Dr. Toescu graduated the Medical degree in Bucharest, Romania, where he practised general medicine for 1 year and a half, while maintaining an active interest in basic research. After leaving Romania, he arrived at the University of Oxford, where he worked as Departmental Demonstrator in the Dept. of Human Anatomy, while completing a D.Phil. project under the guidance of Drs. J.F. Morris and C.A.R. Boyd. The topic of research was an assessment of the of hormone secretion from the posterior pituitary gland, and the development of a model of secretory nerve terminals from this gland, called neurosecretosomes. After finishing the D.Phil, Dr. Toescu moved to Liverpool, to work with Prof. O.H. Petersen, in the Dept. Physiology, Liverpool University. The topic of research was the study of the mechanisms regulating the generation and propagation of the intracellular Ca2+ waves and Ca2+ oscillations, with a particular focus on the role of InsP3 and the ER Ca2+ stores in controlling such activities. After being offered an academic position in the Department of Physiology, Dr. Toescu moved to the University of Birmingham, where he returned to his interest in neurosciences and developed his current research portfolio, based on the study of the mechanisms of neuronal ageing.
As part of the academic activity, Dr. Toescu organised and continues to take part in a variety of international scientific meetings and symposia, from meetings organised under the auspices of national learned societies, such as Physiological Society or the British Neuroscience Association, or international organisms, such as the Federation of European Neuroscience Societies.
Dr. Toescu continues to maintain an interest in the development of the scientific establishment in his country of origin, Romania, where he collaborates with a number of research groups from several cities. Research collaboration are also taking place with research groups in Germany, France and Spain
Another important part of Dr. Toescu professional activity is dedicated to the process of public engagement with science, starting from the view that it is important for all scientists to present and engage the public in discussion on science and its methodologies. To this purpose he was the organiser, for a period of 3 years of the Birmingham’s Cafe Scientifique, while contributing also to the activities of the national network of Cafes. More recently he organised a city-wide series of events relating to the Brain Awareness Week initiative, including a Festival of Neurosciences.