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Roberts, A, Tang, T, Stewart, F, Pallini, C, Wallace, G, Cooper, A, Scott, A, Thickett, D, Lugg, S, Pinkney, T, Taylor, G, Brock, K, Stamataki, Z, Brady, CA, Curnow, J, Gordon, J, Qureshi, O, Barnes, N, Bentley, L, Juvvanapudi, J, Bancroft, H, Hemming, B, Ferris, C, Langman, G, Robinson, A, Chapman, J & Naidu, B 2021, 'Ex vivo modelling of PD-1/PD-L1 immune checkpoint blockade under acute, chronic, and exhaustion-like conditions of T-cell stimulation', Scientific Reports, vol. 11, 4030. https://doi.org/10.1038/s41598-021-83612-3
Mahida, RY, Chotalia, M, Alderman, J, Patel, C, Hayden, A, Desai, R, Beesley, E, Crowley, LE, Soltan, M, Bangash, M, Parekh, D, Patel, J & Thickett, DR 2020, 'Characterisation and outcomes of ARDS secondary to pneumonia in patients with and without SARS-CoV-2: a single-centre experience', BMJ Open Respiratory Research, vol. 7, no. 1, e000731. https://doi.org/10.1136/bmjresp-2020-000731
EME-TIPAC team 2020, 'Effect of co-trimoxazole (trimethoprim-sulfamethoxazole) vs placebo on death, lung transplant, or hospital admission in patients with moderate and severe idiopathic pulmonary fibrosis: the EME-TIPAC randomized clinical trial', JAMA The Journal of the American Medical Association, vol. 324, no. 22, pp. 2282-2291. https://doi.org/10.1001/jama.2020.22960
Grudzinska, F, Brodlie, M, Scholefield, B, Jackson, T, Scott, A, Thickett, D & Sapey, E 2020, 'Neutrophils in community-acquired pneumonia: parallels in dysfunction at the extremes of age', Thorax, vol. 75, no. 2, pp. 164-171. https://doi.org/10.1136/thoraxjnl-2018-212826
ISARIC4C Investigators 2020, 'Outcome of hospitalization for COVID-19 in patients with interstitial lung disease: an international multicenter study', American Journal of Respiratory and Critical Care Medicine, vol. 202, no. 12, pp. 1656-1665. https://doi.org/10.1164/rccm.202007-2794OC
Lugg, ST, Kerr, A, Kadiri, S, Budacan, A-M, Farley, A, Perski, O, West, R, Brown, J, Thickett, DR & Naidu, B 2020, 'Protocol for a feasibility study of smoking cessation in the surgical pathway before major lung surgery: Project MURRAY', BMJ open. https://doi.org/10.1136/bmjopen-2019-036568
Zheng, S, Yang, J, Hu, X, Li, M, Wang, Q, Dancer, RCA, Parekh, D, Gao-Smith, F, Thickett, DR & Jin, S 2020, 'Vitamin D attenuates lung injury via stimulating epithelial repair, reducing epithelial cell apoptosis and inhibits TGF-β induced epithelial to mesenchymal transition', Biochemical Pharmacology, vol. 177, 113955. https://doi.org/10.1016/j.bcp.2020.113955
Faniyi, A, Lugg, S, Faustini, S, Webster, C, Duffy, J, Hewison, M, Shields, A, Nightingale, PG, Richter, A & Thickett, D 2020, 'Vitamin D status and seroconversion for COVID-19 in UK healthcare workers', European Respiratory Journal. https://doi.org/10.1183/13993003.04234-2020
Lugg, ST, Alridge, KA, Howells, PA, Parekh, D, Scott, A, Mahida, RY, Park, D, Tucker, O, Gao, F, Perkins, GD, Thickett, DR & Dancer, RCA 2019, 'Dysregulated alveolar function and complications in smokers following oesophagectomy', ERJ Open Research, vol. 5, no. 1, 00089. https://doi.org/10.1183/23120541.00089-2018
Grudzinska, F, Aldridge, K, Hughes, S, Nightingale, P, Bangnash, M, Dancer, R, Parekh, D, Patel, J, Sapey, E & Thickett, D 2019, 'Early identification of severe community-acquired pneumonia: a retrospective observational study', BMJ Open Respiratory Research, vol. 6, no. 1, e000438. https://doi.org/10.1136/bmjresp-2019-000438
VITDALIZE Collaboration Group & Parekh, D 2019, 'Effect of high-dose vitamin D3 on 28-day mortality in adult critically ill patients with severe vitamin D deficiency: a study protocol of a multicentre, placebo-controlled double-blind phase III RCT (the VITDALIZE study)', BMJ open, vol. 9, no. 11, pp. e031083. https://doi.org/10.1136/bmjopen-2019-031083
Sapey, E, Patel, JM, Greenwood, H, Walton, GM, Grudzinska, F, Parekh, D, Mahida, RY, Dancer, RC, Lugg, ST, Howells, PA, Hazeldine, J, Newby, P, Scott, A, Nightingale, P, Hill, AT & Thickett, DR 2019, 'Simvastatin improves neutrophil function and clinical outcomes in pneumonia: a pilot randomized controlled clinical trial', American Journal of Respiratory and Critical Care Medicine, vol. 200, no. 10, pp. 1282-1293. https://doi.org/10.1164/rccm.201812-2328OC
Scott, A, Lugg, S, Aldridge, K, Lewis, K, Bowden, A, Mahida, R, Grudzinska, F, Dosanjh, D, Parekh, D, Foronjy, R, Sapey, E, Naidu, B & Thickett, D 2018, 'Pro-inflammatory effects of e-cigarette vapour condensate on human alveolar macrophages', Thorax, vol. 73, no. 12, pp. 1161-1169. https://doi.org/10.1136/thoraxjnl-2018-211663
Patel, J, Sapey, E, Parekh, D, Scott, A, Dosanjh, D, Gao Smith, F & Thickett, D 2018, 'Sepsis induces a dysregulated neutrophil phenotype that is associated with increased mortality', Mediators of Inflammation, vol. 2018, 4065362. https://doi.org/10.1155/2018/4065362, https://doi.org/10.1155/2018/4065362
Letter
Jasper, AE, Sapey, E, Thickett, D & Scott, A 2020, 'Comment on “E-cigarette use increases susceptibility to bacterial infection by impairment of human neutrophil chemotaxis, phagocytosis, and NET formation”', American Journal of Physiology - Cell Physiology, vol. 318, no. 3, pp. C704-C705. https://doi.org/10.1152/ajpcell.00554.2019
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