Dr Hannah R Nieto BSc MBBS FRCS (ORL-HNS) PhD

Hannah Nieto

Department of Metabolism and Systems Science
Clinician Scientist

Contact details

Address
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Qualifications

  • FRCS, Royal College of Surgeons England, 2021
  • PhD in Molecular Biology, Univeristy of Birmingham, 2020
  • MBBS, Imperial College London, 2009
  • BSc (Hons) in Medical Sciences with Surgery and Anaesthesia, Imperial College London, 2007

Biography

Hannah Nieto has recently been appointed as a Clinician Scientist on a BHP Fellowship at the University of Birmingham. Hannah is a Head and Neck and Thyroid surgeon, trained in Otorhinolaryngology (ENT surgery) in the West Midlands, and is currently undertaking a clinical Advanced H&N fellowship at the Manchester Royal Infirmary. Academically Hannah is working in the field of thyroid molecular genomics, with an interest in thyroid cancer and bioinformatics. Hannah delivers modules on statistics and bioinformatics at UoB for intercalated students and supervises iMSc Anatomy students, coaching them through performing systematic reviews and metanalyses. Her PhD was completed in the molecular biology of thyroid cancer recurrence, encompassing programming and wet lab discovery science. Hannah sits on the national ENT NIHR CRN. Her research focus now is genetics in diagnostics and prognostics in thyroid cancer.

Teaching

  • Bioinformatics and Statistics for iMSc intercalating medical students 
  • Thyroid and HPA small group teaching sessions, University of Birmingham 2015 – current
  • ENT West Midlands FRCS course
  • ENT West Midlands emergency course
  • ITM fellowship teaching – clincal medical students on clinical examinations
  • Anatomy demonstrator under Professor Peter Abrahams 2010 – 2011

Postgraduate supervision

Hannah is currently supervising clinical/discovery science PhDs, please get in contact if you would like to discuss this further.

Other activities

  • ENT National NIHR CRN 2021 - current
  • British Thyroid Association Executive committee, 2019 - 2023
  • Student & Foundation Doctors in Otolaryngology (SFO) committee,  2020 - present
  • Post-CCT Training Interface Groups Fellowship national representative

Publications

Recent publications

Article

Manivannan, S, Kocbiyik, M, Banga, D, Nieto, H, Thomas, S, Read, M, McCabe, C & Smith, V 2024, 'Proto-oncogene regulation of thyroid cancer cell motility through altered focal adhesions', Thyroid, vol. 34, no. S1, Poster 0208, pp. A52-A52. https://doi.org/10.1089/thy.2024.89756.rc.abstracts

Abstract

Wongsanit, S, Read, M, Zha, L, Brookes, K, Fear, J, Khine, M, Nieto, H, Smith, V & McCabe, C 2025, 'Advancing CRISPR‑Driven Strategies for Enhancing Sodium Iodide Symporter Function via HiBiT Tagging', Thyroid Research, vol. 18 , no. Suppl 1, OR2. https://doi.org/10.1186/s13044-025-00258-3

Banga, D, Manivannan, S, Hariharan, A, Nieto, H, Brookes, K, Read, M, McCabe, C, Heath, V & Smith, V 2025, 'A potential new role for the proto-oncogene PBF in endocrine cancer as a regulator of endothelial cells and angiogenesis', Endocrine Abstracts, vol. 109, P94. https://doi.org/10.1530/endoabs.109.P94

Read, M, Brookes, K, Fear, J, Wongsanit, S, Small, B, Jones, A, Pham, T, Khine, M, Manivannan, S, Nieto, H, Stover, D, Jhiang, S, Kannappan, V, Wang, W, Sunassee, K, Blower, P, Ringel, M, Campbell, M, Boelaert, K, Smith, V & McCabe, C 2025, 'Combinatorial drug strategy targeting sodium iodide symporter (NIS) activity enhances radionuclide uptake in breast and thyroid settings in vivo', Endocrine Abstracts, vol. 109, OC2.6. https://doi.org/10.1530/endoabs.109.OC2.6

Wongsanit, S, Zha, L, Brookes, K, Fear, J, Khine, MT, Nieto, H, Smith, VE, Read, ML & McCabe, C 2025, 'CRISPR-Mediated HiBiT Tagging of the Sodium Iodide Symporter to Facilitate Novel High-Throughput Drug Screening Approaches', Thyroid, vol. 35, no. S1, Oral 023, pp. e8-e8. https://doi.org/10.1177/10507256251379060

Read, M, Brookes, K, Fear, JS, Wongsanit, S, Small, B, Jones, A, Manivannan, S, Khine, MT, Pharm, T, Nieto, H, Stover, D, Kannappan, V, Wang, W, Blower, P, Sunassee, K, Ringel, M, Campbell, M, Boelaert, K, Smith, VE & McCabe, CJ 2025, 'Dual targeting of sodium iodide symporter (NIS) maximises radionuclide uptake in breast and thyroid cancer with implications for stratifying patient recurrence risk', Thyroid Research, vol. 18, no. Suppl 1, OR5. https://doi.org/10.1186/s13044-025-00258-3

Read, ML, Brookes, K, Fear, JS, Wongsanit, S, Khine, MT, Small, B, Thornton, CEM, Moolla, M, Jones, A, Kim, J, Manivannan, S, Pharm, TT, Nieto, HR, Stover, DG, Kannappan, V, Wang, W, Blower, PJ, Sunassee, K, Ringel, MD, Campbell, MJ, Boelaert, K, Smith, VE & McCabe, CJ 2025, 'Dual Targeting using SAHA and Diethyldithiocarbamate (DDC)-Metal Complexes Augments Sodium Iodide Symporter Function in Thyroid and Breast Cancer', Thyroid, vol. 35, no. S1, Oral 028, pp. e10-e10. https://doi.org/10.1177/10507256251379060

Khine, MT, Brookes, K, Fear, JS, Wongsanit, S, Smith, VE, Read, ML, Nieto, HR, Boelaert, K & McCabe, CJ 2025, 'Functional impact of new repressors of radioiodide uptake', Thyroid Research, vol. 18, no. Suppl 1, PO6. https://doi.org/10.1186/s13044-025-00258-3

Khine, MT, Brookes, K, Fear, JS, Wongsanit, S, Read, ML, Nieto, HR, Boelaert, K, McCabe, CJ & Smith, VE 2025, 'Functional impact of new repressors of radioiodide uptake', Thyroid, vol. 35, no. S1, Poster 182, pp. e41-e42. https://doi.org/10.1177/10507256251379060

Manivannan, S, Kocbiyik, M, Banga, D, Nieto, H, Thomas, S, Read, ML, McCabe, CJ & Smith, VE 2025, 'PBF-Mediated Focal Adhesion Dynamics: A Key Driver of Thyroid Cancer Cell Motility', Thyroid, vol. 35, no. S1, Poster 174, pp. e39-e39. https://doi.org/10.1177/10507256251379060

Manivannan, S, Kocbiyik, M, Banga, D, Nieto, HR, Thomas, S, Read, ML, McCabe, CJ & Smith, VE 2025, 'PBF‑Mediated Focal Adhesion Dynamics: A Key Driver of Thyroid Cancer Cell Motility', Thyroid Research, vol. 18, no. Suppl 1, OR3. https://doi.org/10.1186/s13044-025-00258-3

Manivannan, S, Kocbiyik, M, Banga, D, Hariharan, A, Nieto, H, Thomas, S, Read, M, McCabe, C & Smith, V 2025, 'PBF-mediated focal adhesion dynamics: a key driver of thyroid cancer cell motility', Endocrine Abstracts, vol. 109, OP5.1. https://doi.org/10.1530/endoabs.109.OP5.1

Wongsanit, S, Read, M, Zha, L, Brookes, K, Fear, J, Khine, M, Nieto, H, Smith, V & McCabe, C 2025, 'Towards enhancing sodium iodide symporter function in thyroid cancer: HiBiT tagging and CRISPR-driven drug discovery', Endocrine Abstracts, vol. 109, OC4.2. https://doi.org/10.1530/endoabs.109.OC4.2

Manivannan, S, Kocbiyik, M, Banga, D, Afzal, A, Zha, L, Brookes, K, Nieto, HR, Thomas, S, Read, ML, McCabe, CJ & Smith, VE 2024, 'Proto-oncogene PBF regulation of cell adhesion and motility', Thyroid Research, vol. 17, no. S1, PO3. https://doi.org/10.1186/s13044-024-00203-w

Preprint

Brookes, K, Thornton, CEM, Zha, L, Kim, J, Small, B, Fear, JS, Nieto, HR, Western, H, Jones, A, Pham, TT, Bottegoni, G, Cox, LR, Kannappan, V, Wang, W, Gorvin, CM, Stover, DG, Spitzweg, C, Jhiang, S, Ringel, MD, Campbell, MJ, Sunassee, K, Blower, PJ, Boelaert, K, Smith, VE, Read, ML & McCabe, CJ 2024 'Clinical Implications of Dually Targeting the Sodium Iodide Symporter in Canonical and Non-Canonical Settings' SSRN. <https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4996070>

View all publications in research portal