, Parekh, D, Scott, A, Harrison, P, Matthay, MA & Thickett, DR 2021 'CD14 positive extracellular vesicles in broncho-alveolar lavage fluid as a new biomarker of acute respiratory distress syndrome' medRxiv. https://doi.org/10.1101/2021.09.25.21264053
Review article
Davis, LC, Sapey, E, Thickett, DR & Scott, A 2022, 'Predicting the pulmonary effects of long-term e-cigarette use: are the clouds clearing?', European Respiratory Review, vol. 31, no. 163, 210121. https://doi.org/10.1183/16000617.0121-2021
Lugg, ST, Scott, A, Parekh, D, Naidu, B & Thickett, DR 2021, 'Cigarette smoke exposure and alveolar macrophages: mechanisms for lung disease', Thorax, vol. 77, no. 1, pp. 94-101. https://doi.org/10.1136/thoraxjnl-2020-216296
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