Recent publications
Article
Grech, O, Mugo, W, Hill, LJ, Heaselgrave, S, Alimajstorovic, Z, Yiangou, A, Lyons, HS, Mitchell, J, Lavery, GG, Fulton, D & Sinclair, AJ 2026, 'The metabolic consequences of evoked spreading depolarization in brain slices', Scientific Reports.
Mitchell, JL, Lyons, HS, Walker, JK, Yiangou, A, Thaller, M, Grech, O, Alimajstorovic, Z, Tsermoulas, G, Brock, K, Mollan, SP & Sinclair, AJ 2025, 'A randomized sequential cross-over trial evaluating five purportedly ICP-lowering drugs in idiopathic intracranial hypertension', Headache, vol. 65, no. 2, pp. 258-268. https://doi.org/10.1111/head.14897
Grech, O, Rubio-Beltran, E, Stanyer, EC, Labastida-Ramirez, A, Lavery, GG, Hill, LJ, Holland, PR & Sinclair, AJ 2025, 'Raised intracranial pressure alters cortical vascular function and cephalic allodynia', Brain. https://doi.org/10.1093/brain/awae415
Mugo, CW, Church, E, Horniblow, RD, Mollan, SP, Botfield, H, Hill, LJ, Sinclair, AJ & Grech, O 2025, 'Unravelling the gut-brain connection: a systematic review of migraine and the gut microbiome', The Journal of Headache and Pain, vol. 26, no. 1, pp. 125. https://doi.org/10.1186/s10194-025-02039-7
Grech, O, Mitchell, JL, Lyons, HS, Yiangou, A, Thaller, M, Tsermoulas, G, Brock, K, Mollan, SP & Sinclair, AJ 2024, 'Effect of glucagon like peptide-1 receptor agonist exenatide, used as an intracranial pressure lowering agent, on cognition in Idiopathic Intracranial Hypertension', Eye, vol. 38, no. 7, pp. 1374-1379. https://doi.org/10.1038/s41433-023-02908-y
Reyat, J, Sommerfeld, L, O'Reilly, M, Roth Cardoso, V, Thiemann, E, Khan, A, O'Shea, C, Harder, S, Müller, C, Barlow, J, Stapley, R, Chua, WWL, Kabir, N, Grech, O, Hummel, O, Hübner, N, Kaab, S, Mont, L, Hatem, SN, Winters, J, Zeemering, S, Morgan, N, Rayes, J, Gehmlich, K, Stoll, M, Brand, T, Schweizer , M, Piasecki, A, Schotten, U, Gkoutos, G, Lorenz, K, Cuello, F, Kirchhof, P & Fabritz, L 2024, 'PITX2 deficiency leads to atrial mitochondrial dysfunction', Cardiovascular Research. https://doi.org/10.1093/cvr/cvae169
Mollan, SP, Momin, SNA, Khatkar, PS, Grech, O, Sinclair, A & Tsermoulas, G 2023, 'A neuro-ophthalmologist’s guide to advances in intracranial pressure measurements', Eye and Brain, vol. 15, pp. 113-124. https://doi.org/10.2147/EB.S404642
Alimajstorovic, Z, Mitchell, J, Yiangou, A, Hancox, T, Southam, A, Grech, O, Ottridge, R, Winder, C, Tahrani, A, Tan, TM, Mollan, S, Dunn, W & Sinclair, A 2023, 'Determining the role of novel metabolic pathways in driving intracranial pressure reduction after weight loss', Brain Communications, vol. 5, no. 5, fcad272. https://doi.org/10.1093/braincomms/fcad272
Mitchell, JL, Lyons, HS, Walker, JK, Yiangou, A, Grech, O, Alimajstorovic, Z, Greig, NH, Li, Y, Tsermoulas, G, Brock, K, Mollan, SP & Sinclair, AJ 2023, 'The effect of GLP-1RA exenatide on idiopathic intracranial hypertension: a randomized clinical trial', Brain, vol. 146, no. 5, pp. 1821-1830. https://doi.org/10.1093/brain/awad003
Abstract
Hill, L, Begum, G, Hubbard, J, Mugo, C, Botfield, H, Lyons, H, Thaller, M, Yiangou, A, Grech, O, Mitchell, J, Mollan, S & Sinclair, A 2025, 'Identifying candidate molecular biomarkers in idiopathic intracranial hypertension patients (P7-2.008)', Neurology, vol. 104, no. 7 Supplement 1, 4448. https://doi.org/10.1212/WNL.0000000000211678
Review article
Lyons, HS, Hubbard, JC, Thomas, CN, Roberts, JA, Mugo, CW, Bellamy Plaice, G, Grech, O, Prosser, S, Strom, A, Lucas, SJE, Downie, LE, Gill, JM, Mitchell, JL, Sinclair, AJ, Hill, LJ & UK mTBI Predict Consortium 2026, 'Biofluid-based predictors of post-concussion symptoms: a narrative review of mild traumatic brain injury biomarkers', Brain Communications, vol. 8, no. 1, fcaf501. https://doi.org/10.1093/braincomms/fcaf501
Anwar, F, Grech, O, Mugo, CW, Roberts, JA, Hubbard, JC, Thomas, CN, Sinclair, AJ & Hill, LJ 2025, 'A systematic review of the causes and consequences of spreading depolarization in neuroinflammation; implications for neurovascular disorders', Journal of Neuroinflammation, vol. 22, no. 1, 178. https://doi.org/10.1186/s12974-025-03503-6
UK mTBI Predict Consortium, Sassani, M, Ghafari, T, Arachchige, PRW, Idrees, I, Gao, Y, Waitt, A, Weaver, SRC, Mazaheri, A, Lyons, HS, Grech, O, Thaller, M, Witton, C, Bagshaw, AP, Wilson, M, Park, H, Brookes, M, Novak, J, Mollan, SP, Hill, LJ, Lucas, SJE, Mitchell, JL, Sinclair, AJ, Mullinger, K & Fernandez-Espejo, D 2025, 'Current and prospective roles of magnetic resonance imaging in mild traumatic brain injury', Brain Communications. https://doi.org/10.1093/braincomms/fcaf120
Lyons, H, Sassani, M, Hyder, Y, Mitchell, J, Thaller, M, Mollan, S, Sinclair, A, Blanch, R & mTBI Predict Consortium 2024, 'A systematic review of optical coherence tomography findings in adults with mild traumatic brain injury', Eye, vol. 38, no. 6, pp. 1077-1083. https://doi.org/10.1038/s41433-023-02845-w
UK mTBI Predict Consortium, Lyons, HS, Sassani, M, Thaller, M, Yiangou, A, Grech, O, Mollan, SP, Wilson, DR, Lucas, SJE, Mitchell, JL, Hill, LJ & Sinclair, AJ 2024, 'Evaluating the Phenotypic Patterns of Post-Traumatic Headache: A Systematic Review of Military Personnel', Military medicine. https://doi.org/10.1093/milmed/usae353
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