Recent publications
Article
Wijesinghe, S, Badoume, A, Nanus, D, Sharma-Oates, A, Farah, H, Certo, M, Alnajjar, FAQ, Davis, E, Mauro, C, Lindsay, MA & Jones, S 2023, 'Obesity defined molecular endotypes in the synovium of patients with osteoarthritis provides a rationale for therapeutic targeting of fibroblast subsets', Clinical and Translational Medicine, vol. 13, no. 4, e1232. https://doi.org/10.1002/ctm2.1232
Farah, H, Wijesinghe, S, Nicholson, T, Alnajjar, FAQ, Certo, M, Alghamdi, AMA, Davis, E, Young, S, Mauro, C & Jones, S 2022, 'Differential metabotypes in synovial fibroblasts and synovial fluid in hip osteoarthritis patients support inflammatory responses', International Journal of Molecular Sciences, vol. 23, no. 6, 3266. https://doi.org/10.3390/ijms23063266
Wijesinghe, SN, Brown, TJ, Nanus, DE, Housmans, B, Green, JA, Hackl, M, Choi, KK, Arkill, KP, Welting, T, James, V, Jones, SW, Peffers, MJ & Anderson, JR 2022, 'The role of extracellular vesicle miRNAs and tRNAs in synovial fibroblast senescence', Frontiers in Molecular Biosciences, vol. 9, 971621. https://doi.org/10.3389/fmolb.2022.971621
UK GAPP Study Group 2021, 'Novel gene variants in patients with platelet-based bleeding using combined exome sequencing and RNAseq murine expression data', Journal of Thrombosis and Haemostasis, vol. 19, no. 1, pp. 262-268. https://doi.org/10.1111/jth.15119
Nanus, D, Badoume, A, Wijesinghe, S, Halsey, A, Hurley, P, Ahmed, Z, Botchu, R, Davis, E, Lindsay, MA & Jones, S 2021, 'Synovial tissue from sites of joint pain in knee osteoarthritis patients exhibits a differential phenotype with distinct fibroblast subsets', EBioMedicine, vol. 72, 103618. https://doi.org/10.1016/j.ebiom.2021.103618
Alnajjar, FAQ, Sharma-Oates, A, Wijesinghe, S, Farah, H, Nanus, D, Nicholson, T, Davis, E & Jones, S 2021, 'The expression and function of metastases associated lung adenocarcinoma transcript-1 long non-coding RNA in subchondral bone and osteoblasts from patients with osteoarthritis', Cells, vol. 10, no. 4, 786. https://doi.org/10.3390/cells10040786
Chapter (peer-reviewed)
Wijesinghe, SN, Lindsay, MA & Jones, SW 2022, Long non-coding RNAs in rheumatology. in Advances in Experimental Medicine and Biology. vol. 1363, Advances in Experimental Medicine and Biology, Springer, pp. 35-70. https://doi.org/10.1007/978-3-030-92034-0_4
Abstract
Wijesinghe, SN, Acharjee, A, Russ, D, Gkoutos, G & Jones, SW 2024, '677 - Cross-species transcriptomics and machine learning identifies conserved obesity associated genes in osteoarthritic joint tissues', Osteoarthritis and Cartilage, vol. 32, no. Supplement 1, pp. S466-S467. https://doi.org/10.1016/j.joca.2024.02.692
Wijesinghe, SN, Botchu, R, Sardeli, AV, Ditchfield, CN, Davies, ET & Jones, SW 2024, '743 - Specific sites of patient-reported joint pain coincide with presence of bone marrow lesions in knee osteoarthritis patients', Osteoarthritis and Cartilage, vol. 32, no. Supplement 1, pp. S509-S510. https://doi.org/10.1016/j.joca.2024.02.758
Nanus, D, Wijesinghe, S, Pearson, M, Hadjicharalambous, MR, Rosser, A, Davis, E, Lindsay, M & Jones, S 2020, 'Clinical Connections: regulation of the inflammatory synovial fibroblast phenotype by metastasis-associated lung adenocarcinoma transcript 1 long noncoding RNA in obese patients with osteoarthritis', Arthritis and Rheumatology, vol. 72, no. 4, pp. A16-A16. https://doi.org/10.1002/art.40957
Nanus, D, Badoume, A, Wijesinghe, S, Hurley, P, Davis, E, Lindsay, M & Jones, S 2020, 'Identification of synovial fibroblasts subsets associated with pain and progression of knee osteoarthritis by single cell sequencing', Osteoarthritis and Cartilage, vol. 28, no. S86-S527, 189, pp. S133. https://doi.org/10.1016/j.joca.2020.02.220
Wijesinghe, S, Badoume, A, Nanus, D, Davis, E, Lindsay, M & Jones, S 2020, 'Obese synovial fibroblasts exhibit single cell subsets with specific pathological inflammatory functions in osteoarthritis patients', Osteoarthritis and Cartilage, vol. 28, no. S20-S85, 98, pp. S84. https://doi.org/10.1016/j.joca.2020.02.128
Review article
Nicholson, TA, Sagmeister, M, Wijesinghe, SN, Farah, H, Hardy, RS & Jones, SW 2023, 'Oligonucleotide Therapeutics for Age-Related Musculoskeletal Disorders: Successes and Challenges', Pharmaceutics, vol. 15, no. 1, 237. https://doi.org/10.3390/pharmaceutics15010237
Wijesinghe, S, Lindsay, MA & Jones, S 2021, 'Oligonucleotide therapies in the treatment of arthritis: a narrative review', Biomedicines, vol. 9, no. 8, 902. https://doi.org/10.3390/biomedicines9080902
Wijesinghe, S, Nicholson, T, Tsintzas, K & Jones, S 2020, 'Involvements of long noncoding RNAs in obesity‐associated inflammatory diseases', Obesity Reviews. https://doi.org/10.1111/obr.13156
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