Annie de Bray MBChB, PGCert Med Ed, MRCP(UK), DPhil

Annie de Bray

Department of Metabolism and Systems Science
Academic Clinical Lecturer in Diabetes and Endocrinology
Specialist Registrar in Diabetes and Endocrinology

Contact details

Address
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Annie is a Specialist Registrar in Diabetes and Endocrinology training in the West Midlands and holds a Academic Clinical Lecturer post working in the Department of Metabolism and Systems Science. Her main area of academic interest in the lab is incretin biology and clinically she is focused on transitional care of people living with obesity and type 2 diabetes.

She is currently undertaking a locally-funded Academic Clinical Lecturer post alongside completing clinical training at Birmingham Heartlands Hospital. Her projects include lab-based work exploring insulin resistance and GLP1R agonism and clinical and qualitative projects currently focused on young people with Wolfram Syndrome.

She has recently finished her tenure with a national training committee (the Young Diabetologists’ and Endocrinologists’ Forum) and has joined the Society for Endocrinology’s Metabolism and Obesity network working group

Qualifications

  • DPhil, University of Oxford, 2025
  • Specialty Certificate Examination (SCE) in Endocrinology and Diabetes, 2020
  • MRCP (UK), 2016
  • PGCert in Medical Education, University of Birmingham, 2015
  • MBChB, University of Birmingham, 2012

Biography

Annie graduated from the University of Birmingham in 2012 and completed her pre-specialty postgraduate training around the West Midlands, mainly in the Black Country. She obtained an NIHR-funded Academic Clinical Fellowship and started this post alongside specialty training in Diabetes and Endocrinology between 2017-2019.

Between 2022-2025, she completed an MRC-funded Clinical Research Training Fellowship to earn a DPhil with Professor David J Hodson and his lab in the Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM). Her DPhil centred on developing and validating novel fluorescent probes for the Glucose-dependent insulinotropic polypeptide receptor (GIPR) and the Glucagon-like peptide 1 receptor (GLP1R).

Teaching

Annie regularly takes opportunities to teach undergraduate and postgraduate colleagues and will be lecturing in an endocrinology Special Study Module.

Research

Annie is currently working with Dr Renuka Dias to assess if gonadal function is affected in young women with Wolfram Syndrome. They are also working with Professor Felicity Boardman (Warwick) to explore the future aspirations of young people with Wolfram Syndrome.

Annie is also working with Dr Gabriella Da Silver Xavier to investigate how GLP1R agonists might improve insulin resistance.

Publications

Recent publications

Article

de Bray, A, Roberts, AG, Armour, S, Tong, J, Huhn, C, Gatin-Fraudet, B, Roßmann, K, Shilleh, AH, Jiang, W, Figueredo Burgos, NS, Trott, JPP, Viloria, K, Nasteska, D, Pearce, A, Miyazaki, S, Tomlinson, JW, Owen, DM, Nieves, DJ, Ast, J, Cyranka, M, Epanchintsev, A, Ämmälä, C, Reimann, F, Soykan, T, Ladds, G, Adriaenssens, AE, Trapp, S, Jones, B, Broichhagen, J & Hodson, DJ 2025, 'Fluorescent GLP1R/GIPR dual agonist probes reveal cell targets in the pancreas and brain', Nature metabolism, vol. 7, no. 8, pp. 1536-1549. https://doi.org/10.1038/s42255-025-01342-6

de Bray, A, Schnitzer, H, Mahase, E, Singh, P, Andrews, R, McGowan, BM, Le Brocq, S, Wilding, JPH, Flint, SW & Hazlehurst, JM 2025, 'Variation in the Commissioning of Semaglutide for the Treatment of Obesity and Overweight Across England: Results of Three Freedom of Information‐Based Mapping Exercises Across the 42 Integrated Care Boards of England', Clinical Obesity. https://doi.org/10.1111/cob.70044

Wong, C, De Bray, A, Ul Hassan, N, Almohandes, A, Thant, KZ, Gill, S, Gill, D, Forsdick, H, Sinclair, AJ, Karamat, MA & Bellary, S 2024, 'Glycaemic outcomes in people living with diabetes under 65 and over 65 years old using an intermittently scanned continuous glucose monitoring system', Therapeutic Advances in Endocrinology and Metabolism, vol. 15. https://doi.org/10.1177/20420188241269133

Knowles, G, Warmington, E, Shepherd, LM, Hazlehurst, JM, de Bray, A, Gleeson, H, Arlt, W & Prete, A 2023, 'Impact of coronavirus disease 2019 on patients with primary adrenal insufficiency: a cross-sectional study', Endocrine Connections, vol. 12, no. 8, e230122. https://doi.org/10.1530/EC-23-0122

Kempegowda, P, Sunsoa, H, Chandan, J, Quinn, L, Amrelia, P, Atta, S, Amir, S, Teh, Y, Chaudhry, S, De Bray, A, Rashid, R, Whitehouse, J, Nash, E & Syed, A 2021, 'Retinopathy and microalbuminuria are common microvascular complications in cystic fibrosis-related diabetes', Therapeutic Advances in Endocrinology and Metabolism, vol. 11, pp. 1-10. https://doi.org/10.1177/2042018820966428

Kemkem, Y, Nasteska, D, De Bray, A, Bargi-Souza, P, Peliciari-Garcia, R, Guillou, A, Mollard, P, Hodson, D & Schaeffer, M 2020, 'Maternal hypothyroidism in mice influences glucose metabolism in adult offspring', Diabetologia, vol. 63, no. 9, pp. 1822-1835. https://doi.org/10.1007/s00125-020-05172-x

de Bray, AY, Sunsoa, H, McKemey, E, Kempegowda, P, Nash, EF & Syed, A 2019, 'Outcomes for patients using mono-or dual DPP4-inhibitor therapy for Cystic Fibrosis-Related Diabetes - a regional centre's 2-year experience', Journal of Cystic Fibrosis, vol. 18, pp. S142. https://doi.org/10.1016/s1569-1993(19)30593-4

Jawahar, N, Kempegowda, P, Chandan, J, Coombs, B, Bray, AD, James, S, Ghosh, S & Narendran, P 2019, 'Regular feedback on specific parameters may be required to maintain improvement in diabetic ketoacidosis management: results from a five-year quality improvement project - Virtual Meeting | EASD', Diabetologia, vol. 62, pp. S422-S422. <https://www.easd.org/virtualmeeting/home.html!resources/regular-feedback-on-specific-parameters-may-be-required-to-maintain-improvement-in-diabetic-ketoacidosis-management-results-from-a-five-year-quality-improvement-project>

Kempegowda, P, Bray, AD, Jawahar, N, Coombs, B, Ghosh, S & Narendran, P 2019, 'Regular monitoring of key performance parameters improves diabetic ketoacidosis (DKA) management but ongoing feedback is necessary to sustain improvement', Diabetic Medicine, vol. 36, pp. 164.

Kempegowda, P, Chandan, JS, Coombs, B, De Bray, A, Jawahar, N, James, S, Ghosh, S & Narendran, P 2019, 'Regular performance feedback may be key to maintain good quality DKA management: results from a five-year study', BMJ Open Diabetes Research and Care, vol. 7, no. 1, e000695. https://doi.org/10.1136/bmjdrc-2019-000695

De Bray, A, Hassan-Smith, Z, Dirie, J, Littleton, E, Chavda, S, Ayuk, J, Sanghera, P & Karavitaki, N 2018, 'Macroprolactinoma causing VI, X, XII cranial nerve palsies nearly 30 years after initial treatment', Endocrinology, Diabetes and Metabolism Case Reports , vol. 2018, no. 1. https://doi.org/10.1530/EDM-18-0053

Abstract

Kempegowda, P, Sunsoa, H, Amrelia, P, Chandan, JS, Teh, YS, Atta, SN, Amir, S, Chaudhry, S, De Bray, A, Rashid, R, Whitehouse, JL, Nash, EF & Syed, A 2019, 'P295 Regular specialist follow-up is essential for early detection and management of diabetes-related complications in patients with cystic fibrosis-related diabetes', Journal of Cystic Fibrosis, vol. 18, no. Supplement 1, pp. S140-S141. https://doi.org/10.1016/s1569-1993(19)30588-0

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