Dr Sadaf Ali MBBS, MRCP

Dr Sadaf Ali

Department of Metabolism and Systems Science
Academic Clinical Lecturer Diabetes & Endocrinology

Contact details

Email
s.ali.15@bham.ac.uk
Twitter
@Sadafghaf87
View my research portal
Address
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Sadaf Ali is an NIHR academic clinical lecturer in diabetes and endocrinology at Metabolism and Systems Science, University of Birmingham. Her research is centred on unravelling the mechanisms underlying insulin resistance in obesity and type 2 diabetes, with a focus on utilizing Alström syndrome, a rare monogenic disorder, as a model for cardio-metabolic disease. Her research delves into investigating the dysfunction of adipose tissue and skeletal muscle as key contributors to insulin resistance.

Sadaf received her primary medical qualification in 2011 from Khyber Medical University, Peshawar, Pakistan before moving to UK. She completed her Core Medical Training and initial years of Higher Specialist Training in Diabetes & Endocrinology in the Northwest Region before relocating to Birmingham in 2021 to embark on her PhD journey.

In recognition of her academic prowess and dedication to medical research, Sadaf is currently appointed as an NIHR Academic Clinical Lecturer in Diabetes and Endocrinology. This prestigious appointment underscores her commitment to advancing knowledge in the field of diabetes and endocrinology while bridging the gap between academia and clinical practice.

Qualifications

  • Membership of the Royal College of Physicians, 2016
  • M.B.B.S., Khyber Medical University, Pakistan, 2011

Other activities

  • Committee member for SfE National Obesity Database Steering group
  • Member of Society of Endocrinology (SfE)
  • Member of Endocrine Society
  • Member of Diabetes UK(DUK)
  • Specialist Registrar in Diabetes Endocrinology, University Hospitals Birmingham NHS Foundation Trust

Publications

Recent publications

Article

Ali, S, Zhang, Q, Anwunah, I, Baig, S, da Silva Xavier, G, Dawson, C, Dassie, F, Tang, Y, Wang, L, Chang, G, Gleeson, P, Warfield, AT, Paisey, R, Barrett, TG, Maffei, P, Wang, X, Homer, V, Kershaw, M & Geberhiwot, T 2026, 'Defining Puberty and Spectrum of Hypogonadism in Alström Syndrome', Journal of Clinical Endocrinology and Metabolism, vol. 111, no. 1, pp. 33-44. https://doi.org/10.1210/clinem/dgaf356

Niven, J, Kucuk, S, Gope, A, Certo, M, Cassidy, FC, Arana Echarri, A, Ali, S, Ladoukakis, E, Vidali, S, Macchi, C, Amir, SS, Bergin, R, Davies, S, Perkin, OJ, Smith, J, Cucchi, D, Heneghan, H, Wijesinghe, S, Jenkins, BJ, Baig, S, Mahony, C, Chidomere, C, Sarkar, S, Nicolaou, A, Caamaño, J, Croft, A, Davies, E, Thompson, D, O’Shea, D, Jones, SW, Duggal, NA, Ruscica, M, Makarova, M, Jones, N, Da Silva Xavier, G, Geberhiwot, T, Turner, JE, Hogan, AE, Nedjai, B & Mauro, C 2026, 'DNA methylation-mediated memory of obesity in CD4 T lymphocytes perpetuates immune dysregulation', EMBO Reports. https://doi.org/10.1038/s44319-026-00765-w

Ali, S, Baig, S, Wanninayake, S, da Silva Xavier, G, Dawson, C, Paisey, R, Geberhiwot, T & Ali, S 2023, 'Glucagon-like peptide-1 analogues in monogenic syndromic obesity: Real-world data from a large cohort of Alström syndrome patients', Diabetes, obesity & metabolism, pp. 1-8. https://doi.org/10.1111/dom.15398

Abstract

Ali, S, Heising, S, Veeranna, V, Vincent, A, Xavier, GS, Geberhiwot, T & Ali, S 2024, '7086 Disrupted Mitochondrial Function in Alström Syndrome- A Monogenic Model of Insulin Resistance and Obesity', Journal of the Endocrine Society, vol. 8, no. Supplement_1, bvae163.738, pp. A387-A388. https://doi.org/10.1210/jendso/bvae163.738

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