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Zannat, R, Lee, J, Muzaffar, J, Read, M, Brookes, K, Sharma, N, Boelaert, K, McCabe, C & Nieto, H 2023, 'The potential interaction between medical treatment and radioiodine treatment success: A systematic review.', Frontiers in Endocrinology, vol. 13, 1061555. https://doi.org/10.3389/fendo.2022.1061555
Fletcher, A, Read, M, Thornton, C, Larner, D, Poole, V, Brookes, K, Nieto, H, Alshahrani, M, Thompson, R, Lavery, G, Landa, I, Fagin, JA, Campbell, MJ, Boelaert, K, Turnell, A, Smith, V & McCabe, C 2020, 'Targeting novel sodium iodide symporter interactors ADP-ribosylation factor 4 and valosin-containing protein enhances radioiodine uptake', Cancer Research, vol. 80, no. 1, pp. 102–115. https://doi.org/10.1158/0008-5472.CAN-19-1957
Alshahrani, M, Fletcher, A, Thornton, C, Brookes, K, Nieto, H, Thompson, R, Read, M, Boelaert, K, McCabe, C & Smith, V 2018, 'Biochemical analysis of radioiodine uptake enhancement in endocrine cancer', Endocrine Abstracts, vol. 59, OC2.4. https://doi.org/10.1530/endoabs.59.OC2.4
Read, M, Modasia, B, Fletcher, A, Thompson, R, Brookes, K, Rae, P, Nieto, H, Poole, V, Roberts, S, Campbell, M, Boelaert, K, Turnell, A, Smith, V, Mehanna, H & McCabe, C 2018, 'PTTG and PBF functionally interact with p53 and predict overall survival in head and neck cancer', Cancer Research, vol. 78, no. 20, pp. 5863-5876. https://doi.org/10.1158/0008-5472.CAN-18-0855
Abstract
Brookes, K, Zha, L, Kim, J, Small, B, Kocbiyik, M, Manivannan, S, Kannappan, V, Wang, W, Sunassee, K, Blower, P, Nieto, H, Smith, V, Read, M & McCabe, C 2023, 'Copper-based therapeutics increase sodium/iodide symporter (NIS) transcription and enhance radioiodide uptake in thyroid cancer cells', Endocrine Abstracts, vol. 90, OC11.1. https://doi.org/10.1530/endoabs.90.OC11.1
Read, M, Brookes, K, Zha, L, Thornton, C, Kim, J, Fletcher, A, Firth, G, Sunassee, K, Blower, P, Nieto, H, Smith, V & McCabe, C 2022, 'Dissecting endocytic mechanisms reveals new molecular targets to enhance sodium iodide symporter activity with clinical relevance to radioiodide therapy', Thyroid, vol. 32, no. S1, OC29, pp. A92-A92. https://doi.org/10.1089/thy.2022.29137.abstracts
Zha, L, Brookes, K, Thornton, C, Fletcher, A, Kim, J, Sunassee, K, Blower, P, Nieto, H, Smith, V, Read, M & McCabe, C 2022, 'Enhancing radioiodide uptake by addressing the mechanism of sodium/iodide symporter (NIS) endocytosis', Endocrine Abstracts, vol. 86, OC6.2. https://doi.org/10.1530/endoabs.86.OC6.2
Manivannan, S, Alshahrani, M, Thornton, C, Raja, S, Kocbiyik, M, Zha, L, Brookes, K, Nieto, H, Read, M, McCabe, C & Smith, V 2022, 'Promotion of thyroid cancer cell migration and invasion by the proto-oncogene PBF is mediated by FGD1 and N-WASP', Thyroid, vol. 32, no. S1, OC27, pp. A91-A91. https://doi.org/10.1089/thy.2022.29137.abstracts
Read, M, Brookes, K, Zha, L, Moolla, M, Kocbiyik, M, Manivannan, S, Hoare, R, Kannappan, V, Wang, W, Sunassee, K, Blower, P, Nieto, H, Smith, V & McCabe, C 2022, 'Repurposing disulfiram as a therapeutic agent to enhance sodium iodide symporter activity in radioiodide therapy', Endocrine Abstracts, vol. 86, OC2.6. https://doi.org/10.1530/endoabs.86.OC2.6
Brookes, K, Zha, L, Moolla, M, Kim, J, Kocbiyik, M, Manivannan, S, Nieto, H, Kannappan, V, Wang, W, Sunassee, K, Blower, P, Smith, V, Read, M & McCabe, C 2022, 'Repurposing of disulfiram and diethyldithiocarbamate (DDC)-metal complexes to enhance sodium iodide symporter function in radioiodide therapy', Thyroid, vol. 32, no. S1, OC40, pp. A96-A97. https://doi.org/10.1089/thy.2022.29137.abstracts
Thornton, C, Brookes, K, Fletcher, A, Nieto, H, Zha, L, Kocbiyik, M, Read, M, Smith, V & McCabe, C 2021, 'AP-2 and moesin regulate the internalisation of the sodium-iodide symporter and affect I125 Uptake in thyroid cancer cells', Endocrine Abstracts, vol. 77, OC6.4. https://doi.org/10.1530/endoabs.77.OC6.4
Read, M, Brookes, K, Thornton, C, Nieto, H, Zha, L, Fletcher, A, Boelaert, K, Smith, V & McCabe, C 2021, 'An emerging role for proteostasis modulators targeting NIS activity to enhance radioiodide therapy in thyroid cancer', Endocrine Abstracts, vol. 77, OC2.2. https://doi.org/10.1530/endoabs.77.OC2.2
Read, M, Brookes, K, Fletcher, A, Thornton, C, Alshahrani, M, Khan, R, Nieto, H, Adcock, H, Webster, J, Cox, L, Alderwick, L, Boelaert, K, Smith, V & McCabe, C 2020, 'Drug repurposing identifies inhibitors of the proteostasis network to augment radioiodine uptake in combinatorial approaches targeting thyroid cancer', Journal of the Endocrine Society, vol. 4, no. Issue Supplement 1, OR28-03. https://doi.org/10.1210/jendso/bvaa046.2135
Read, M, Modasia, B, Fletcher, A, Thompson, R, Brookes, K, Nieto, H, Campbell, M, Boelaert, K, Turnell, A, Smith, V, Mehanna, H & McCabe, C 2018, 'Oncogenic action of pituitary-tumor transforming gene (PBF) in head and neck cancer is associated with poorer overall survival', Endocrine Abstracts, vol. 59, P119. https://doi.org/10.1530/endoabs.59.P119
Preprint
Read, M, Brookes, K, Zha, L, Manivannan, S, Kim, J, Kocbiyik, M, Fletcher, A, Gorvin, CM, Firth, G, Fruhwirth, G, Nicola, J, Jhiang, S, Ringel, M, Campbell, M, Sunassee, K, Blower, P, Boelaert, K, Nieto, H, Smith, V & McCabe, C 2023 'Dissecting endocytic mechanisms reveals new molecular targets to enhance sodium iodide symporter activity with clinical relevance to radioiodide therapy' bioRxiv. https://doi.org/10.1101/2023.05.22.541733
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