Dr Hannah R Nieto BSc MBBS MRCS PhD

Hannah Nieto

Institute of Metabolism and Systems Research
Academic Clinical Lecturer

Contact details

Address
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Hannah is an NIHR Academic Clinical Lecturer in Otorhinolaryngology (ENT surgery) working in the IMSR, supervised by Professor Chris McCabe and Mr Neil Sharma. Her interests are thyroid cancer, molecular genomics, bioinformatics and sequencing.

Qualifications

  • PhD in Molecular Biology, Univeristy of Birmingham, 2020
  • MRCS, Royal College of Surgeons England, 2011
  • MBBS, Imperial College London, 2009
  • BSc (Hons) in Medical Sciences with Surgery and Anaesthesia, Imperial College London, 2007

Biography

Hannah is an NIHR Academic Clinical Lecturer in Otorhinolaryngology (ENT surgery) working in the field of thyroid molecular genomics, with an interest in thyroid cancer and bioinformatics. She enjoys teaching, training junior doctors in theatre, clinics and other clinical settings, teaching regularly at the UoB early years small group teaching sessions and at the West Midlands Emergency ENT course. She is supervised in her current role by by Prof Chris McCabe and Mr Neil Sharma.

Teaching

  • Thyroid and HPA small group teaching sessions, University of Birmingham 2015 – current
  • ENT West Midlands emergency course 2019 – current
  • ITM fellowship teaching - weekly teaching medical students (year 3) on clincal examinations, 2015-2016
  • Anatomy demonstrator under Professor Peter Abrahams 2010 – 2011

Other activities

  • British Thyroid Association Executive committee, 2019 - current
  • Student & Foundation Doctors in Otolaryngology (SFO) committee academic representative,  2020 - present
  • ENT Head and Neck SpR at the Queen Elizabeth Hospital, Oct 2020 - current
  • ENT Higher Surgical Training Representative - Representing HST trainees at Health Education England West Midlands Regional HST meetings (and one HEE WM Postgraduate School of Surgery meeting), Oct 2018 – Oct 2020

Publications

Recent publications

Article

Fletcher, A, Read, M, Thornton, C, Larner, D, Poole, V, Brookes, K, Nieto, H, Alshahrani, M, Thompson, R, Lavery, G, Landa, I, Fagin, JA, Campbell, MJ, Boelaert, K, Turnell, A, Smith, V & McCabe, C 2020, 'Targeting novel sodium iodide symporter interactors ADP-ribosylation factor 4 and valosin-containing protein enhances radioiodine uptake', Cancer Research, vol. 80, no. 1, pp. 102–115. https://doi.org/10.1158/0008-5472.CAN-19-1957

Alshahrani, M, Fletcher, A, Thornton, C, Brookes, K, Nieto, H, Thompson, R, Read, M, Boelaert, K, McCabe, C & Smith, V 2018, 'Biochemical analysis of radioiodine uptake enhancement in endocrine cancer', Endocrine Abstracts, vol. 59, OC2.4. https://doi.org/10.1530/endoabs.59.OC2.4

Read, M, Modasia, B, Fletcher, A, Thompson, R, Brookes, K, Rae, P, Nieto, H, Poole, V, Roberts, S, Campbell, M, Boelaert, K, Turnell, A, Smith, V, Mehanna, H & McCabe, C 2018, 'PTTG and PBF functionally interact with p53 and predict overall survival in head and neck cancer', Cancer Research, vol. 78, no. 20, pp. 5863-5876. https://doi.org/10.1158/0008-5472.CAN-18-0855

Read, M, Fong, J, Modasia, B, Fletcher, A, Imruetaicharoenchoke, W, Thompson, R, Nieto, H, Reynolds, J, Bacon, A, Mallick, U, Hackshaw, A, Watkinson, J, Boelaert, K, Turnell, A, Smith, V & McCabe, C 2017, 'Elevated PTTG and PBF predicts poor patient outcome and modulates DNA damage response genes in thyroid cancer', Oncogene, vol. 36, pp. 5296–5308. https://doi.org/10.1038/onc.2017.154

Imruetaicharoenchoke, W, Fletcher, A, Lu, W, Watkins, RJ, Modasia, B, Poole, V, Nieto, H, Thompson, R, Boelaert, K, Read, M, Smith, V & McCabe, C 2017, 'Functional consequences of the first reported mutations of the proto-oncogene PTTG1IP/PBF', Endocrine-related cancer, vol. 24, no. 9, pp. 459-474. https://doi.org/10.1530/ERC-16-0340

Nieto, H & Boelaert, K 2016, 'Thyroid stimulating hormone in thyroid cancer: does it matter?', Endocrine-related cancer, vol. 23, no. 11, ERC-16-0328. https://doi.org/10.1530/ERC-16-0328

Abstract

Read, M, Brookes, K, Fletcher, A, Thornton, C, Alshahrani, M, Khan, R, Nieto, H, Adcock, H, Webster, J, Cox, L, Alderwick, L, Boelaert, K, Smith, V & McCabe, C 2020, 'Drug repurposing identifies inhibitors of the proteostasis network to augment radioiodine uptake in combinatorial approaches targeting thyroid cancer', Journal of the Endocrine Society, vol. 4, no. Issue Supplement 1, OR28-03. https://doi.org/10.1210/jendso/bvaa046.2135

Read, M, Modasia, B, Fletcher, A, Thompson, R, Brookes, K, Nieto, H, Campbell, M, Boelaert, K, Turnell, A, Smith, V, Mehanna, H & McCabe, C 2018, 'Oncogenic action of pituitary-tumor transforming gene (PBF) in head and neck cancer is associated with poorer overall survival', Endocrine Abstracts, vol. 59, P119. https://doi.org/10.1530/endoabs.59.P119

Read, M, Fong, J, Imruetaicharoenchoke, W, Modasia, B, Nieto, H, Fletcher, A, Thompson, R, Sharma, N, Watkinson, J, Turnell, A, Boelaert, K, Smith, V & McCabe, C 2017, 'Comparative analysis of human and mouse expression data identifies proto-oncogene PTTG- and PBF-associated genes in thyroid cancer', Thyroid Research, vol. 10(Suppl 1), no. 2. https://doi.org/10.1186/s13044-016-0036-8

Read, M, Fong, J, Imruetaicharoenchoke, W, Modasia, B, Nieto, H, Watkinson, J, Boelaert, K, Smith, V, Turnell, A & McCabe, C 2016, 'Comparative analysis of human and mouse expression data identifies distinct proto-oncogene PBF- and PTTG-associated genes in thyroid cancer', European Journal of Cancer, vol. 61, no. Suppl 1, 202, pp. S36.

Read, M, Fong, J, Imruetaicharoenchoke, W, Modasia, B, Nieto, H, Fletcher, A, Thompson, R, Sharma, N, Watkinson, J, Turnell, A, Boelaert, K, Smith, V & McCabe, C 2016, 'Comparative analysis of human and mouse expression data identifies proto-oncogene PTTG- and PBF-associated genes in thyroid cancer', Therapeutic Horizons in Endocrinology & Diabetes & 64th Annual meeting of the British Thyroid Association, Newcastle, United Kingdom, 12/05/16 - 13/05/16.

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